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The map label for this gene is hhoB [H]

Identifier: 55980738

GI number: 55980738

Start: 735482

End: 736483

Strand: Reverse

Name: hhoB [H]

Synonym: TTHA0769

Alternate gene names: 55980738

Gene position: 736483-735482 (Counterclockwise)

Preceding gene: 55980739

Following gene: 55980733

Centisome position: 39.82

GC content: 74.85

Gene sequence:

>1002_bases
ATGGCCCGGCTCCGGCTAGGCCTCCTCGGGCTTCTCCTCCTCGCGGCCTTCCTCGCCTGGCGGGCCGCCCCTGAGGTCTT
CTGGACCCTCCCCGCCGGGGCGGAGGGCGAGGCCCTGGAGCGGGTCTACCGGGAGGCCCACCCCGCCGTCTTCCGGGTGG
AGGTGGCGGAAGGCCCCCGGGGCACGGGCTTTTTCGTGGGCAAGGACGAGGCCCTCACCGCCTACCACGTGGTGGCCGGG
AAGCGGGAGGTCGTCCTCTACACCGCCGCGGGGACGCGCCTCAAGGCCCGGGTCGTGGGCTTTTCCGAACCCCGGGACCT
GGCCTACCTGAAGGCGGAGGGGGAAGGCCCCAGGGCCCTCCCCCTGGGCCCCCTCACCCCTCCCCGCCCTGGGGAGGCCG
TCCTCCACATCGGGAACGGCCGGGGCGAGTTCCTCGCCCCTAGGTACGGCCGCGTCCTCCGCCTCGAGGCCTCCCCCTCC
CCCTTCCTTCCCCAAGGCCTTGTGGAAACCTCCCTCCCCCTCGCTCCCGGGGACTCCGGGGGGCCCGTCCTCAACCGGGA
GGGGAGGGTCCTGGGGGTGGCCGTGGCCATCGGGGCCACGGAGGAGGGCTTCCGCGGCTACTTCACCCCCCTCTTCGGCT
GGGAAAGGACCCTGGAGGCCCTCCGGGCGGGCCTCGAGGAGTCCTGGCCCTACCTGGGCCTGAGGGGGCCCAGGGGGCTC
ACCCCGGAGCTTGCCCGGGAACTGGGCCTGCCCCCGGGCGGGGTCCTGGTGGGCGAGGTGGTCCCGGGCGGGGCGGCCCA
CAGGGCGGGGCTTAGGGGGGTGGAGTCGGGCGGCGTGCCGGACGTGATCCTAGAGGTCAACGGCGTCCCCGTGAACGCCT
TTGAGGACCTCCTCCGGGAGGTGCGCCGCTACAGGGTGGGGGACAGGGTCCGGCTCACGGTGCGGCGGGGAGGCCAGGTC
TTCCCGGTGGAGGTGGTCCTCGCCCCCTTCCCCGGGCGCTAG

Upstream 100 bases:

>100_bases
GAGGAGGTGGGCGAGGTCCTGAAGCTCCTCCTCCTCCCCCCTCCCCCACCCCCGGCGGTCCAGCCGGACCGCCCCCAGCC
CGGCGTGGGCGCTTAGGACC

Downstream 100 bases:

>100_bases
CGGCCGTACACCACGCTCGGAAGCCAGGTGGCCAGCCCCGGGAAAAGCATCACCAAGGCCAGCCCCACGAGCTGGAGGAA
GAGGAAGGGAAGGGCAGCTT

Product: periplasmic serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MARLRLGLLGLLLLAAFLAWRAAPEVFWTLPAGAEGEALERVYREAHPAVFRVEVAEGPRGTGFFVGKDEALTAYHVVAG
KREVVLYTAAGTRLKARVVGFSEPRDLAYLKAEGEGPRALPLGPLTPPRPGEAVLHIGNGRGEFLAPRYGRVLRLEASPS
PFLPQGLVETSLPLAPGDSGGPVLNREGRVLGVAVAIGATEEGFRGYFTPLFGWERTLEALRAGLEESWPYLGLRGPRGL
TPELARELGLPPGGVLVGEVVPGGAAHRAGLRGVESGGVPDVILEVNGVPVNAFEDLLREVRRYRVGDRVRLTVRRGGQV
FPVEVVLAPFPGR

Sequences:

>Translated_333_residues
MARLRLGLLGLLLLAAFLAWRAAPEVFWTLPAGAEGEALERVYREAHPAVFRVEVAEGPRGTGFFVGKDEALTAYHVVAG
KREVVLYTAAGTRLKARVVGFSEPRDLAYLKAEGEGPRALPLGPLTPPRPGEAVLHIGNGRGEFLAPRYGRVLRLEASPS
PFLPQGLVETSLPLAPGDSGGPVLNREGRVLGVAVAIGATEEGFRGYFTPLFGWERTLEALRAGLEESWPYLGLRGPRGL
TPELARELGLPPGGVLVGEVVPGGAAHRAGLRGVESGGVPDVILEVNGVPVNAFEDLLREVRRYRVGDRVRLTVRRGGQV
FPVEVVLAPFPGR
>Mature_332_residues
ARLRLGLLGLLLLAAFLAWRAAPEVFWTLPAGAEGEALERVYREAHPAVFRVEVAEGPRGTGFFVGKDEALTAYHVVAGK
REVVLYTAAGTRLKARVVGFSEPRDLAYLKAEGEGPRALPLGPLTPPRPGEAVLHIGNGRGEFLAPRYGRVLRLEASPSP
FLPQGLVETSLPLAPGDSGGPVLNREGRVLGVAVAIGATEEGFRGYFTPLFGWERTLEALRAGLEESWPYLGLRGPRGLT
PELARELGLPPGGVLVGEVVPGGAAHRAGLRGVESGGVPDVILEVNGVPVNAFEDLLREVRRYRVGDRVRLTVRRGGQVF
PVEVVLAPFPGR

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=291, Percent_Identity=25.4295532646048, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789629, Length=280, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35597; Mature: 35465

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLRLGLLGLLLLAAFLAWRAAPEVFWTLPAGAEGEALERVYREAHPAVFRVEVAEGPR
CCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
GTGFFVGKDEALTAYHVVAGKREVVLYTAAGTRLKARVVGFSEPRDLAYLKAEGEGPRAL
CCEEEEECCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCCC
PLGPLTPPRPGEAVLHIGNGRGEFLAPRYGRVLRLEASPSPFLPQGLVETSLPLAPGDSG
CCCCCCCCCCCCEEEEEECCCCCEECCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCC
GPVLNREGRVLGVAVAIGATEEGFRGYFTPLFGWERTLEALRAGLEESWPYLGLRGPRGL
CCEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
TPELARELGLPPGGVLVGEVVPGGAAHRAGLRGVESGGVPDVILEVNGVPVNAFEDLLRE
CHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VRRYRVGDRVRLTVRRGGQVFPVEVVLAPFPGR
HHHHCCCCEEEEEEECCCEEEEEEEEEECCCCC
>Mature Secondary Structure 
ARLRLGLLGLLLLAAFLAWRAAPEVFWTLPAGAEGEALERVYREAHPAVFRVEVAEGPR
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
GTGFFVGKDEALTAYHVVAGKREVVLYTAAGTRLKARVVGFSEPRDLAYLKAEGEGPRAL
CCEEEEECCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCCC
PLGPLTPPRPGEAVLHIGNGRGEFLAPRYGRVLRLEASPSPFLPQGLVETSLPLAPGDSG
CCCCCCCCCCCCEEEEEECCCCCEECCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCC
GPVLNREGRVLGVAVAIGATEEGFRGYFTPLFGWERTLEALRAGLEESWPYLGLRGPRGL
CCEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
TPELARELGLPPGGVLVGEVVPGGAAHRAGLRGVESGGVPDVILEVNGVPVNAFEDLLRE
CHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VRRYRVGDRVRLTVRRGGQVFPVEVVLAPFPGR
HHHHCCCCEEEEEEECCCEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]