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The map label for this gene is rspB [C]

Identifier: 55980732

GI number: 55980732

Start: 729310

End: 730401

Strand: Reverse

Name: rspB [C]

Synonym: TTHA0763

Alternate gene names: 55980732

Gene position: 730401-729310 (Counterclockwise)

Preceding gene: 55980733

Following gene: 55980731

Centisome position: 39.49

GC content: 70.24

Gene sequence:

>1092_bases
ATGAAGGCCCTCCTCTACACCCCATCCCTCCCCCGCTTCTTCGGGGCGAGGCTTCTCGGTAAGCGCTTTCCCAGAAAGCT
CCTCCCCCTCAGGCTCGCCGAGGTCCCCCTCCCCGAACGGGAAGGCTTCCTGCGGGTCCGGGTGCGCCTAAGCGGGGTCT
GCGGCTCGGACCTCGCCCTCCTCTACGGGAAAAGCCCCCCCTCCCTAAGCCCCTTCTTCTCCTTCCCCGCGGTGCTGGGC
CACGAGATCCTGGGGGAACACGAGGGGGCTCTCGTGGCGGTGAACCCCCTCCTCGCCTGCGCCGACCGGGGGCTTCCCCC
CTGCCCTAGGTGCCAGGAGGGGGAGGAAGGGCTTTGCCAGAACGTGGCCGAGGGCCCCTTGGCCCCGGGGATGCTGGGCT
ACAACCGGGACCTCCCCGGGGGATGGGGGGAGTGGGTCCTGGCCCGCCCGGAGAGGCTCTACCCCATCCCCCCAGGCGTC
CCCGAGGAGCGGGCCGTCTTCGCCGAGCCTTTGGCGGTGGTCCTGAGGGGCTTAAACAAACTCAAGCCCTGGCCTGAGGA
GGTCCTGGTCCTGGGGATGGGCACCATCGGCCTCCTCGCGGTCAGGCTCCTACGGGCCCTGGGCTACGCGGGAAGGCTTC
TCGCCGTGGCCAAGTACCCCCACCAGGCGGAAAGGGCCAAGGCCTTCGGGGCAGACGGGGTCTACGGGAGCGCGAAGGAG
GCCCTTTTGGCGCGGGCCCGGCGCTACCGCTACCTCCTCTTTGAGGGCCATAGGGGCGGGTACGAGGCGGTGGTGGAGGC
CTCGGGAAGCGGCCGGGGCTTCCGGGAGGCCCTCGCCCTCGCCCGGGAAGGGGGGAAGGTGCTCCTCCTGGGAGCGCCGG
GGCTTGAGGTTGTGGACCTCTCCCCCTTCTGGTTTAAGGAGGTGGCCCTTTGGGGGAGCTACACCTACACCCGGGAGGAG
TTCCGGGAGGCGGTGGGGCTTCTCCCGGAGCTAGAGGGCCTGGAAAGCCTGGTGGGGGGCGTCTACCCCCTGGAGGCCTG
GCCCGAGGCCCTTGTGGCGAAGGGGAAGGCCCTCTTCCGGCCCAAAGGGTAG

Upstream 100 bases:

>100_bases
TGGTGGGGCTCAAGAACCACGGCCTCACCATCACCGGAAGAAGCCTGGACGAGATCCTGGAGCGCATAGAGGGCAAGCTC
ATCCGCACCGTGCCCATGGC

Downstream 100 bases:

>100_bases
GATGGAGGGCATGAAGGGCGCCGTCCTCATCACGGGAGCGAGCCGCGGCATCGGCGAGGCCACCGCCCGCCTCCTCCACG
CCAAGGGGTACCGGGTGGGC

Product: zinc-dependent dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKALLYTPSLPRFFGARLLGKRFPRKLLPLRLAEVPLPEREGFLRVRVRLSGVCGSDLALLYGKSPPSLSPFFSFPAVLG
HEILGEHEGALVAVNPLLACADRGLPPCPRCQEGEEGLCQNVAEGPLAPGMLGYNRDLPGGWGEWVLARPERLYPIPPGV
PEERAVFAEPLAVVLRGLNKLKPWPEEVLVLGMGTIGLLAVRLLRALGYAGRLLAVAKYPHQAERAKAFGADGVYGSAKE
ALLARARRYRYLLFEGHRGGYEAVVEASGSGRGFREALALAREGGKVLLLGAPGLEVVDLSPFWFKEVALWGSYTYTREE
FREAVGLLPELEGLESLVGGVYPLEAWPEALVAKGKALFRPKG

Sequences:

>Translated_363_residues
MKALLYTPSLPRFFGARLLGKRFPRKLLPLRLAEVPLPEREGFLRVRVRLSGVCGSDLALLYGKSPPSLSPFFSFPAVLG
HEILGEHEGALVAVNPLLACADRGLPPCPRCQEGEEGLCQNVAEGPLAPGMLGYNRDLPGGWGEWVLARPERLYPIPPGV
PEERAVFAEPLAVVLRGLNKLKPWPEEVLVLGMGTIGLLAVRLLRALGYAGRLLAVAKYPHQAERAKAFGADGVYGSAKE
ALLARARRYRYLLFEGHRGGYEAVVEASGSGRGFREALALAREGGKVLLLGAPGLEVVDLSPFWFKEVALWGSYTYTREE
FREAVGLLPELEGLESLVGGVYPLEAWPEALVAKGKALFRPKG
>Mature_363_residues
MKALLYTPSLPRFFGARLLGKRFPRKLLPLRLAEVPLPEREGFLRVRVRLSGVCGSDLALLYGKSPPSLSPFFSFPAVLG
HEILGEHEGALVAVNPLLACADRGLPPCPRCQEGEEGLCQNVAEGPLAPGMLGYNRDLPGGWGEWVLARPERLYPIPPGV
PEERAVFAEPLAVVLRGLNKLKPWPEEVLVLGMGTIGLLAVRLLRALGYAGRLLAVAKYPHQAERAKAFGADGVYGSAKE
ALLARARRYRYLLFEGHRGGYEAVVEASGSGRGFREALALAREGGKVLLLGAPGLEVVDLSPFWFKEVALWGSYTYTREE
FREAVGLLPELEGLESLVGGVYPLEAWPEALVAKGKALFRPKG

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787863, Length=270, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788407, Length=347, Percent_Identity=26.8011527377522, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI226510992, Length=310, Percent_Identity=27.4193548387097, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790718, Length=320, Percent_Identity=26.5625, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790045, Length=300, Percent_Identity=26, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788073, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788075, Length=339, Percent_Identity=23.3038348082596, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786825, Length=330, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082125, Length=318, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=345, Percent_Identity=24.9275362318841, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=325, Percent_Identity=25.5384615384615, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322619, Length=325, Percent_Identity=25.5384615384615, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=356, Percent_Identity=25, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 39438; Mature: 39438

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLYTPSLPRFFGARLLGKRFPRKLLPLRLAEVPLPEREGFLRVRVRLSGVCGSDLAL
CCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEE
LYGKSPPSLSPFFSFPAVLGHEILGEHEGALVAVNPLLACADRGLPPCPRCQEGEEGLCQ
EECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHH
NVAEGPLAPGMLGYNRDLPGGWGEWVLARPERLYPIPPGVPEERAVFAEPLAVVLRGLNK
HHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKPWPEEVLVLGMGTIGLLAVRLLRALGYAGRLLAVAKYPHQAERAKAFGADGVYGSAKE
CCCCHHHHEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHH
ALLARARRYRYLLFEGHRGGYEAVVEASGSGRGFREALALAREGGKVLLLGAPGLEVVDL
HHHHHHHHCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEC
SPFWFKEVALWGSYTYTREEFREAVGLLPELEGLESLVGGVYPLEAWPEALVAKGKALFR
CCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
PKG
CCC
>Mature Secondary Structure
MKALLYTPSLPRFFGARLLGKRFPRKLLPLRLAEVPLPEREGFLRVRVRLSGVCGSDLAL
CCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEE
LYGKSPPSLSPFFSFPAVLGHEILGEHEGALVAVNPLLACADRGLPPCPRCQEGEEGLCQ
EECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHH
NVAEGPLAPGMLGYNRDLPGGWGEWVLARPERLYPIPPGVPEERAVFAEPLAVVLRGLNK
HHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKPWPEEVLVLGMGTIGLLAVRLLRALGYAGRLLAVAKYPHQAERAKAFGADGVYGSAKE
CCCCHHHHEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHH
ALLARARRYRYLLFEGHRGGYEAVVEASGSGRGFREALALAREGGKVLLLGAPGLEVVDL
HHHHHHHHCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEC
SPFWFKEVALWGSYTYTREEFREAVGLLPELEGLESLVGGVYPLEAWPEALVAKGKALFR
CCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
PKG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]