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The map label for this gene is nudF [H]

Identifier: 55980832

GI number: 55980832

Start: 824339

End: 824887

Strand: Reverse

Name: nudF [H]

Synonym: TTHA0863

Alternate gene names: 55980832

Gene position: 824887-824339 (Counterclockwise)

Preceding gene: 55980833

Following gene: 55980831

Centisome position: 44.59

GC content: 68.49

Gene sequence:

>549_bases
ATGAGCCCCTGGGAGCGCATCCTCCTAGAGGAGATCCTCTCCGAGCCCGTCCGCCTGGTGAAGGAACGGGTACGGACGCA
CACGGGCCGGGAGCTCACCTACGTCTACCGCCCGGGCCCCGTGGCCGCAAGCTTCGTCCTCCCCGTGACGGAGAGGGGCA
CGGCCCTCCTCGTCCGCCAGTACCGCCATCCCACGGGCAAGTTCCTCCTGGAGGTTCCGGCGGGGAAGGTGGACGAGGGG
GAAACCCCGGAAGCGGCGGCGAGGCGGGAGCTAAGGGAGGAGGTGGGGGCCGAGGCGGAAACCCTCATCCCCCTGCCCTC
CTTCCACCCCCAGCCCTCCTTCACGGCGGTGGTCTTTCACCCCTTCCTCGCCCTCAAGGCCCGGGTGGTGACCCCGCCCA
CGCTGGAAGAGGGAGAGCTTCTGGAGAGCCTGGAGCTTCCCCTTACCGAGGTCTACGCCCTCCTCGCCAAAGGCGAGATC
CAGGACGCCTCCACCGCCCTCACCCTCTTCTACGCGGAACCTCACCTGAAGCGCTTGGGCCTGCTCTAA

Upstream 100 bases:

>100_bases
AGTTCAAAAACCCCCTCGCGGCCATCGGGGTGGTCACCAAGGCCCTGGGGCCCAAGGCCCCGGGGGAGAAGGTGCGCAAG
GTCATCGAGCGCCTCACGCG

Downstream 100 bases:

>100_bases
TCCCGTACCGCAAAGGGCGCCTAGGCGCTTCCCGGGCCGGCGGGGGTATAAAAGCCGAGGCCTGGCGCATAAACTCGGGC
TAGGATCCGCCTCCTTTCCC

Product: MutT/nudix family protein

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQYRHPTGKFLLEVPAGKVDEG
ETPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFHPFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEI
QDASTALTLFYAEPHLKRLGLL

Sequences:

>Translated_182_residues
MSPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQYRHPTGKFLLEVPAGKVDEG
ETPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFHPFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEI
QDASTALTLFYAEPHLKRLGLL
>Mature_181_residues
SPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQYRHPTGKFLLEVPAGKVDEGE
TPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFHPFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEIQ
DASTALTLFYAEPHLKRLGLL

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI37594464, Length=162, Percent_Identity=31.4814814814815, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 20312; Mature: 20181

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHH
YRHPTGKFLLEVPAGKVDEGETPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFH
HCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHH
PFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEIQDASTALTLFYAEPHLKRLG
HHHHHHEEECCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHC
LL
CC
>Mature Secondary Structure 
SPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHH
YRHPTGKFLLEVPAGKVDEGETPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFH
HCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHH
PFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEIQDASTALTLFYAEPHLKRLG
HHHHHHEEECCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHC
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]