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The map label for this gene is sspA [H]

Identifier: 57650242

GI number: 57650242

Start: 1063016

End: 1064026

Strand: Reverse

Name: sspA [H]

Synonym: SACOL1057

Alternate gene names: 57650242

Gene position: 1064026-1063016 (Counterclockwise)

Preceding gene: 57650243

Following gene: 57650241

Centisome position: 37.87

GC content: 36.99

Gene sequence:

>1011_bases
ATGAAAGGTAAATTTTTAAAAGTTAGTTCTTTATTCGTTGCAACTTTGACAACAGCGACACTTGTGAGTTCTCCAGCAGC
AAACGCGTTATCTTCAAAGGCTATGGACAATCATCCACAACAAACGCAGTCAAGCAAACAGCAAACACCTAAGATTCAAA
AAGGCGGTAACCTTAAACCATTAGAACAACGTGAACACGCAAATGTTATATTACCAAATAACGATCGTCACCAAATCACA
GATACAACGAATGGTCATTATGCACCCGTAACTTATATTCAAGTTGAAGCACCTACTGGTACATTTATTGCTTCCGGTGT
AGTTGTAGGTAAAGATACTCTTTTAACAAATAAACACGTCGTAGATGCTACGCACGGTGATCCTCATGCTTTAAAAGCAT
TCCCTTCTGCAATTAACCAAGACAATTATCCAAATGGTGGTTTCACTGCTGAACAAATCACTAAATATTCAGGCGAAGGT
GATTTAGCAATAGTTAAATTCTCCCCTAATGAGCAAAACAAACATATTGGTGAAGTAGTTAAACCAGCAACAATGAGTAA
TAATGCTGAAACACAAGTTAACCAAAATATTACTGTAACAGGATATCCTGGTGATAAACCTGTAGCAACAATGTGGGAAA
GTAAAGGAAAAATCACTTACCTCAAAGGCGAAGCTATGCAATATGATTTAAGTACAACTGGTGGTAATTCAGGTTCACCT
GTATTTAATGAAAAAAATGAAGTGATCGGAATTCATTGGGGCGGTGTACCAAATGAATTTAATGGTGCGGTATTTATTAA
TGAAAATGTACGCAACTTCTTAAAACAAAATATTGAAGATATCCATTTTGCCAACGATGACCAACCTAATAACCCAGATA
ATCCTGATAACCCTAACAATCCTGATAACCCTAACAACCCAGATGAACCAAATAACCCTGACAACCCTAACAACCCTGAT
AATCCAGACAATGGCGATACCAATAATTCAGACAATCCAGATGCAGCTTAA

Upstream 100 bases:

>100_bases
ATCTTTACAAAAACTTTTTAATTTATTTATATATTCTTATTGACTTAAAAATTTTTAGTGTTATATTTAACTTGTAAATA
AATTTTTTGGAGGTTTTTAG

Downstream 100 bases:

>100_bases
TTAACAATTAAGTTCGTCTAGATAAAATAGAAGCAAAGTCTTAGCAACGTAAAATATTTTGATTTAAATGGAGGGTATTA
TATGAATAGTTCATGTAAAT

Product: V8 protease

Products: NA

Alternate protein names: Endoproteinase Glu-C; Staphylococcal serine proteinase; V8 protease; V8 proteinase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQIT
DTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG
DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP
VFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPD
NPDNGDTNNSDNPDAA

Sequences:

>Translated_336_residues
MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQIT
DTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG
DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP
VFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPD
NPDNGDTNNSDNPDAA
>Mature_336_residues
MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQIT
DTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG
DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP
VFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPD
NPDNGDTNNSDNPDAA

Specific function: Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease s

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256
- InterPro:   IPR008353 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: =3.4.21.19 [H]

Molecular weight: Translated: 36313; Mature: 36313

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00672 V8_HIS ; PS00673 V8_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKP
CCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCC
LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV
CCHHCCCCEEECCCCCEEEECCCCCCCCEEEEEEEECCCCCEEECCEEECCCEEEECCEE
VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVV
EECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
KPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP
CCCCCCCCCCEEECCCEEEEECCCCCCHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCC
VFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNN
CCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCC
PDNPNNPDEPNNPDNPNNPDNPDNGDTNNSDNPDAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKP
CCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCC
LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV
CCHHCCCCEEECCCCCEEEECCCCCCCCEEEEEEEECCCCCEEECCEEECCCEEEECCEE
VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVV
EECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
KPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP
CCCCCCCCCCEEECCCEEEEECCCCCCHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCC
VFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNN
CCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCC
PDNPNNPDEPNNPDNPNNPDNPDNGDTNNSDNPDAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA