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The map label for this gene is yqjD [H]

Identifier: 54295072

GI number: 54295072

Start: 2459237

End: 2460658

Strand: Reverse

Name: yqjD [H]

Synonym: lpl2152

Alternate gene names: 54295072

Gene position: 2460658-2459237 (Counterclockwise)

Preceding gene: 54295079

Following gene: 54295071

Centisome position: 73.55

GC content: 41.98

Gene sequence:

>1422_bases
ATGTCTTCCCAACATACAGATAAGACGTTAATAAAATGGATAGATAATTTAATTGATGAACAAAGCTTTTTACCAATAGG
ATCTGAATATATTCCAGATAATAAACCTCATTCCCTTCCTGGCGCTGAGGTGATTACCGGATTAGCCAAAGTGAATCAAA
GGCCAGTAGCGATTTATGCTCATGATTCTTCAGTCAACAGGGGGTATGTTACCCGACAAGGCGCTAGAAAGATTATTCAT
TTAATGGATAAAGCGGAAAAATTACGCATTCCTATCGTTGCCTTTTTAGCATCTCCAGGGGTTTCTCTCGAAGAAAATTT
GCTGAGTGGCGACGAATACACTCAAATTATTGCTCGAAATATTAGGCTGTCAGGAATTATCCCACAATTTGCAGTGATAC
TGGCACCCACTCTTGGAGCGCCGGCATATTCCGCTGTGTTAATGGACTTATTATTTTTTAACAAGCATAGAAGCTATCTT
ATGGTGACTAGCCCTACGGTAGTACAACAAGCCATTGGTGAAAAAGTGACTATGGGCGAGCTGGGGAGCGCAACACTGCA
TGCAACGACAACGGGTATTGCTGATTTCGTGGACGATAGTGTTACCGCACAAATAAACCATGTGAAAGCAATACTTGGTT
TTTTTCCTCTACATACCAATGAACGCCCGCCTGTTCATCCTATCATGGAGCCTAATCACCCCATTCCTGATATTCCTGCA
AATCCGAGAATGCCATTTAATATGCTCAATTTAATTCAGGCTGTCGTGGATAATTCAAACGTTATCCAGTACAAAAGGAC
TTATGGACAGGCGATGATTTGCGCTTTTGTGCATATACACGGCTTTGCTGTTGGGGTTGTCGCTAATCAAAGCATTCGTT
ACAGCGGAGCCATCGATTCCGATGCGGCTCAAAAAGCAGCCAAATTTATAAGAATATGTGATGCTTATTCTATACCGATT
TTGACTTTTATCGATGTTCCCGGTTTTATGCCCGGTAAAAGAGAGGAGCAAAAGGGATTATTGCAGCATGGTGCAAGGTT
TTGCGTCGCTATGCAAACCAGAGTGCCAAGGCTAAGTGTCATCGTGCGTAAATGTTATGGAGCGGCAGCTTTTCTCATGA
TGCAAACCAAATCACAGAATGGAGATTTGGTTTTGGCTCTGGAAACAGCAAATCTTGGTGTCATGGGAAAGGAAACAACT
AATAAGGTGCAAGCCATGGATGGTCAACCAGTAAAGGAATCATCACAATCCCAATTGACAGAAAAGTCTCAAATTGATGA
TTCCCTCATGGAAGCTTATTCATTGGGCTTGATTGATGAAATTATCCAGGCAGCGCAAATTCGCAGTCGCCTTGCCTCTC
ATTTGGAGTTTTTATATAGAAGAATGGAAACCATGCCCCCGGCAAAACACTCTATTGTATAA

Upstream 100 bases:

>100_bases
GTAGCCTATTTTGGGAATTAAGTTATTATGAGTATTGATAAAATTTCCAAGTTACAAAGTCTCAGATTCCAAGATTTAAA
TATTGCAAGAGGAAAGAAGT

Downstream 100 bases:

>100_bases
GGAAAATAATGACCTCTTATGAAAATTTGATACAACTGTCTGAATTTTTTGAGTCATGCCTGGGTAATCCTCTGGAAGAC
AATTCCCCTGTTAATTTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSSQHTDKTLIKWIDNLIDEQSFLPIGSEYIPDNKPHSLPGAEVITGLAKVNQRPVAIYAHDSSVNRGYVTRQGARKIIH
LMDKAEKLRIPIVAFLASPGVSLEENLLSGDEYTQIIARNIRLSGIIPQFAVILAPTLGAPAYSAVLMDLLFFNKHRSYL
MVTSPTVVQQAIGEKVTMGELGSATLHATTTGIADFVDDSVTAQINHVKAILGFFPLHTNERPPVHPIMEPNHPIPDIPA
NPRMPFNMLNLIQAVVDNSNVIQYKRTYGQAMICAFVHIHGFAVGVVANQSIRYSGAIDSDAAQKAAKFIRICDAYSIPI
LTFIDVPGFMPGKREEQKGLLQHGARFCVAMQTRVPRLSVIVRKCYGAAAFLMMQTKSQNGDLVLALETANLGVMGKETT
NKVQAMDGQPVKESSQSQLTEKSQIDDSLMEAYSLGLIDEIIQAAQIRSRLASHLEFLYRRMETMPPAKHSIV

Sequences:

>Translated_473_residues
MSSQHTDKTLIKWIDNLIDEQSFLPIGSEYIPDNKPHSLPGAEVITGLAKVNQRPVAIYAHDSSVNRGYVTRQGARKIIH
LMDKAEKLRIPIVAFLASPGVSLEENLLSGDEYTQIIARNIRLSGIIPQFAVILAPTLGAPAYSAVLMDLLFFNKHRSYL
MVTSPTVVQQAIGEKVTMGELGSATLHATTTGIADFVDDSVTAQINHVKAILGFFPLHTNERPPVHPIMEPNHPIPDIPA
NPRMPFNMLNLIQAVVDNSNVIQYKRTYGQAMICAFVHIHGFAVGVVANQSIRYSGAIDSDAAQKAAKFIRICDAYSIPI
LTFIDVPGFMPGKREEQKGLLQHGARFCVAMQTRVPRLSVIVRKCYGAAAFLMMQTKSQNGDLVLALETANLGVMGKETT
NKVQAMDGQPVKESSQSQLTEKSQIDDSLMEAYSLGLIDEIIQAAQIRSRLASHLEFLYRRMETMPPAKHSIV
>Mature_472_residues
SSQHTDKTLIKWIDNLIDEQSFLPIGSEYIPDNKPHSLPGAEVITGLAKVNQRPVAIYAHDSSVNRGYVTRQGARKIIHL
MDKAEKLRIPIVAFLASPGVSLEENLLSGDEYTQIIARNIRLSGIIPQFAVILAPTLGAPAYSAVLMDLLFFNKHRSYLM
VTSPTVVQQAIGEKVTMGELGSATLHATTTGIADFVDDSVTAQINHVKAILGFFPLHTNERPPVHPIMEPNHPIPDIPAN
PRMPFNMLNLIQAVVDNSNVIQYKRTYGQAMICAFVHIHGFAVGVVANQSIRYSGAIDSDAAQKAAKFIRICDAYSIPIL
TFIDVPGFMPGKREEQKGLLQHGARFCVAMQTRVPRLSVIVRKCYGAAAFLMMQTKSQNGDLVLALETANLGVMGKETTN
KVQAMDGQPVKESSQSQLTEKSQIDDSLMEAYSLGLIDEIIQAAQIRSRLASHLEFLYRRMETMPPAKHSIV

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=441, Percent_Identity=32.6530612244898, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI295821216, Length=461, Percent_Identity=31.4533622559653, Blast_Score=252, Evalue=7e-67,
Organism=Homo sapiens, GI11545863, Length=446, Percent_Identity=25.5605381165919, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25147362, Length=484, Percent_Identity=28.7190082644628, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI25147359, Length=484, Percent_Identity=28.7190082644628, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17552936, Length=404, Percent_Identity=24.7524752475248, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24586065, Length=417, Percent_Identity=23.7410071942446, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 52036; Mature: 51905

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQHTDKTLIKWIDNLIDEQSFLPIGSEYIPDNKPHSLPGAEVITGLAKVNQRPVAIYA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
HDSSVNRGYVTRQGARKIIHLMDKAEKLRIPIVAFLASPGVSLEENLLSGDEYTQIIARN
ECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHH
IRLSGIIPQFAVILAPTLGAPAYSAVLMDLLFFNKHRSYLMVTSPTVVQQAIGEKVTMGE
CHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCEECCC
LGSATLHATTTGIADFVDDSVTAQINHVKAILGFFPLHTNERPPVHPIMEPNHPIPDIPA
CCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
NPRMPFNMLNLIQAVVDNSNVIQYKRTYGQAMICAFVHIHGFAVGVVANQSIRYSGAIDS
CCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCH
DAAQKAAKFIRICDAYSIPILTFIDVPGFMPGKREEQKGLLQHGARFCVAMQTRVPRLSV
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEHHHHCCCHHHH
IVRKCYGAAAFLMMQTKSQNGDLVLALETANLGVMGKETTNKVQAMDGQPVKESSQSQLT
HHHHHHHHHEEEHEEECCCCCCEEEEEEECCCCEECCCCCCHHCCCCCCCCCCCHHHHHH
EKSQIDDSLMEAYSLGLIDEIIQAAQIRSRLASHLEFLYRRMETMPPAKHSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSQHTDKTLIKWIDNLIDEQSFLPIGSEYIPDNKPHSLPGAEVITGLAKVNQRPVAIYA
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
HDSSVNRGYVTRQGARKIIHLMDKAEKLRIPIVAFLASPGVSLEENLLSGDEYTQIIARN
ECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHH
IRLSGIIPQFAVILAPTLGAPAYSAVLMDLLFFNKHRSYLMVTSPTVVQQAIGEKVTMGE
CHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCEECCC
LGSATLHATTTGIADFVDDSVTAQINHVKAILGFFPLHTNERPPVHPIMEPNHPIPDIPA
CCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
NPRMPFNMLNLIQAVVDNSNVIQYKRTYGQAMICAFVHIHGFAVGVVANQSIRYSGAIDS
CCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCH
DAAQKAAKFIRICDAYSIPILTFIDVPGFMPGKREEQKGLLQHGARFCVAMQTRVPRLSV
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEHHHHCCCHHHH
IVRKCYGAAAFLMMQTKSQNGDLVLALETANLGVMGKETTNKVQAMDGQPVKESSQSQLT
HHHHHHHHHEEEHEEECCCCCCEEEEEEECCCCEECCCCCCHHCCCCCCCCCCCHHHHHH
EKSQIDDSLMEAYSLGLIDEIIQAAQIRSRLASHLEFLYRRMETMPPAKHSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]