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The map label for this gene is gmhB [H]

Identifier: 57238027

GI number: 57238027

Start: 1205493

End: 1206020

Strand: Reverse

Name: gmhB [H]

Synonym: CJE1288

Alternate gene names: 57238027

Gene position: 1206020-1205493 (Counterclockwise)

Preceding gene: 57238029

Following gene: 57238026

Centisome position: 67.84

GC content: 25.0

Gene sequence:

>528_bases
ATGTTTTTTATGAAAACAAAAGCATTATTTTTAGATAGAGACGGTGTGATTAATATAGATAAAAAATATGTCTATAAAAT
AGAAGATTTTGAATTTTGTGATGGAATTTTTGAACTTTGTAGATATTTTTTAGCTAAAAAATATTTGCTTTTTATAGCGA
CAAATCAATCAGGCATTGCAAGAGGATATTATAAGGAAAGTGATTTTTTTAAGCTTTGTGATTATATGCTTAAAGAATTT
ACTAAACAAGGTATAAAAATTGATAAAATTTATCATTGTCCGCATTTAGAAGGTTGTGAATGTCGCAAACCTAAAGCAGG
AATGCTTTTAAAAGCAAAAGATGAGTTTAATTTAGATATGAAAAATTCTATTTTTATCGGAGATAATCTAAGCGATATGC
AAGCAGGGTTAAATGCTAATATTGGCACTTTGGTTTTAGTAAATGAAGAAAAAAAAGAAGGCGATTTTTTTAGACAATTT
AAAAATTTAAAAGAAATTTTGAGTTTTTTTAAAGAAAAGGACATTTAA

Upstream 100 bases:

>100_bases
GTAAAAATTAGATTGCCAGATATTATATATCTTTATTTTTATAAAAATCTTAAGAAAATAAAGATAATGTTTATTTTCTT
TTCAAAAAAGCTATATTATA

Downstream 100 bases:

>100_bases
ATGAGAGTAGCAATCACAGGTGGTGCAGGATTTATAGGTTCGCAACTGGCTTTAAATTTGCAAGAAAAACATGAAATTTT
AATCATTGATAAAATGCGTA

Product: hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MFFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLAKKYLLFIATNQSGIARGYYKESDFFKLCDYMLKEF
TKQGIKIDKIYHCPHLEGCECRKPKAGMLLKAKDEFNLDMKNSIFIGDNLSDMQAGLNANIGTLVLVNEEKKEGDFFRQF
KNLKEILSFFKEKDI

Sequences:

>Translated_175_residues
MFFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLAKKYLLFIATNQSGIARGYYKESDFFKLCDYMLKEF
TKQGIKIDKIYHCPHLEGCECRKPKAGMLLKAKDEFNLDMKNSIFIGDNLSDMQAGLNANIGTLVLVNEEKKEGDFFRQF
KNLKEILSFFKEKDI
>Mature_175_residues
MFFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLAKKYLLFIATNQSGIARGYYKESDFFKLCDYMLKEF
TKQGIKIDKIYHCPHLEGCECRKPKAGMLLKAKDEFNLDMKNSIFIGDNLSDMQAGLNANIGTLVLVNEEKKEGDFFRQF
KNLKEILSFFKEKDI

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=157, Percent_Identity=43.312101910828, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082027, Length=146, Percent_Identity=32.1917808219178, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20587; Mature: 20587

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLAKKYLLFIATNQSGIA
CCEEECEEEEECCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
RGYYKESDFFKLCDYMLKEFTKQGIKIDKIYHCPHLEGCECRKPKAGMLLKAKDEFNLDM
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCC
KNSIFIGDNLSDMQAGLNANIGTLVLVNEEKKEGDFFRQFKNLKEILSFFKEKDI
CCCEEECCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLAKKYLLFIATNQSGIA
CCEEECEEEEECCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
RGYYKESDFFKLCDYMLKEFTKQGIKIDKIYHCPHLEGCECRKPKAGMLLKAKDEFNLDM
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCC
KNSIFIGDNLSDMQAGLNANIGTLVLVNEEKKEGDFFRQFKNLKEILSFFKEKDI
CCCEEECCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204; 12101286 [H]