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The map label for this gene is gatA1 [H]

Identifier: 54295197

GI number: 54295197

Start: 2594734

End: 2596143

Strand: Reverse

Name: gatA1 [H]

Synonym: lpl2277

Alternate gene names: 54295197

Gene position: 2596143-2594734 (Counterclockwise)

Preceding gene: 54295199

Following gene: 54295195

Centisome position: 77.6

GC content: 44.68

Gene sequence:

>1410_bases
ATGGATGCCATTCATCTCCTTTCTGCAACAGAAATCATTCGCCGCATTAAAATGAAAGAACTCTCGGCTGCAGAGGTCAT
GGTGGCGCACTTAAACCATATTGATAAGATTAATCCTGTAATCAATGCGCTCACCGAACGTATTCCCCCTGAGGAATGCT
TAAAGCGGGCAAAGGAAATTGACAAGAGTATCGCTTCGAAAAAAAATCTGAACAAGTTAATGGGGTTGCCTGTTGCCATA
AAAGACGCTTTGTATGTGAAAGGACTAATTTGTTCTTCGGCATGTTCAGGATTTTACAAGGGAGAAAAAGCAGTACGTGA
TGCGACCCTGGTTTCTCGACTGAAAAAGGAAGGAGCAATTATTCTTGGCTTAACTAATGTTCCTGAATTGTGTCGCGGTG
GTGATTCGGATAATTTAATCTATGGACGGACCAATAATCCTTATGATCTGGCAAGAACCAGTGGAGGCAGTAGTGGTGGT
TCCGCGGCTTTGATCGCTGCAGGAGGCGTTCCTTTTGCTTTGGGTTCCGATGGTGGAGGTAGTTTAATGCAGCCTGCCCA
TTGTTGCGGTATTGTTGCATTGAAGCCAACACATGGCCGTCTTCCTCATACAGGATCTGTAGGTGGGGATTCCTATGGTC
TTATTGGCAACCTGATTTCTTTTGGACCAATGGCTCGTTCTGTCAGTGACCTTCGTTTAGGACTCTCCGTGCTTGCGGGT
TCTGACCAATATGATCCTTATACAAATCCGGTTCCTGTTATGCCTGCTGCACCACTAAAAAAATTACGTGTAGCCTATTT
TACAGAGAATGGTTTTACGCCAGTTGATGCAGAGATACAGAACGTTGTTAAATCAGCAGCCTTGGCTTTGCAGGATGATG
TGGCTATAGTGAGGGAGGTACGACCTGATTGTGTCAGCAAGGCTTTTGAATTGCACTGGGAGCTTTTTCTCGGGGGCGAT
CGCGGAGCTGGATTTAAAACTATGTTATCGGAGTTAGGGGTTAACAATCTGTCATGGGAGTTACGAGAGTTCTTGCGTCA
AGCAGAACAAACTCAATTCTCGGTGACTCAATTGCATCAACGTATGCGTGAAATCGATTTGTTTCGTCTGGAATTCGCTT
TATTCATGCAAGACTATGATGTATTGATTAGTCCAGTGTTTCCAACAGTAGCAAAACCGCATGGGATTGGGATTAGAGAA
ATCAGCGATTTTTCCTATGCGATGACACACAATTTAAGTGGATTTCCAACGATCAGCCTAAGATGCGGGACTTCAGCCGA
GGGGTTGTCCATTAATGTATTAATAGCCGCTAATCGCTGGAAAGATACTACCTCTCTGGCTGTTGCAGAACGCGTTGAGC
AATTAATGGGGGGATATAACCCCCCTTCTCTAATCCACTCTCTGCAATAA

Upstream 100 bases:

>100_bases
TTTGCAATAGTTTGAGACGGATACTGAATGTTGCGTTTTAGTCCTGTTCGGTGTGTCACTATTATTCTACTCCATTATTT
AAGGAAATTTTACTAAAGCT

Downstream 100 bases:

>100_bases
AGCAAGAATCAATAATTTTTGAAACAGTGAACTAGGGCAGAAACAAGGCTTGCAAATCATTAGTATATTGCCTGCCTAAT
GGTGTTACTTGCCAATGAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Glu-ADT subunit A 1 [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MDAIHLLSATEIIRRIKMKELSAAEVMVAHLNHIDKINPVINALTERIPPEECLKRAKEIDKSIASKKNLNKLMGLPVAI
KDALYVKGLICSSACSGFYKGEKAVRDATLVSRLKKEGAIILGLTNVPELCRGGDSDNLIYGRTNNPYDLARTSGGSSGG
SAALIAAGGVPFALGSDGGGSLMQPAHCCGIVALKPTHGRLPHTGSVGGDSYGLIGNLISFGPMARSVSDLRLGLSVLAG
SDQYDPYTNPVPVMPAAPLKKLRVAYFTENGFTPVDAEIQNVVKSAALALQDDVAIVREVRPDCVSKAFELHWELFLGGD
RGAGFKTMLSELGVNNLSWELREFLRQAEQTQFSVTQLHQRMREIDLFRLEFALFMQDYDVLISPVFPTVAKPHGIGIRE
ISDFSYAMTHNLSGFPTISLRCGTSAEGLSINVLIAANRWKDTTSLAVAERVEQLMGGYNPPSLIHSLQ

Sequences:

>Translated_469_residues
MDAIHLLSATEIIRRIKMKELSAAEVMVAHLNHIDKINPVINALTERIPPEECLKRAKEIDKSIASKKNLNKLMGLPVAI
KDALYVKGLICSSACSGFYKGEKAVRDATLVSRLKKEGAIILGLTNVPELCRGGDSDNLIYGRTNNPYDLARTSGGSSGG
SAALIAAGGVPFALGSDGGGSLMQPAHCCGIVALKPTHGRLPHTGSVGGDSYGLIGNLISFGPMARSVSDLRLGLSVLAG
SDQYDPYTNPVPVMPAAPLKKLRVAYFTENGFTPVDAEIQNVVKSAALALQDDVAIVREVRPDCVSKAFELHWELFLGGD
RGAGFKTMLSELGVNNLSWELREFLRQAEQTQFSVTQLHQRMREIDLFRLEFALFMQDYDVLISPVFPTVAKPHGIGIRE
ISDFSYAMTHNLSGFPTISLRCGTSAEGLSINVLIAANRWKDTTSLAVAERVEQLMGGYNPPSLIHSLQ
>Mature_469_residues
MDAIHLLSATEIIRRIKMKELSAAEVMVAHLNHIDKINPVINALTERIPPEECLKRAKEIDKSIASKKNLNKLMGLPVAI
KDALYVKGLICSSACSGFYKGEKAVRDATLVSRLKKEGAIILGLTNVPELCRGGDSDNLIYGRTNNPYDLARTSGGSSGG
SAALIAAGGVPFALGSDGGGSLMQPAHCCGIVALKPTHGRLPHTGSVGGDSYGLIGNLISFGPMARSVSDLRLGLSVLAG
SDQYDPYTNPVPVMPAAPLKKLRVAYFTENGFTPVDAEIQNVVKSAALALQDDVAIVREVRPDCVSKAFELHWELFLGGD
RGAGFKTMLSELGVNNLSWELREFLRQAEQTQFSVTQLHQRMREIDLFRLEFALFMQDYDVLISPVFPTVAKPHGIGIRE
ISDFSYAMTHNLSGFPTISLRCGTSAEGLSINVLIAANRWKDTTSLAVAERVEQLMGGYNPPSLIHSLQ

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=494, Percent_Identity=29.5546558704453, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI222831590, Length=508, Percent_Identity=24.2125984251968, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI166795287, Length=438, Percent_Identity=28.0821917808219, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537465, Length=501, Percent_Identity=29.7405189620758, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17556264, Length=306, Percent_Identity=32.0261437908497, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17538252, Length=484, Percent_Identity=28.3057851239669, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17556276, Length=313, Percent_Identity=33.5463258785943, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17556278, Length=313, Percent_Identity=33.5463258785943, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990152, Length=480, Percent_Identity=26.0416666666667, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17538254, Length=383, Percent_Identity=30.5483028720627, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32565337, Length=413, Percent_Identity=24.455205811138, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543272, Length=450, Percent_Identity=23.5555555555556, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320448, Length=242, Percent_Identity=34.7107438016529, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319685, Length=227, Percent_Identity=33.920704845815, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323950, Length=188, Percent_Identity=34.0425531914894, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652985, Length=497, Percent_Identity=29.7786720321932, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19922090, Length=497, Percent_Identity=29.7786720321932, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24652981, Length=497, Percent_Identity=29.7786720321932, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24652983, Length=497, Percent_Identity=29.7786720321932, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI45550774, Length=491, Percent_Identity=28.1059063136456, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24648435, Length=491, Percent_Identity=28.1059063136456, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24648437, Length=491, Percent_Identity=28.1059063136456, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356731, Length=480, Percent_Identity=29.375, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161078093, Length=486, Percent_Identity=29.2181069958848, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24644968, Length=496, Percent_Identity=26.4112903225806, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24648441, Length=423, Percent_Identity=27.4231678486998, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24648439, Length=423, Percent_Identity=27.4231678486998, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24648113, Length=284, Percent_Identity=32.7464788732394, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 50674; Mature: 50674

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIHLLSATEIIRRIKMKELSAAEVMVAHLNHIDKINPVINALTERIPPEECLKRAKEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DKSIASKKNLNKLMGLPVAIKDALYVKGLICSSACSGFYKGEKAVRDATLVSRLKKEGAI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCE
ILGLTNVPELCRGGDSDNLIYGRTNNPYDLARTSGGSSGGSAALIAAGGVPFALGSDGGG
EEEECCCHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCCCCEEEEEECCCCEEECCCCCC
SLMQPAHCCGIVALKPTHGRLPHTGSVGGDSYGLIGNLISFGPMARSVSDLRLGLSVLAG
CCCCCHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDQYDPYTNPVPVMPAAPLKKLRVAYFTENGFTPVDAEIQNVVKSAALALQDDVAIVREV
CCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
RPDCVSKAFELHWELFLGGDRGAGFKTMLSELGVNNLSWELREFLRQAEQTQFSVTQLHQ
CHHHHHHHHHEEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RMREIDLFRLEFALFMQDYDVLISPVFPTVAKPHGIGIREISDFSYAMTHNLSGFPTISL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCHHHHHHCCCCCCCEEEE
RCGTSAEGLSINVLIAANRWKDTTSLAVAERVEQLMGGYNPPSLIHSLQ
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MDAIHLLSATEIIRRIKMKELSAAEVMVAHLNHIDKINPVINALTERIPPEECLKRAKEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DKSIASKKNLNKLMGLPVAIKDALYVKGLICSSACSGFYKGEKAVRDATLVSRLKKEGAI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCE
ILGLTNVPELCRGGDSDNLIYGRTNNPYDLARTSGGSSGGSAALIAAGGVPFALGSDGGG
EEEECCCHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCCCCEEEEEECCCCEEECCCCCC
SLMQPAHCCGIVALKPTHGRLPHTGSVGGDSYGLIGNLISFGPMARSVSDLRLGLSVLAG
CCCCCHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDQYDPYTNPVPVMPAAPLKKLRVAYFTENGFTPVDAEIQNVVKSAALALQDDVAIVREV
CCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
RPDCVSKAFELHWELFLGGDRGAGFKTMLSELGVNNLSWELREFLRQAEQTQFSVTQLHQ
CHHHHHHHHHEEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RMREIDLFRLEFALFMQDYDVLISPVFPTVAKPHGIGIREISDFSYAMTHNLSGFPTISL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCHHHHHHCCCCCCCEEEE
RCGTSAEGLSINVLIAANRWKDTTSLAVAERVEQLMGGYNPPSLIHSLQ
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]