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The map label for this gene is gmhB [H]

Identifier: 54294726

GI number: 54294726

Start: 2017218

End: 2017748

Strand: Reverse

Name: gmhB [H]

Synonym: lpl1803

Alternate gene names: 54294726

Gene position: 2017748-2017218 (Counterclockwise)

Preceding gene: 54294727

Following gene: 54294725

Centisome position: 60.31

GC content: 39.17

Gene sequence:

>531_bases
ATGAATCGAATTATATTGCTTGATAGAGATGGAGTAATTAACACTGACTCAATCAATTATATTAAGAATGCTGATGAGCT
TATTATTATACCCGATAGCATTACTGCGATAGCTCGTTTATGTGCTGCCGGATATAAAATCGGTGTTGCAACCAATCAAT
CTGGAGTTTCAAGAGGGCTATACTCTGAGGATGATTTATCTGCCATTCATTGTAAGTTGAGAGAGGTGCTTGCAGAAGCA
GGGGGGCAAATTGACGCCTTAGAGTATTGTATCCATTTACCTGAGGACAACTGTTTTTGCCGAAAACCCCAGCCAGGAAT
GCTAAAGGCTCTGGCAGAAAAGTTAAATTGTTCACTGGATAGCGTGCCCTTTGTCGGGGATAGAGTTTCAGATATACATG
CAGCATTGGCAGTTGGTGCCCAGCCTATTATTGTACTTTCTAATATGACTGATATGTCTGAGTTGGCACAATATCCTAAA
GTACCAATTTATAATTCCCTGTTACAGTATGTCAATCAATTATTATTGTAA

Upstream 100 bases:

>100_bases
TGGTTGAGGAGGAGTCATTGAAACAGAACAGGCTTGCGCTCCTGCAGCGATTACAAGAGTTATTGCAGGGTGTAGCTGAC
ATTTCAATGTTGTAGCACTT

Downstream 100 bases:

>100_bases
GAATGAATAGAATAAAAGCAGTTGGTTATGAAAATAATGAACTCAAAGAAAAAGCACAATTGTTAGCTGATCAATTGAAT
TTACAGTTAGATCAAAATGC

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNRIILLDRDGVINTDSINYIKNADELIIIPDSITAIARLCAAGYKIGVATNQSGVSRGLYSEDDLSAIHCKLREVLAEA
GGQIDALEYCIHLPEDNCFCRKPQPGMLKALAEKLNCSLDSVPFVGDRVSDIHAALAVGAQPIIVLSNMTDMSELAQYPK
VPIYNSLLQYVNQLLL

Sequences:

>Translated_176_residues
MNRIILLDRDGVINTDSINYIKNADELIIIPDSITAIARLCAAGYKIGVATNQSGVSRGLYSEDDLSAIHCKLREVLAEA
GGQIDALEYCIHLPEDNCFCRKPQPGMLKALAEKLNCSLDSVPFVGDRVSDIHAALAVGAQPIIVLSNMTDMSELAQYPK
VPIYNSLLQYVNQLLL
>Mature_176_residues
MNRIILLDRDGVINTDSINYIKNADELIIIPDSITAIARLCAAGYKIGVATNQSGVSRGLYSEDDLSAIHCKLREVLAEA
GGQIDALEYCIHLPEDNCFCRKPQPGMLKALAEKLNCSLDSVPFVGDRVSDIHAALAVGAQPIIVLSNMTDMSELAQYPK
VPIYNSLLQYVNQLLL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=170, Percent_Identity=31.1764705882353, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=31.2056737588652, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19189; Mature: 19189

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIILLDRDGVINTDSINYIKNADELIIIPDSITAIARLCAAGYKIGVATNQSGVSRGL
CCEEEEEECCCCCCCCCCHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCHHHCCC
YSEDDLSAIHCKLREVLAEAGGQIDALEYCIHLPEDNCFCRKPQPGMLKALAEKLNCSLD
CCCCCHHHHHHHHHHHHHHCCCCEEHHHHEEECCCCCCEECCCCCHHHHHHHHHHCCCCC
SVPFVGDRVSDIHAALAVGAQPIIVLSNMTDMSELAQYPKVPIYNSLLQYVNQLLL
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIILLDRDGVINTDSINYIKNADELIIIPDSITAIARLCAAGYKIGVATNQSGVSRGL
CCEEEEEECCCCCCCCCCHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCHHHCCC
YSEDDLSAIHCKLREVLAEAGGQIDALEYCIHLPEDNCFCRKPQPGMLKALAEKLNCSLD
CCCCCHHHHHHHHHHHHHHCCCCEEHHHHEEECCCCCCEECCCCCHHHHHHHHHHCCCCC
SVPFVGDRVSDIHAALAVGAQPIIVLSNMTDMSELAQYPKVPIYNSLLQYVNQLLL
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]