Click here to switch to the map view.

The map label for this gene is gst [H]

Identifier: 54294795

GI number: 54294795

Start: 2095217

End: 2095822

Strand: Reverse

Name: gst [H]

Synonym: lpl1872

Alternate gene names: 54294795

Gene position: 2095822-2095217 (Counterclockwise)

Preceding gene: 54294796

Following gene: 54294794

Centisome position: 62.64

GC content: 37.13

Gene sequence:

>606_bases
ATGAAATTATATTATTGCAGAGGTGCTTGTTCATTAGTAGTTCGTATTATACTCAATGAGTTAGGGTTAAACTTCCAGGA
TGAAGAGGTCGATTTAAAAGTCAAAAAAACAGCAGGTGGCGAGGATTTTTTTAAAATTAATCCTAAAGGAGCGGTCCCAA
CCCTGGTTCTTGATAACGGCGATGTCCTGACTGAAAATCAGGTTATTCTACAGTATCTGGCAGATACTACTCCAGGACAG
AAATTGTTGGCTGCTGTTGGAGAGAGTAAAAGATATCATACTCTGGAATGGTTAAATTATATTTCTACAGAGCTTCATAA
GTCGCTTGGTATGTTTTTTAATCCTACTGTTTCAGAGGAAATAAAATCCAAAATTTTGACACCTTTAGTCATGACCCGTT
TTGCTTATACCAATACTCGTTTGGCAAAAGGATCTTGTTTGATGGGGAGTGAATTTAGTTTACCTGATGCCTATCTGTTT
GTTATGGTAAGCTGGGCAAAATATTTCAAACTGGATTTGTCTCAGTTTGAGCATTTGACAAAATTTATGGATCTTATGCT
GGCTCGCCCTTCAGTTGCCAAGTCACTACAGCAAGAAAAATTATAG

Upstream 100 bases:

>100_bases
ATCATCCTTTTTCACTGTATGGTTTTTTACATTTCAAGTTTTTTGCTGCATTTTATGCTAACTTAGCTATTATTATTTAA
ACATCATCAAAGGAGTGAAC

Downstream 100 bases:

>100_bases
CGCGGGTTGTGTTATTAATTCATTGCAACCCAATTTGCTTCTTCTATATAGTATTTTTTAAAAGGAGGAGTAAGAGTCAT
TATATCCAATGCTTTGAAGT

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLYYCRGACSLVVRIILNELGLNFQDEEVDLKVKKTAGGEDFFKINPKGAVPTLVLDNGDVLTENQVILQYLADTTPGQ
KLLAAVGESKRYHTLEWLNYISTELHKSLGMFFNPTVSEEIKSKILTPLVMTRFAYTNTRLAKGSCLMGSEFSLPDAYLF
VMVSWAKYFKLDLSQFEHLTKFMDLMLARPSVAKSLQQEKL

Sequences:

>Translated_201_residues
MKLYYCRGACSLVVRIILNELGLNFQDEEVDLKVKKTAGGEDFFKINPKGAVPTLVLDNGDVLTENQVILQYLADTTPGQ
KLLAAVGESKRYHTLEWLNYISTELHKSLGMFFNPTVSEEIKSKILTPLVMTRFAYTNTRLAKGSCLMGSEFSLPDAYLF
VMVSWAKYFKLDLSQFEHLTKFMDLMLARPSVAKSLQQEKL
>Mature_201_residues
MKLYYCRGACSLVVRIILNELGLNFQDEEVDLKVKKTAGGEDFFKINPKGAVPTLVLDNGDVLTENQVILQYLADTTPGQ
KLLAAVGESKRYHTLEWLNYISTELHKSLGMFFNPTVSEEIKSKILTPLVMTRFAYTNTRLAKGSCLMGSEFSLPDAYLF
VMVSWAKYFKLDLSQFEHLTKFMDLMLARPSVAKSLQQEKL

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=45.273631840796, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22776; Mature: 22776

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYCRGACSLVVRIILNELGLNFQDEEVDLKVKKTAGGEDFFKINPKGAVPTLVLDNG
CEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEECCC
DVLTENQVILQYLADTTPGQKLLAAVGESKRYHTLEWLNYISTELHKSLGMFFNPTVSEE
CEEECHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IKSKILTPLVMTRFAYTNTRLAKGSCLMGSEFSLPDAYLFVMVSWAKYFKLDLSQFEHLT
HHHHHHHHHHHHHHHHCCCEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KFMDLMLARPSVAKSLQQEKL
HHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MKLYYCRGACSLVVRIILNELGLNFQDEEVDLKVKKTAGGEDFFKINPKGAVPTLVLDNG
CEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEECCC
DVLTENQVILQYLADTTPGQKLLAAVGESKRYHTLEWLNYISTELHKSLGMFFNPTVSEE
CEEECHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IKSKILTPLVMTRFAYTNTRLAKGSCLMGSEFSLPDAYLFVMVSWAKYFKLDLSQFEHLT
HHHHHHHHHHHHHHHHCCCEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KFMDLMLARPSVAKSLQQEKL
HHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]