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The map label for this gene is sasA [H]

Identifier: 57238094

GI number: 57238094

Start: 1271933

End: 1273123

Strand: Reverse

Name: sasA [H]

Synonym: CJE1357

Alternate gene names: 57238094

Gene position: 1273123-1271933 (Counterclockwise)

Preceding gene: 57238095

Following gene: 57238091

Centisome position: 71.61

GC content: 27.04

Gene sequence:

>1191_bases
ATGGCTAAAAAAGTCATTAGGCAAATTTTATTAATCTACCTAACAACTACAGGTATTTTTTTAACTATTTTTTTTGCATT
ATGGTATCAAAAATTATATGAAGAATTAGTTGTTTTAAAGGGTGCCACTTTGAGAGAAAATCATAGAAACATTGTTATAA
GCATCTTAAATTCTCGTTTTACCCCTATAGATATAAGTGCAAAAAATATTGCTCAAAGCACAGCACTAAAATTTGCTATA
TTTGATGCTAAAAAGATTGTTTTTAGTAATATAGATTTTGATTTAAGAAAGGCAAAGATAGAGCTTAAAGGTAGAGGTAT
TTGTGATAATAAGGTTTTTTTCCTTGCTCCTATGAGTGCAGATCATTATTTTTTAAGACATGCTAGCAATGAAGAAGTAA
ATACTAACGATGGTTTGCAAATTTTAATACAGGGTGAAGATGTTGGCAAAGATCTTTTTTGGATTAGAACGAAAGTTTTT
AGTTTTGCTATTATGGCTTTTTGCATATTGGGTTTAATATCTTATATTTTAGTAAAAATTGCTCTAAAGCCTTTGGAGGA
TAAAATCAGCACACTAAATCGTTTTATTAAAGATTCAACTCATGAACTCAATACCCCATTAAGTGTTATTTTGATGAGTA
TAGAACAACTTGAGCATCAAAATTTAGGAGATAATACTAAATTTACAAGGATTAAGCTTGCTGCAAAAAGTTTATCTCAA
GTGTACTCTGATCTTGTTTTTTATAATTTCCCTAATACCTTAGAAACAGAAAAACAAAAATTTGATTTAAGAATACTACT
TGAAGAAAGATTGGAATATTTTAAAGTATTTTTTGAGCAAAAAAAAATTACACTAAAGCTTGATTTAAATCAAGCAAATA
TTTTTGCTCCTAAAAGTCAAATTTCTAAATTGATTGATAATCTTATAAGCAATGCTATTAAATACAATAAAAAAGGTGGA
GTAATTTCTATAATTTTAAAAGCCAATTTTTTAAGTATTGCGGATACAGGTTGTGGAATTTCAAAGTCAAATTTAAATCA
TATTTTTGATAGATATACAAGATTTAATACCGATCAAGGAGGATTTGGTATAGGGCTTTCTTTGGTAAAAAAAGTTTGTG
ATGATAATGATATTAAGATTATTTGCGAATCTGTAGAAAATCAAGGGAGTGTTTTTAAATTAAATTGGTAA

Upstream 100 bases:

>100_bases
GAGGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCA
AAGAGGCAGGGGATATTGCT

Downstream 100 bases:

>100_bases
TCAGCAAGGAAAATCCTTGCTGATAAGAGGTTAGAGCAGATATTACATCATTCCGCCCATGCCACCCATTCCTCCCATAC
CGCTCATATCTGGCATAGTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAKKVIRQILLIYLTTTGIFLTIFFALWYQKLYEELVVLKGATLRENHRNIVISILNSRFTPIDISAKNIAQSTALKFAI
FDAKKIVFSNIDFDLRKAKIELKGRGICDNKVFFLAPMSADHYFLRHASNEEVNTNDGLQILIQGEDVGKDLFWIRTKVF
SFAIMAFCILGLISYILVKIALKPLEDKISTLNRFIKDSTHELNTPLSVILMSIEQLEHQNLGDNTKFTRIKLAAKSLSQ
VYSDLVFYNFPNTLETEKQKFDLRILLEERLEYFKVFFEQKKITLKLDLNQANIFAPKSQISKLIDNLISNAIKYNKKGG
VISIILKANFLSIADTGCGISKSNLNHIFDRYTRFNTDQGGFGIGLSLVKKVCDDNDIKIICESVENQGSVFKLNW

Sequences:

>Translated_396_residues
MAKKVIRQILLIYLTTTGIFLTIFFALWYQKLYEELVVLKGATLRENHRNIVISILNSRFTPIDISAKNIAQSTALKFAI
FDAKKIVFSNIDFDLRKAKIELKGRGICDNKVFFLAPMSADHYFLRHASNEEVNTNDGLQILIQGEDVGKDLFWIRTKVF
SFAIMAFCILGLISYILVKIALKPLEDKISTLNRFIKDSTHELNTPLSVILMSIEQLEHQNLGDNTKFTRIKLAAKSLSQ
VYSDLVFYNFPNTLETEKQKFDLRILLEERLEYFKVFFEQKKITLKLDLNQANIFAPKSQISKLIDNLISNAIKYNKKGG
VISIILKANFLSIADTGCGISKSNLNHIFDRYTRFNTDQGGFGIGLSLVKKVCDDNDIKIICESVENQGSVFKLNW
>Mature_395_residues
AKKVIRQILLIYLTTTGIFLTIFFALWYQKLYEELVVLKGATLRENHRNIVISILNSRFTPIDISAKNIAQSTALKFAIF
DAKKIVFSNIDFDLRKAKIELKGRGICDNKVFFLAPMSADHYFLRHASNEEVNTNDGLQILIQGEDVGKDLFWIRTKVFS
FAIMAFCILGLISYILVKIALKPLEDKISTLNRFIKDSTHELNTPLSVILMSIEQLEHQNLGDNTKFTRIKLAAKSLSQV
YSDLVFYNFPNTLETEKQKFDLRILLEERLEYFKVFFEQKKITLKLDLNQANIFAPKSQISKLIDNLISNAIKYNKKGGV
ISIILKANFLSIADTGCGISKSNLNHIFDRYTRFNTDQGGFGIGLSLVKKVCDDNDIKIICESVENQGSVFKLNW

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=204, Percent_Identity=26.9607843137255, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=25, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 45237; Mature: 45106

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKVIRQILLIYLTTTGIFLTIFFALWYQKLYEELVVLKGATLRENHRNIVISILNSRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
TPIDISAKNIAQSTALKFAIFDAKKIVFSNIDFDLRKAKIELKGRGICDNKVFFLAPMSA
CEEECCHHHHHHHHHHEEEEECHHHHHEECCCCEEEEEEEEECCCCCCCCCEEEEEECCC
DHYFLRHASNEEVNTNDGLQILIQGEDVGKDLFWIRTKVFSFAIMAFCILGLISYILVKI
CCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKPLEDKISTLNRFIKDSTHELNTPLSVILMSIEQLEHQNLGDNTKFTRIKLAAKSLSQ
HHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
VYSDLVFYNFPNTLETEKQKFDLRILLEERLEYFKVFFEQKKITLKLDLNQANIFAPKSQ
HHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCHHH
ISKLIDNLISNAIKYNKKGGVISIILKANFLSIADTGCGISKSNLNHIFDRYTRFNTDQG
HHHHHHHHHHHHHHCCCCCCEEEEEEEECEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
GFGIGLSLVKKVCDDNDIKIICESVENQGSVFKLNW
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECC
>Mature Secondary Structure 
AKKVIRQILLIYLTTTGIFLTIFFALWYQKLYEELVVLKGATLRENHRNIVISILNSRF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
TPIDISAKNIAQSTALKFAIFDAKKIVFSNIDFDLRKAKIELKGRGICDNKVFFLAPMSA
CEEECCHHHHHHHHHHEEEEECHHHHHEECCCCEEEEEEEEECCCCCCCCCEEEEEECCC
DHYFLRHASNEEVNTNDGLQILIQGEDVGKDLFWIRTKVFSFAIMAFCILGLISYILVKI
CCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKPLEDKISTLNRFIKDSTHELNTPLSVILMSIEQLEHQNLGDNTKFTRIKLAAKSLSQ
HHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
VYSDLVFYNFPNTLETEKQKFDLRILLEERLEYFKVFFEQKKITLKLDLNQANIFAPKSQ
HHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCHHH
ISKLIDNLISNAIKYNKKGGVISIILKANFLSIADTGCGISKSNLNHIFDRYTRFNTDQG
HHHHHHHHHHHHHHCCCCCCEEEEEEEECEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
GFGIGLSLVKKVCDDNDIKIICESVENQGSVFKLNW
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA