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The map label for this gene is yleA [C]

Identifier: 57237831

GI number: 57237831

Start: 1013733

End: 1014983

Strand: Reverse

Name: yleA [C]

Synonym: CJE1086

Alternate gene names: 57237831

Gene position: 1014983-1013733 (Counterclockwise)

Preceding gene: 57237832

Following gene: 57237830

Centisome position: 57.09

GC content: 30.86

Gene sequence:

>1251_bases
TTGAAAGAAAAAGTTTTTTTTAAAACCTTTGGATGTCGCACAAATATTTATGATACAGAGCTTTTAAAAAGTTATGTAAA
AGATTATGAGATTATAAATGATGAGAATAAAGCACAAATTATCGTTGTAAATTCTTGCACGGTTACAAATGGAGCTGATA
GCGGAATAAAGTCTTATGTAAATACCATGCAAAAAAAAGGCATTAAAGTTATACTTACAGGTTGTGGTGCTGTAAGCAAA
GGTAAGGAGCTTTTAGATAAAAAGCAAGTTTTTGGAGTGCTTGGAGCGTCAAATAAAGATAAAATCAATGAATTTTTAGG
AGCAAAGACAAGTTTTTATGAACTTGGAAATTTAAATTTTATTGATAAAGATATAGTTTGTGAGTATGAAAATCATACCA
AAGCTTTTGTGAAAATTCAAGAAGGTTGTGATTTTGCTTGTTCTTATTGTATTATTCCTAGCGTGAGGGGAAAATCAAGA
AGCGTGGATGAAAAAGCTCTTTTAAAACAGGTTGAAATTTTGGGAGCTAATGGTTATAGTGAAATTGTTTTAACAGGGAC
TAATATAGGTTCATATGGGCTTAAAAATGGCACAACCCTAGGCAAGCTTTTGCAAAAAATGGGACAAATTTTAGGTATAA
AACGCATAAGGTTAGGTAGTTTAGAACCTGCACAGCTTGATGAAAGTTTTTTAGAAATCTTAGATGAAGCTTGGCTTGAA
AGGCATTTACATATTGCATTGCAACATACAAGTGAAAAAATGCTTCGTATAATGAGAAGAAGATCACATACGGATAATGA
TTTAAAGCTTTTTAATACTATAGCAAGCAAAGGATATGCTTTAGGGACGGATTTTATAGTAGCTCATCCAGGCGAGAGTG
AAGAGCTATGGCAAGAAGCTTTAAGAAATTTTAAAGAATTTCCACTCACTCATATCCATGCTTTTATTTTTAGCCCTAGA
AACAACACGCATTCTGCTACCATGAAAGATGTGATAAATGGAACTTTAGCTAAAGAAAGGCTAAACACTTTAAAATCCAT
AGTAGAAAAAAATAATTATGAATTTAGGAAAAAAAATCAAGTTTCACTTGAAGTTTTGGTAGAAAATCAAAAAGATGGTT
TTTTTGAGGGTTATGATCAGTTTTTTAATAAGATCAAAATTAAAAGTGATAAAGATATAGCTAAAGAATGGATCGTTATA
TCTGAATATGAAGTACAAGAAAAGTCTAACTTTACAAATTTAAAAGGCTAG

Upstream 100 bases:

>100_bases
AAATTGCTTATCCATCGCAAAATTTATATTTAGGAAATTTAAATCAAAATCATTTTGAACAACATCATGAAAATATGTAT
TTTCATGCAAGGAATAAGGA

Downstream 100 bases:

>100_bases
ATAATGAAAAATAAAAAGATAATTTTAGCATCTTTTATGGTTTTATGTATGCTTTTGGGAATTTTATATTTTAAAAATGA
ACCTAAATATATAGATGAAA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMQKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQILGIKRIRLGSLEPAQLDESFLEILDEAWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALRNFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKIKIKSDKDIAKEWIVI
SEYEVQEKSNFTNLKG

Sequences:

>Translated_416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMQKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQILGIKRIRLGSLEPAQLDESFLEILDEAWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALRNFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKIKIKSDKDIAKEWIVI
SEYEVQEKSNFTNLKG
>Mature_416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMQKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQILGIKRIRLGSLEPAQLDESFLEILDEAWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALRNFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKIKIKSDKDIAKEWIVI
SEYEVQEKSNFTNLKG

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=424, Percent_Identity=24.5283018867925, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI28872784, Length=409, Percent_Identity=24.4498777506112, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI28872782, Length=409, Percent_Identity=24.4498777506112, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1786882, Length=392, Percent_Identity=25.5102040816327, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787057, Length=387, Percent_Identity=26.3565891472868, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17553146, Length=384, Percent_Identity=23.9583333333333, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71996771, Length=291, Percent_Identity=25.4295532646048, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356207, Length=403, Percent_Identity=25.5583126550869, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19922432, Length=371, Percent_Identity=23.989218328841, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47163; Mature: 47163

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHH
NTMQKKGIKVILTGCGAVSKGKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNF
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCE
IDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSRSVDEKALLKQVEILGANGYS
ECCCCEEEECCCCEEEEEEECCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
EIVLTGTNIGSYGLKNGTTLGKLLQKMGQILGIKRIRLGSLEPAQLDESFLEILDEAWLE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHH
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEECCCCCHHHHHHH
LRNFKEFPLTHIHAFIFSPRNNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQ
HHHHHHCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLEVLVENQKDGFFEGYDQFFNKIKIKSDKDIAKEWIVISEYEVQEKSNFTNLKG
CEEEEEEECCCCCCHHHHHHHHHHEECCCCHHHHHHCEEEECEEHHHCCCCCCCCC
>Mature Secondary Structure
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHH
NTMQKKGIKVILTGCGAVSKGKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNF
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCE
IDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSRSVDEKALLKQVEILGANGYS
ECCCCEEEECCCCEEEEEEECCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
EIVLTGTNIGSYGLKNGTTLGKLLQKMGQILGIKRIRLGSLEPAQLDESFLEILDEAWLE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHH
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEECCCCCHHHHHHH
LRNFKEFPLTHIHAFIFSPRNNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQ
HHHHHHCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLEVLVENQKDGFFEGYDQFFNKIKIKSDKDIAKEWIVISEYEVQEKSNFTNLKG
CEEEEEEECCCCCCHHHHHHHHHHEECCCCHHHHHHCEEEECEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]