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The map label for this gene is hypE [H]

Identifier: 54295306

GI number: 54295306

Start: 2721705

End: 2722763

Strand: Reverse

Name: hypE [H]

Synonym: lpl2391

Alternate gene names: 54295306

Gene position: 2722763-2721705 (Counterclockwise)

Preceding gene: 54295307

Following gene: 54295305

Centisome position: 81.38

GC content: 44.1

Gene sequence:

>1059_bases
ATGAGTGAAATCCTGATAACTAAAAACTTAACTGGGCCAAAACTGAGTTTTAAAGAAGGTACTATCAATTTGACCCATGG
CAGTGGTGGCCGTGCTATGGCTCAGCTAATCGAACAATTATTTTTAACTGCGTTTGATAACGAGTGGTTGGCACAGAAAA
ATGATCAGGCTTGCTTTATTGTTCCTTCAGGGCGTATGGTCATGGCAACCGATGCTCATGTTATTTCCCCACTTTTTTTT
CCTGGCGGCGACATTGGTTCTTTGTCAGTGCATGGAACGGTTAATGATGTGGCTATGTCAGGGGCAAAACCTTTGTATTT
GACAGCCAGCTTTATTCTTGAGGAAGGGTTTCCTCTTAACGATTTGAGAAAAATCGTTTATTCGATGGCTGATGCAGCCA
GGCAAGCAGCTGTTGCTATCATTGCTGGCGATACAAAAGTTGTGGAGCGGGGAAAAGGCGATGGCATTTTTATTACAACA
ACCGGAGTAGGTATTGTCCCTGAGGGAATTCATATTTCAGGTGACGCAGCAAAACCTGGTGACAAAATCATTGTGAGTGG
TTTTCTAGGGGATCATGGGGTAGCTATTATGGCGCATCGCAATAACCTGGAATTTCAGACCAGAGTGCAGTCTGATACAG
CTTCCTTGCATGAGCTTGTCGGTGAGATGGTGAAAGCGGTTCCAGATCTTCATTGCTTGCGTGATCCTACGCGTGGCGGG
CTCGCAACGACACTGAATGAATTGGCCTTACAATCCAAAGTCGGGTTTGTTATTGATGAAAGTAAAATTCCGATTCGTAC
CGAGGTTGCTAGCGCGTGCGAATTATTAGGTCTTGATCCTCTTTATGTTGCTAATGAAGGGAAATTAATTGCGATTTGTC
CTTCTGAAAAGGCAGAGAGGCTATTAATTGCTATGAAAGCGCACCCCTTAGGTTTACATGCTGAAATCATTGGCGAAGTG
ATTGAAGATCATCGCTGTTTTGTTCAGCTGAAAACAAAATTGGGCGGGTTACGAATTGTGGATTGGCTGGCCGGAGAGCA
ATTACCCAGAATCTGTTAA

Upstream 100 bases:

>100_bases
TTGCTAAGGCTTGCCTGCCAGAAAATCCTTTAGGATCCTGTATGGTTTCATCAGAAGGAGCTTGCGCTGCTGTTTATGCT
TATGGACGGGTGAATGCTTT

Downstream 100 bases:

>100_bases
TTAAGTACTAATGGTTGACAAGAAAGGATGACGAGGATGAATGACAAGACGGCCAGTTTTTTGCCTCATGATAAATTGCA
ACATTTAATTGATTCTTTGC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSEILITKNLTGPKLSFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFF
PGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLNDLRKIVYSMADAARQAAVAIIAGDTKVVERGKGDGIFITT
TGVGIVPEGIHISGDAAKPGDKIIVSGFLGDHGVAIMAHRNNLEFQTRVQSDTASLHELVGEMVKAVPDLHCLRDPTRGG
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAICPSEKAERLLIAMKAHPLGLHAEIIGEV
IEDHRCFVQLKTKLGGLRIVDWLAGEQLPRIC

Sequences:

>Translated_352_residues
MSEILITKNLTGPKLSFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFF
PGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLNDLRKIVYSMADAARQAAVAIIAGDTKVVERGKGDGIFITT
TGVGIVPEGIHISGDAAKPGDKIIVSGFLGDHGVAIMAHRNNLEFQTRVQSDTASLHELVGEMVKAVPDLHCLRDPTRGG
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAICPSEKAERLLIAMKAHPLGLHAEIIGEV
IEDHRCFVQLKTKLGGLRIVDWLAGEQLPRIC
>Mature_351_residues
SEILITKNLTGPKLSFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFFP
GGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLNDLRKIVYSMADAARQAAVAIIAGDTKVVERGKGDGIFITTT
GVGIVPEGIHISGDAAKPGDKIIVSGFLGDHGVAIMAHRNNLEFQTRVQSDTASLHELVGEMVKAVPDLHCLRDPTRGGL
ATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAICPSEKAERLLIAMKAHPLGLHAEIIGEVI
EDHRCFVQLKTKLGGLRIVDWLAGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=46.2908011869436, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 37690; Mature: 37559

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEILITKNLTGPKLSFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFI
CCCEEEEECCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
VPSGRMVMATDAHVISPLFFPGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLN
EECCCEEEEECCHHHCEEECCCCCCCCEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCHH
DLRKIVYSMADAARQAAVAIIAGDTKVVERGKGDGIFITTTGVGIVPEGIHISGDAAKPG
HHHHHHHHHHHHHHHEEEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCEEECCCCCCCC
DKIIVSGFLGDHGVAIMAHRNNLEFQTRVQSDTASLHELVGEMVKAVPDLHCLRDPTRGG
CEEEEEEEECCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAICPSEKAER
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCE
LLIAMKAHPLGLHAEIIGEVIEDHRCFVQLKTKLGGLRIVDWLAGEQLPRIC
EEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure 
SEILITKNLTGPKLSFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFI
CCEEEEECCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
VPSGRMVMATDAHVISPLFFPGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLN
EECCCEEEEECCHHHCEEECCCCCCCCEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCHH
DLRKIVYSMADAARQAAVAIIAGDTKVVERGKGDGIFITTTGVGIVPEGIHISGDAAKPG
HHHHHHHHHHHHHHHEEEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCEEECCCCCCCC
DKIIVSGFLGDHGVAIMAHRNNLEFQTRVQSDTASLHELVGEMVKAVPDLHCLRDPTRGG
CEEEEEEEECCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAICPSEKAER
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCE
LLIAMKAHPLGLHAEIIGEVIEDHRCFVQLKTKLGGLRIVDWLAGEQLPRIC
EEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]