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The map label for this gene is infC [H]

Identifier: 54295555

GI number: 54295555

Start: 3011843

End: 3012379

Strand: Reverse

Name: infC [H]

Synonym: lpl2642

Alternate gene names: 54295555

Gene position: 3012379-3011843 (Counterclockwise)

Preceding gene: 54295556

Following gene: 54295554

Centisome position: 90.04

GC content: 42.27

Gene sequence:

>537_bases
ATTAGTGCACCAACTAAGCGTGAAAATGATCGCGCACGAATTAATGAACAGATCACTGTACCTGAGGTACGCTTAATTGA
TGTCGATGGTAACCAGGCAGGAATTGTATCAACGCGAGAAGCGTTAAGGGCAGCAGAAGAAAGCGGATTGGATTTGGTGG
AAATATCTCCAACAGCCAAACCCCCTGTTTGTCGTATTATGGATTATGGTAAGTTTCTCTTTGAACTGAGTAAAAAACAA
GCTGAAGCAAGAAAGAAGCAAAAACAAATTCAGGTCAAAGAATTAAAATTCCGTCCTACGACGGAAGATGGAGATTATCA
GGTCAAGCTACGCAACCTGATCCGTTTCCTCAATCATGGTGATAAGGTCAAAATCACATTGCGTTTTCGCGGTCGTGAAA
TGGCTCATCAAGAACTCGGTATGAAGATTTTGGAACGTTTGCAAGCCGACACGGCGGATGTAGCTATAGTGGAGCAGCAT
GCAAAACGTGAAGGAAGACAATTACTGATGGTATTATCACCCAAAAAAACCAAGTAA

Upstream 100 bases:

>100_bases
TGACCTGGGTGTGATGACAATAGATACAATTTGTGATACCTTAACGCAAGAAATTATCCGTAAAGGATCAATATAAATAA
ACGAACTGGAGGATTAAACC

Downstream 100 bases:

>100_bases
CGAATGCGGAGTATATTGTTATGCCGAAGTTAAAGTCACATCGTGGAGCAGCTAAACGCTTCCGAAAGACAGCGAGTGGA
GCGATTAAACGTCGCGGCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSAPTKRENDRARINEQITVPEVRLIDVDGNQAGIVSTREALRAAEESGLDLVEISPTAKPPVCRIMDYGKFLFELSKKQ
AEARKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQH
AKREGRQLLMVLSPKKTK

Sequences:

>Translated_178_residues
MSAPTKRENDRARINEQITVPEVRLIDVDGNQAGIVSTREALRAAEESGLDLVEISPTAKPPVCRIMDYGKFLFELSKKQ
AEARKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQH
AKREGRQLLMVLSPKKTK
>Mature_177_residues
SAPTKRENDRARINEQITVPEVRLIDVDGNQAGIVSTREALRAAEESGLDLVEISPTAKPPVCRIMDYGKFLFELSKKQA
EARKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQHA
KREGRQLLMVLSPKKTK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=173, Percent_Identity=65.3179190751445, Blast_Score=207, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20389; Mature: 20258

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTKRENDRARINEQITVPEVRLIDVDGNQAGIVSTREALRAAEESGLDLVEISPTAK
CCCCCCCCCCHHHCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
PPVCRIMDYGKFLFELSKKQAEARKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCCCCEEEHHHHHHHHHCCC
DKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLLMVLSPKKTK
CEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure 
SAPTKRENDRARINEQITVPEVRLIDVDGNQAGIVSTREALRAAEESGLDLVEISPTAK
CCCCCCCCCHHHCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
PPVCRIMDYGKFLFELSKKQAEARKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCCCCEEEHHHHHHHHHCCC
DKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLLMVLSPKKTK
CEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA