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The map label for this gene is 54295359

Identifier: 54295359

GI number: 54295359

Start: 2784403

End: 2785533

Strand: Reverse

Name: 54295359

Synonym: lpl2444

Alternate gene names: NA

Gene position: 2785533-2784403 (Counterclockwise)

Preceding gene: 54295361

Following gene: 54295357

Centisome position: 83.26

GC content: 38.2

Gene sequence:

>1131_bases
ATGAAAGAAAAATACATCGGGCTTCATAAGATAGAACTAAATACCCCATGCCTTGTGATTGATTATGAAAAGCTGAAATA
CAACTTAAAAATGATGCAACAACATGGTTTCAAATGGGGTATAGGAATAAGGCCGCATTGTAAAACTCATAAATGTACTC
AAATCGCACGTTTACAACTTGAATATGGGGCAATAGGGATTTCTGCCGCCAAACTATCAGAGGCTGAAGTATTGGTATCC
AAACAAATCACGAATGTCTTAATCACTTCACCCATTGTATCGGAGGCCAAGTATTCAAGATTATTCAATTCTCTTAAATC
AGCGCCTGATTTAATGCTGGTTGTAGATGGCAAGGATAATATTCGCATGCTTAATGAGCTTGGAAAGTCGCTAAACCAGC
CAGTTTATGTTTTGCTTGATATCGATTCAGGTATTGGTCGAACGGGCATTAATCCCGAGGCAGCTTTGGAATATGGTCAT
TTTATCAATGGGATGAATTGGCTTAAGCTAAAAGGAATTCAATGTTATGCAGGCCACTTGCAACATATTCAAAACTATGA
AGAGAGAAAAGCATTTTCTCTACGTATTATGGAAATGGCCAGCAGGATTGTTAAGAGTTTTAGAGAAACCAATCTCCCTT
GTGAAATATTAACTGGCACCGGAACTGGTACTTTTGATATTGATGTCGAAGCAAGTGAAGTAACAGAAATCCAGCCTGGC
TCATATGCTGTAATGGATGTTGAGTATGGTTCAATTGGTTCAAAAAATACCCCATCAAGCTTTCAACTATTTAAAAACTC
GATGACTCTTTTAACGAGCGTGATAAGCAGTAATCGTAGAGAGCATGCCACTGTTGATGCAGGAACGAAATCGATTTATG
TCGATCCTCATCATAAACCACATATTATCAGTCATCCACGACTGGTTTATGACTGGAGTGGATTTGGAGATGAGCATGGC
AAGGTATTTTCTTGTGACGGAGGGGAACATTTTCTGCAAAATGGTGATGTTTTAGAGCTTATTGTTCCTCATTGTGATCC
GACAATAAACCTATATGATAAGTTCTATATCACAGAAAATAACGTCGTTATCGATATTTGGGATATCGACATGCGTGGAA
AGTCACAATAA

Upstream 100 bases:

>100_bases
TCATCTTTTAAAAAATAGTTTAATAAAAGCTTAAATTGTGGCAAACCTAAATAATTTATGTCATAAAACGCATTTATTTG
ACATTGTGATGAATTATCTC

Downstream 100 bases:

>100_bases
TCTATACTATTCAACCAGGTGTTTGAGTTTCATATTTTTGCTAAACAGGGGGAGGGCCACGACGCCCGATTAATCCCATA
ATAAGAAATATGACAAACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKEKYIGLHKIELNTPCLVIDYEKLKYNLKMMQQHGFKWGIGIRPHCKTHKCTQIARLQLEYGAIGISAAKLSEAEVLVS
KQITNVLITSPIVSEAKYSRLFNSLKSAPDLMLVVDGKDNIRMLNELGKSLNQPVYVLLDIDSGIGRTGINPEAALEYGH
FINGMNWLKLKGIQCYAGHLQHIQNYEERKAFSLRIMEMASRIVKSFRETNLPCEILTGTGTGTFDIDVEASEVTEIQPG
SYAVMDVEYGSIGSKNTPSSFQLFKNSMTLLTSVISSNRREHATVDAGTKSIYVDPHHKPHIISHPRLVYDWSGFGDEHG
KVFSCDGGEHFLQNGDVLELIVPHCDPTINLYDKFYITENNVVIDIWDIDMRGKSQ

Sequences:

>Translated_376_residues
MKEKYIGLHKIELNTPCLVIDYEKLKYNLKMMQQHGFKWGIGIRPHCKTHKCTQIARLQLEYGAIGISAAKLSEAEVLVS
KQITNVLITSPIVSEAKYSRLFNSLKSAPDLMLVVDGKDNIRMLNELGKSLNQPVYVLLDIDSGIGRTGINPEAALEYGH
FINGMNWLKLKGIQCYAGHLQHIQNYEERKAFSLRIMEMASRIVKSFRETNLPCEILTGTGTGTFDIDVEASEVTEIQPG
SYAVMDVEYGSIGSKNTPSSFQLFKNSMTLLTSVISSNRREHATVDAGTKSIYVDPHHKPHIISHPRLVYDWSGFGDEHG
KVFSCDGGEHFLQNGDVLELIVPHCDPTINLYDKFYITENNVVIDIWDIDMRGKSQ
>Mature_376_residues
MKEKYIGLHKIELNTPCLVIDYEKLKYNLKMMQQHGFKWGIGIRPHCKTHKCTQIARLQLEYGAIGISAAKLSEAEVLVS
KQITNVLITSPIVSEAKYSRLFNSLKSAPDLMLVVDGKDNIRMLNELGKSLNQPVYVLLDIDSGIGRTGINPEAALEYGH
FINGMNWLKLKGIQCYAGHLQHIQNYEERKAFSLRIMEMASRIVKSFRETNLPCEILTGTGTGTFDIDVEASEVTEIQPG
SYAVMDVEYGSIGSKNTPSSFQLFKNSMTLLTSVISSNRREHATVDAGTKSIYVDPHHKPHIISHPRLVYDWSGFGDEHG
KVFSCDGGEHFLQNGDVLELIVPHCDPTINLYDKFYITENNVVIDIWDIDMRGKSQ

Specific function: Catalyzes the reversible cleavage of D-theronine or D- allothreonine into glycine and acetaldehyde. Can also cleave D- beta-phenylserine, D-beta-hydroxy-alpha-aminovaleric acid, D-beta- 3,4-dihydroxyphenylserine and D-beta-3,4- methylenedioxyphenylserine

COG id: COG3616

COG function: function code E; Predicted amino acid aldolase or racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DSD1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001608 [H]

Pfam domain/function: PF01168 Ala_racemase_N [H]

EC number: =4.1.2.42 [H]

Molecular weight: Translated: 42282; Mature: 42282

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKYIGLHKIELNTPCLVIDYEKLKYNLKMMQQHGFKWGIGIRPHCKTHKCTQIARLQL
CCCCEEEEEEEEECCCEEEEEHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHEEEEEE
EYGAIGISAAKLSEAEVLVSKQITNVLITSPIVSEAKYSRLFNSLKSAPDLMLVVDGKDN
EECEEEEEHHHCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IRMLNELGKSLNQPVYVLLDIDSGIGRTGINPEAALEYGHFINGMNWLKLKGIQCYAGHL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECEEEHHHHH
QHIQNYEERKAFSLRIMEMASRIVKSFRETNLPCEILTGTGTGTFDIDVEASEVTEIQPG
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEHHHCCEECCC
SYAVMDVEYGSIGSKNTPSSFQLFKNSMTLLTSVISSNRREHATVDAGTKSIYVDPHHKP
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCC
HIISHPRLVYDWSGFGDEHGKVFSCDGGEHFLQNGDVLELIVPHCDPTINLYDKFYITEN
CEECCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCEEEEEECCCCCCEEEEEEEEEECC
NVVIDIWDIDMRGKSQ
CEEEEEEEECCCCCCC
>Mature Secondary Structure
MKEKYIGLHKIELNTPCLVIDYEKLKYNLKMMQQHGFKWGIGIRPHCKTHKCTQIARLQL
CCCCEEEEEEEEECCCEEEEEHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHEEEEEE
EYGAIGISAAKLSEAEVLVSKQITNVLITSPIVSEAKYSRLFNSLKSAPDLMLVVDGKDN
EECEEEEEHHHCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IRMLNELGKSLNQPVYVLLDIDSGIGRTGINPEAALEYGHFINGMNWLKLKGIQCYAGHL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECEEEHHHHH
QHIQNYEERKAFSLRIMEMASRIVKSFRETNLPCEILTGTGTGTFDIDVEASEVTEIQPG
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEHHHCCEECCC
SYAVMDVEYGSIGSKNTPSSFQLFKNSMTLLTSVISSNRREHATVDAGTKSIYVDPHHKP
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCC
HIISHPRLVYDWSGFGDEHGKVFSCDGGEHFLQNGDVLELIVPHCDPTINLYDKFYITEN
CEECCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCEEEEEECCCCCCEEEEEEEEEECC
NVVIDIWDIDMRGKSQ
CEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9642221 [H]