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The map label for this gene is nixA [H]

Identifier: 54295312

GI number: 54295312

Start: 2727452

End: 2728168

Strand: Reverse

Name: nixA [H]

Synonym: lpl2397

Alternate gene names: 54295312

Gene position: 2728168-2727452 (Counterclockwise)

Preceding gene: 54295315

Following gene: 54295311

Centisome position: 81.54

GC content: 37.24

Gene sequence:

>717_bases
TTGTTCACAGTCTTTAACATTAATAATGGCCCCATACTAATGAACGATTCAGGTTGGTTTTTGATTTCAACTGCTCTTTT
GCTTGGCATGCGTCATGGTTTTGATTTGGATCATCTGGCAACGATCGATGCGATAACTCGCACGGTTCGTTATAGACCTT
CTTTATCGCGCATGGTTGGCTTTTTGTTTTCACTAGGCCATGGTTTGGTAGTTATTATTGTGAGTTTGATCATTGGCGCG
GGTACTATTTCAGCGAGTACTCCTGAATGGTTAAATGAAGTGGGAAATATTGTATCAGTTACCTGTTTATTGTTATTTGG
GTTTTTAACTTTGTGGAATACGGTTCATTATTCATCTTCTGCCATCATACCAACCAACTTAAGGAGTTATTTATTCAGGA
AGCTTGCTGATAACAATGTACATCCTCTTATGATTCTTCTCATTGGTGCGTTGTTTGCCTTATCTTTTGATACGATTAGT
CAAATTGTATTGTTTTCACTTGCAGCCAGTGCTTTATCAGGTTTTCTATTTTCCGGGTTATTAGGTTTTGTTTTTATGCT
GGGAATGATGATGTCGGATGGATTAAATGGATTTTTTGTAGCAAGCTTGATTCGGCGTGCTGATGGGTTCTCATTACTTT
TCTCAAGATTAGTAGGATTTGGCATTGCTTTTTTTAGCATAGGTATTGCTATAATCAATTGCTGCAAATTGCTTTAA

Upstream 100 bases:

>100_bases
TATTAATGTACAAGACAAAAGATAGATAGCTTCATATGTTAACCTACTCTTGGAAGTTGAGTCCATTGAGGGTTATAAAA
ACAGTGAAAGTATTGGTATA

Downstream 100 bases:

>100_bases
ACAGGCTAAAAATGCATGAATTATGGTTATGTAAGCGTATTGTCGAGATTATCAAGCAACAAGCCACTGGCAATAAATGC
CGAAAGGTAAAGAAAATAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MFTVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYRPSLSRMVGFLFSLGHGLVVIIVSLIIGA
GTISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTIS
QIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIAFFSIGIAIINCCKLL

Sequences:

>Translated_238_residues
MFTVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYRPSLSRMVGFLFSLGHGLVVIIVSLIIGA
GTISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTIS
QIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIAFFSIGIAIINCCKLL
>Mature_238_residues
MFTVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYRPSLSRMVGFLFSLGHGLVVIIVSLIIGA
GTISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTIS
QIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIAFFSIGIAIINCCKLL

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 25919; Mature: 25919

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYRPSLSRMVG
CEEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FLFSLGHGLVVIIVSLIIGAGTISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSS
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALSGFLFSGL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIAFFSIGIAIINCCKLL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYRPSLSRMVG
CEEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FLFSLGHGLVVIIVSLIIGAGTISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSS
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALSGFLFSGL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIAFFSIGIAIINCCKLL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]