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The map label for this gene is comK [H]

Identifier: 57650217

GI number: 57650217

Start: 1042540

End: 1043070

Strand: Reverse

Name: comK [H]

Synonym: SACOL1032

Alternate gene names: 57650217

Gene position: 1043070-1042540 (Counterclockwise)

Preceding gene: 57650219

Following gene: 57650208

Centisome position: 37.13

GC content: 30.13

Gene sequence:

>531_bases
ATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAACGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCA
AAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCAAATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGA
CAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTACTAACACCATTATTTCCAACTTATTTTTTCCCAACACAT
TCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTATATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAA
AGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTTCATACCACAGTTTATGGCATCAATATAACAATTCCATTT
TTTACTATTACATGGTAGATAAACAATCTCGCATGATATCAAAAAATCCCGACCAACCAATAGATTATAATAAAGCCACA
TTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGAAGATAAATAA

Upstream 100 bases:

>100_bases
TATATCATTAATTGTATTTTTATATTAATGGTTTAAAACTTAATAAAGCGAGGTTTTGCTTATGTATTCTCAAAATATTT
ATGTGATACGCAAAGGAGAC

Downstream 100 bases:

>100_bases
ATTGTTTATTTTTAAAATATGCGGAATGTTTTATAAATATAGTGTAAATGTTCTGCATATTTTTTTAAGGTATCTATTGC
AAATTAACTTAATCTTGTTA

Product: ComK family protein

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLFPTYFFPTH
SDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKAT
LNVFEALTRYSLFEDK

Sequences:

>Translated_176_residues
MVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLFPTYFFPTH
SDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKAT
LNVFEALTRYSLFEDK
>Mature_176_residues
MVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLFPTYFFPTH
SDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKAT
LNVFEALTRYSLFEDK

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 21033; Mature: 21033

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGI
CEECCCCCCCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
SSKPPILLTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHV
CCCCCEEEEECCCCEECCCCCCCCCCCEEEEEHHHHHHHHHHCCEEEEEEECCCEEEEEE
SYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKATLNVFEALTRYSLFEDK
HHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGI
CEECCCCCCCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
SSKPPILLTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHV
CCCCCEEEEECCCCEECCCCCCCCCCCEEEEEHHHHHHHHHHCCEEEEEEECCCEEEEEE
SYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKATLNVFEALTRYSLFEDK
HHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]