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The map label for this gene is gcp [H]

Identifier: 54295199

GI number: 54295199

Start: 2597755

End: 2598756

Strand: Reverse

Name: gcp [H]

Synonym: lpl2279

Alternate gene names: 54295199

Gene position: 2598756-2597755 (Counterclockwise)

Preceding gene: 54295204

Following gene: 54295197

Centisome position: 77.67

GC content: 44.81

Gene sequence:

>1002_bases
ATGCTTGTATTGGGTATAGAGTCTTCCTGTGATGAAACAGGTGTTGCTGTCTATGATTCAGAATCAGGATTATTGTCCCA
CGCCTTGCATTCACAAATTGCCACTCACCGTGTACATGGCGGTGTTGTTCCAGAACTGGCATCAAGAGATCATGTGAATT
ACTTGGTTCCTTTGGTCGATGAGGTATTAACTAAAGCGAAAATTCGTAAAAACCAATTGGATGGAATAGCCTACACCGCA
GGACCTGGATTAATTGGCGCTTTGTTAGTTGGCTCCTGCTTTGCCAAAAGTCTCGCCTACGCCTTAAATATCCCGGCATT
GGCAATTCATCATTTGGAAGCCCATCTGTTAGCCGCAAAAATGGAAACCCCATCCCTGGATTTTCCCTTTATTGCCCTGT
TGGTTTCCGGTGGCCATTGTCAATTGATAGAAGTAAATAATATCGGTGAGTATCGATTATTAGGAGACACTCTCGACGAT
GCAGTAGGAGAAGCTTTTGACAAGACAGCCAAACTGATGGGGATTCCCTATCCTGGAGGAGCCGTGTTGGCAAATTTGGC
TGATCAATGTTTATCAACTCCCTATCAATTTCCCCGTCCCATGACTGACAGGCCAGGCTTGGACTTTAGTTTTAGCGGAC
TAAAAACTCATGCCTTAAATACCTGGAATCAAAGTGCAAAAAAGCAAGGCGACCGCTCCGAAATTGCAAAAGCATTTCAA
CAAGCAGTAGTTGAAACACTAATTATAAAATGCAAAAGAGCAATTAAAGAATCTCAATCAAAGCGCTTAGTGGTAGCCGG
TGGAGTAGGAGCCAATAAAGCGTTGCGTAGCGCTTTGCAAAAATGGATTAATGACATCAAAGGGGAAGTATACTTCCCCG
CTCTGGAATATTGCACAGATAATGGTGCAATGGTCGCTTATGCAGGATGTTTGCGCATGATGCGGGGGGAGAGTGATGGG
GGGTTGGGAGTTATGGTCAAACCTCGTTGGCCCCTCGCTTGA

Upstream 100 bases:

>100_bases
ATCAAGGCATTGTTCTTTAATTTAATGGTATCTTTTGTCTGTGATATAATTGAAAAATGATTAAAATCTGGAAAATTGAT
TCCGATTATTGAGGTAGTTC

Downstream 100 bases:

>100_bases
ACGCCCGTCTTCGGCGCATCTTGCCAGATCATTGCTCTAAAAAATGCTCGTGTACTCATCTGTACACTCCGCTTTTTTAG
TCGCAACGATCTGTCAACCT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVDEVLTKAKIRKNQLDGIAYTA
GPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAKMETPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDD
AVGEAFDKTAKLMGIPYPGGAVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQ
QAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTDNGAMVAYAGCLRMMRGESDG
GLGVMVKPRWPLA

Sequences:

>Translated_333_residues
MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVDEVLTKAKIRKNQLDGIAYTA
GPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAKMETPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDD
AVGEAFDKTAKLMGIPYPGGAVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQ
QAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTDNGAMVAYAGCLRMMRGESDG
GLGVMVKPRWPLA
>Mature_333_residues
MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVDEVLTKAKIRKNQLDGIAYTA
GPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAKMETPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDD
AVGEAFDKTAKLMGIPYPGGAVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQ
QAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTDNGAMVAYAGCLRMMRGESDG
GLGVMVKPRWPLA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=361, Percent_Identity=32.6869806094183, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI8923380, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=57.0570570570571, Blast_Score=403, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=29.2168674698795, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=30.8868501529052, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=365, Percent_Identity=30.958904109589, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=26.2857142857143, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=33.8192419825073, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21357207, Length=324, Percent_Identity=28.3950617283951, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35754; Mature: 35754

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVD
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHH
EVLTKAKIRKNQLDGIAYTAGPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAK
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
METPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDDAVGEAFDKTAKLMGIPYPGG
CCCCCCCCCHHHHEECCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCH
AVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
QAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHCC
NGAMVAYAGCLRMMRGESDGGLGVMVKPRWPLA
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVD
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHH
EVLTKAKIRKNQLDGIAYTAGPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAK
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
METPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDDAVGEAFDKTAKLMGIPYPGG
CCCCCCCCCHHHHEECCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCH
AVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
QAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHCC
NGAMVAYAGCLRMMRGESDGGLGVMVKPRWPLA
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA