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The map label for this gene is walR [H]

Identifier: 57238099

GI number: 57238099

Start: 1276289

End: 1276963

Strand: Reverse

Name: walR [H]

Synonym: CJE1362

Alternate gene names: 57238099

Gene position: 1276963-1276289 (Counterclockwise)

Preceding gene: 57238100

Following gene: 57238098

Centisome position: 71.83

GC content: 31.26

Gene sequence:

>675_bases
ATGACAAATATTCTTATGATAGAAGATGATTTAGAATTAGCAGAAATTACAGCTGAATATTTGGAAAAATTTGATATGAA
AGTTGATATAGCTCATGAACCTTATATAGGTCTTTCTAAGCTTGCATTAAAAGAATATCAGCTTATCATTTTAGACCTTT
CTTTGCCAGGGCTTGATGGGCTTGAAGTGTGTGAAGAGATTCGTAAAAAGTATGATACGCCTATTATTGTTTCAAGCGCA
AGACATGATATTACAGATAAGGTTAATGCTTTAGAGCTTGGAGCAGATGATTACCTACCAAAACCTTATAATCCAAAAGA
ATTACAAGCACGCATTAAAAGTCATTTAAGACGTATTTCAAATACAAAAAGCGCCATAGCAAAAAGTGTAAAAGATCTTG
TTTATGATCAATATAAGCATATTATTACCATGAAAGGACAAGAGCTTACTTTAACTAATGCTGAATTTGATATTTTAAGC
TATTTGATTAAAAAAGAGGGTGGAGTGGTAAGTCGTGAAGAGCTTGTTTATAATTGTTCTTCTATTAGTGAGGATTCTAG
TAATAAAAGTATAGATGTTATTATCAGTAGAATTCGTCAAAAGATGGGAGATGATCCAAAAACTCCAAAATATATTCACT
CTATACGTGGAATAGGTTATAAGCTTACTCAATGA

Upstream 100 bases:

>100_bases
TGCGACTTTGCTTGTGCTTAAATAAAAATAACGGAAGGATTTTCCTTTCGTTATAAATTTTAGTTTAAAATTAAAATTAA
GTTTAAAATAAAGGAAAACT

Downstream 100 bases:

>100_bases
ATAAATCTTCGATTTTTTATACTATAACTTTTATTTTTATTTTTGCTGGGGTTAGTGTTATACTTGGCTTTTTGTGGCTT
ATAGAATACGATCAGCAAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTNILMIEDDLELAEITAEYLEKFDMKVDIAHEPYIGLSKLALKEYQLIILDLSLPGLDGLEVCEEIRKKYDTPIIVSSA
RHDITDKVNALELGADDYLPKPYNPKELQARIKSHLRRISNTKSAIAKSVKDLVYDQYKHIITMKGQELTLTNAEFDILS
YLIKKEGGVVSREELVYNCSSISEDSSNKSIDVIISRIRQKMGDDPKTPKYIHSIRGIGYKLTQ

Sequences:

>Translated_224_residues
MTNILMIEDDLELAEITAEYLEKFDMKVDIAHEPYIGLSKLALKEYQLIILDLSLPGLDGLEVCEEIRKKYDTPIIVSSA
RHDITDKVNALELGADDYLPKPYNPKELQARIKSHLRRISNTKSAIAKSVKDLVYDQYKHIITMKGQELTLTNAEFDILS
YLIKKEGGVVSREELVYNCSSISEDSSNKSIDVIISRIRQKMGDDPKTPKYIHSIRGIGYKLTQ
>Mature_223_residues
TNILMIEDDLELAEITAEYLEKFDMKVDIAHEPYIGLSKLALKEYQLIILDLSLPGLDGLEVCEEIRKKYDTPIIVSSAR
HDITDKVNALELGADDYLPKPYNPKELQARIKSHLRRISNTKSAIAKSVKDLVYDQYKHIITMKGQELTLTNAEFDILSY
LIKKEGGVVSREELVYNCSSISEDSSNKSIDVIISRIRQKMGDDPKTPKYIHSIRGIGYKLTQ

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35.9090909090909, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=33.6283185840708, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=35.7142857142857, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=33.6363636363636, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=32.7354260089686, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=32.7272727272727, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=36.036036036036, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=30.1724137931034, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=34.3612334801762, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=29.5154185022026, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790863, Length=190, Percent_Identity=32.1052631578947, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=27.8026905829596, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=173, Percent_Identity=33.5260115606936, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787229, Length=166, Percent_Identity=32.5301204819277, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI48994928, Length=115, Percent_Identity=37.3913043478261, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25478; Mature: 25346

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNILMIEDDLELAEITAEYLEKFDMKVDIAHEPYIGLSKLALKEYQLIILDLSLPGLDG
CCCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHEEEEEEEECCCCCCH
LEVCEEIRKKYDTPIIVSSARHDITDKVNALELGADDYLPKPYNPKELQARIKSHLRRIS
HHHHHHHHHHCCCCEEEECCCHHHHHCCHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
NTKSAIAKSVKDLVYDQYKHIITMKGQELTLTNAEFDILSYLIKKEGGVVSREELVYNCS
HHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHH
SISEDSSNKSIDVIISRIRQKMGDDPKTPKYIHSIRGIGYKLTQ
HCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCC
>Mature Secondary Structure 
TNILMIEDDLELAEITAEYLEKFDMKVDIAHEPYIGLSKLALKEYQLIILDLSLPGLDG
CCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHEEEEEEEECCCCCCH
LEVCEEIRKKYDTPIIVSSARHDITDKVNALELGADDYLPKPYNPKELQARIKSHLRRIS
HHHHHHHHHHCCCCEEEECCCHHHHHCCHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
NTKSAIAKSVKDLVYDQYKHIITMKGQELTLTNAEFDILSYLIKKEGGVVSREELVYNCS
HHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHH
SISEDSSNKSIDVIISRIRQKMGDDPKTPKYIHSIRGIGYKLTQ
HCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA