Click here to switch to the map view.

The map label for this gene is hypD [H]

Identifier: 54295307

GI number: 54295307

Start: 2722760

End: 2723866

Strand: Reverse

Name: hypD [H]

Synonym: lpl2392

Alternate gene names: 54295307

Gene position: 2723866-2722760 (Counterclockwise)

Preceding gene: 54295308

Following gene: 54295306

Centisome position: 81.41

GC content: 43.09

Gene sequence:

>1107_bases
GTGAAATACATAGAAGAGTTTCGTAACGGTGTTTACGCACAAGCCATTGTCAATGAAATTATTGCGACAGCAGATCCGCA
AAGACATTATCAGTTTATGGAGTTTTGCGGTGGCCACACGCATGCTATTCATCGTTATGGGATCCCGAGTTTGCTTCCCA
ACAATGTTGAAATGATTCATGGCCCCGGTTGTCCGGTTTGTGTTTTGCCTGTTGCGAGAATTGATAAGGCTATTGCGCTG
GCCTCGATGCCTCAAGTGATACTGTGCAGCTACGCTGACATGCTGCGAGTTCCGGGTACTGGACAAAGAAGTTTGTTAAC
CGCCAAAGCAGGCGGGGCTGATGTCAGGATGATTTACTCTGCGGATGATGCATTAAAAATCGCTCAGGAAAATCCCGATA
AAGACGTTGTATTTTTTGCTATAGGCTTTGAAACAACAACCCCTCCGACTGCTTTTGTCATCAAGCAAGCTAAAAAATTA
AACATCACTAATTTCAGTGTATTTTGTAACCATGTGTTAACTCCCATTGCTATGGATAGTTTGCTACAGGCCAATGAAGT
TGCCCTGGACGGCTTTGTTGGCCCAGCCCATGTCAGTATTGTGATAGGAAGCTATCCTTATGAGCATGTGTGTAAAAAAT
ACCAAAAGCCGATAGTGATATCAGGGTTTGAACCCTTGGATGTGTTGCATTCTATTCTCATGTTAATTCAACAATTGAAT
GAGGGGCGGTGTGAAGTGGAAATTCAATATACTCGTGCAGTGAATCGTACGGGTAATCTTTTGTCGCAACACATCATGGC
TGAAATCCTGGAAATACGGGATCGTTTTGAATGGCGTGGTTTGGGTTTTATTCCATCCAGCGCGTTAAAAATCAAAGAGT
CTTTTTCTGAATTTGATGCTGAGCAGCGTTTTGAATTACCTGATAGTGCAGCACAGGAACATAAGCAGTGTCTTTGTGGA
GAGGTATTAAGAGGAGTAAAAAAGCCAACTGATTGCAAATTGTTTGCTAAGGCTTGCCTGCCAGAAAATCCTTTAGGATC
CTGTATGGTTTCATCAGAAGGAGCTTGCGCTGCTGTTTATGCTTATGGACGGGTGAATGCTTTATGA

Upstream 100 bases:

>100_bases
ACGTCATTATTCATGCAGGATTCGCCTTAACAAAACTGGATGAAAGAGAGGCAAACAAAACATTGAGTTTGTTTGCCCAT
ATGCTAAAGGATGGCTTGAA

Downstream 100 bases:

>100_bases
GTGAAATCCTGATAACTAAAAACTTAACTGGGCCAAAACTGAGTTTTAAAGAAGGTACTATCAATTTGACCCATGGCAGT
GGTGGCCGTGCTATGGCTCA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKYIEEFRNGVYAQAIVNEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPVARIDKAIAL
ASMPQVILCSYADMLRVPGTGQRSLLTAKAGGADVRMIYSADDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSYPYEHVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCEVEIQYTRAVNRTGNLLSQHIMAEILEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPDSAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Sequences:

>Translated_368_residues
MKYIEEFRNGVYAQAIVNEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPVARIDKAIAL
ASMPQVILCSYADMLRVPGTGQRSLLTAKAGGADVRMIYSADDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSYPYEHVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCEVEIQYTRAVNRTGNLLSQHIMAEILEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPDSAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL
>Mature_368_residues
MKYIEEFRNGVYAQAIVNEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPVARIDKAIAL
ASMPQVILCSYADMLRVPGTGQRSLLTAKAGGADVRMIYSADDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSYPYEHVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCEVEIQYTRAVNRTGNLLSQHIMAEILEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPDSAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=46.0490463215259, Blast_Score=348, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40580; Mature: 40580

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIEEFRNGVYAQAIVNEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPVARIDKAIALASMPQVILCSYADMLRVPGTGQRSLLTAKAGGADVRMIYS
CCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
ADDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSYPYEHVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCEVEIQYTRAVNRTGNLLSQHIMAEILEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPDSAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC
>Mature Secondary Structure
MKYIEEFRNGVYAQAIVNEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPVARIDKAIALASMPQVILCSYADMLRVPGTGQRSLLTAKAGGADVRMIYS
CCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
ADDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSYPYEHVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCEVEIQYTRAVNRTGNLLSQHIMAEILEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPDSAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488 [H]