BacMap

Definition	Thermus thermophilus HB8 chromosome, complete genome.
Accession	NC_006461
Length	1,849,742

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The map label for this gene is ydfG [C]

Identifier: 55980731

GI number: 55980731

Start: 728604

End: 729308

Strand: Reverse

Name: ydfG [C]

Synonym: TTHA0762

Alternate gene names: 55980731

Gene position: 729308-728604 (Counterclockwise)

Preceding gene: 55980732

Following gene: 55980730

Centisome position: 39.43

GC content: 72.48

Gene sequence:

>705_bases
ATGGAGGGCATGAAGGGCGCCGTCCTCATCACGGGAGCGAGCCGCGGCATCGGCGAGGCCACCGCCCGCCTCCTCCACGC
CAAGGGGTACCGGGTGGGCCTCATGGCCCGGGACGAAAAGAGGCTCCAGGCCCTCGCCGCCGAGCTGGAGGGGGCCCTAC
CCCTTCCCGGGGACGTCCGGGAGGAGGGGGACTGGGCCCGGGCCGTGGCCGCCATGGAGGAGGCCTTCGGGGAGCTTAGC
GCCCTGGTGAACAACGCCGGGGTCGGGGTGATGAAGCCCGTCCACGAGCTCACCCTGGAGGAGTGGCGGCTCGTGCTGGA
CACCAACCTCACGGGGGCCTTCCTCGGCATCCGCCACGCCGTCCCCGCCCTCCTGCGCCGGGGCGGGGGCACCATCGTCA
ACGTGGGGAGCCTCGCGGGGAAGAACCCCTTCAAGGGCGGGGCCGCCTACAACGCCAGCAAGTTCGGCCTTTTGGGCCTC
GCCGGGGCCGCCATGCTGGACCTCCGGGAGGCGAACGTCCGGGTGGTGAACGTCCTCCCGGGCTCCGTGGACACCGGCTT
CGCCGGGAACACCCCGGGCCAGGCCTGGAAGCTTAAGCCCGAGGACGTGGCCCAAGCGGTCCTCTTCGCCCTGGAGATGC
CCGGGCACGCCATGGTGAGCGAGATTGAGCTCCGGCCCACCCGGCCCACGTCCGGCCCGCGGTAA

Upstream 100 bases:

>100_bases
GAGGGCCTGGAAAGCCTGGTGGGGGGCGTCTACCCCCTGGAGGCCTGGCCCGAGGCCCTTGTGGCGAAGGGGAAGGCCCT
CTTCCGGCCCAAAGGGTAGG

Downstream 100 bases:

>100_bases
GGTGGAGGCATGGTGCCGCCCAAGCTCAAGCAGGCCCTGGAGCTTTTCAAAAGCCTTCCCAAGGAGCTCCGATCCCAGGT
GCTCCTGGAGTACGCGGCCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MEGMKGAVLITGASRGIGEATARLLHAKGYRVGLMARDEKRLQALAAELEGALPLPGDVREEGDWARAVAAMEEAFGELS
ALVNNAGVGVMKPVHELTLEEWRLVLDTNLTGAFLGIRHAVPALLRRGGGTIVNVGSLAGKNPFKGGAAYNASKFGLLGL
AGAAMLDLREANVRVVNVLPGSVDTGFAGNTPGQAWKLKPEDVAQAVLFALEMPGHAMVSEIELRPTRPTSGPR

Sequences:

>Translated_234_residues
MEGMKGAVLITGASRGIGEATARLLHAKGYRVGLMARDEKRLQALAAELEGALPLPGDVREEGDWARAVAAMEEAFGELS
ALVNNAGVGVMKPVHELTLEEWRLVLDTNLTGAFLGIRHAVPALLRRGGGTIVNVGSLAGKNPFKGGAAYNASKFGLLGL
AGAAMLDLREANVRVVNVLPGSVDTGFAGNTPGQAWKLKPEDVAQAVLFALEMPGHAMVSEIELRPTRPTSGPR
>Mature_234_residues
MEGMKGAVLITGASRGIGEATARLLHAKGYRVGLMARDEKRLQALAAELEGALPLPGDVREEGDWARAVAAMEEAFGELS
ALVNNAGVGVMKPVHELTLEEWRLVLDTNLTGAFLGIRHAVPALLRRGGGTIVNVGSLAGKNPFKGGAAYNASKFGLLGL
AGAAMLDLREANVRVVNVLPGSVDTGFAGNTPGQAWKLKPEDVAQAVLFALEMPGHAMVSEIELRPTRPTSGPR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=30.5785123966942, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI40254992, Length=230, Percent_Identity=33.4782608695652, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI32483357, Length=185, Percent_Identity=34.5945945945946, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=28.9592760180996, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=34.1836734693878, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=234, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI7705925, Length=222, Percent_Identity=31.981981981982, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723191, Length=172, Percent_Identity=34.3023255813954, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.4248704663212, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI126723750, Length=188, Percent_Identity=32.4468085106383, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4758504, Length=214, Percent_Identity=32.2429906542056, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI157739938, Length=229, Percent_Identity=27.9475982532751, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31542939, Length=188, Percent_Identity=32.9787234042553, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI40548397, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010158, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010156, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22758144, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=32.972972972973, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=32.6530612244898, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19743808, Length=213, Percent_Identity=31.4553990610329, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI59889578, Length=165, Percent_Identity=32.1212121212121, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=29.4605809128631, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI83715985, Length=228, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI150247226, Length=183, Percent_Identity=31.6939890710383, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI40254986, Length=171, Percent_Identity=30.4093567251462, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI224922801, Length=165, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4504505, Length=150, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI223718074, Length=211, Percent_Identity=32.2274881516588, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=233, Percent_Identity=33.0472103004292, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI2367175, Length=226, Percent_Identity=34.9557522123894, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788459, Length=201, Percent_Identity=30.8457711442786, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=178, Percent_Identity=32.0224719101124, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=30.6122448979592, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082100, Length=212, Percent_Identity=29.2452830188679, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=229, Percent_Identity=31.0043668122271, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789057, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082160, Length=181, Percent_Identity=28.1767955801105, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790717, Length=182, Percent_Identity=28.021978021978, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=219, Percent_Identity=30.1369863013699, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=234, Percent_Identity=28.6324786324786, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=32.620320855615, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=239, Percent_Identity=28.4518828451883, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=30.5699481865285, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=233, Percent_Identity=27.4678111587983, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=30.8900523560209, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=231, Percent_Identity=29.8701298701299, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=235, Percent_Identity=28.936170212766, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=183, Percent_Identity=26.775956284153, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=229, Percent_Identity=26.2008733624454, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=191, Percent_Identity=31.413612565445, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=186, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=191, Percent_Identity=30.8900523560209, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=29.718875502008, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=31.0880829015544, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=216, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=179, Percent_Identity=36.3128491620112, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=36.7567567567568, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281364494, Length=240, Percent_Identity=30.4166666666667, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641388, Length=241, Percent_Identity=31.9502074688797, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571387, Length=234, Percent_Identity=31.1965811965812, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21356301, Length=206, Percent_Identity=29.6116504854369, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.3664921465969, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357041, Length=183, Percent_Identity=32.2404371584699, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007234, Length=233, Percent_Identity=30.9012875536481, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643142, Length=182, Percent_Identity=35.1648351648352, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.4607329842932, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=27.8969957081545, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641232, Length=239, Percent_Identity=30.1255230125523, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648944, Length=233, Percent_Identity=27.8969957081545, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639444, Length=228, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648693, Length=243, Percent_Identity=27.9835390946502, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355889, Length=243, Percent_Identity=27.9835390946502, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640492, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=30.6122448979592, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663911, Length=238, Percent_Identity=28.9915966386555, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355631, Length=220, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI18859837, Length=161, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24493; Mature: 24493

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGMKGAVLITGASRGIGEATARLLHAKGYRVGLMARDEKRLQALAAELEGALPLPGDVR
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
EEGDWARAVAAMEEAFGELSALVNNAGVGVMKPVHELTLEEWRLVLDTNLTGAFLGIRHA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHH
VPALLRRGGGTIVNVGSLAGKNPFKGGAAYNASKFGLLGLAGAAMLDLREANVRVVNVLP
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCEEEEEEEC
GSVDTGFAGNTPGQAWKLKPEDVAQAVLFALEMPGHAMVSEIELRPTRPTSGPR
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCHHEHEEEECCCCCCCCCC
>Mature Secondary Structure
MEGMKGAVLITGASRGIGEATARLLHAKGYRVGLMARDEKRLQALAAELEGALPLPGDVR
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
EEGDWARAVAAMEEAFGELSALVNNAGVGVMKPVHELTLEEWRLVLDTNLTGAFLGIRHA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHH
VPALLRRGGGTIVNVGSLAGKNPFKGGAAYNASKFGLLGLAGAAMLDLREANVRVVNVLP
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCEEEEEEEC
GSVDTGFAGNTPGQAWKLKPEDVAQAVLFALEMPGHAMVSEIELRPTRPTSGPR
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCHHEHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]