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The map label for this gene is yciR [C]

Identifier: 54294243

GI number: 54294243

Start: 1463775

End: 1466153

Strand: Reverse

Name: yciR [C]

Synonym: lpl1308

Alternate gene names: 54294243

Gene position: 1466153-1463775 (Counterclockwise)

Preceding gene: 54294244

Following gene: 54294237

Centisome position: 43.82

GC content: 34.89

Gene sequence:

>2379_bases
ATGATTAATATTATTAAAAACAGAAACAAGAAAAACCATACTGCTTCCACTGAGTTGAAATCAGAAATTGAGAAGGAGCA
GGTCAAACTGCTTTTTGATCAAGTTGGTATGGCTATATCAGGTGAAGCTTTAGCAGTAACTATACTACCTATTGCATTAT
GGTCTGTTACAAATCATGAGCTGCTTATTATTTGGATGATTTTTACTTATGTTTTTTCAGATCTTTATAAAAGCATGCTG
CTCTTCCATTACAATAAACAACCAACATTATTTTCAACCGAAAAATGGTTGTTCCTTTTTAACTTGAGTGTTGCAAGCTC
TGGCTTGGCATGGGGATTTGCCAGTTCAATTATGATTCCAGCCTCAAGTACATTGCATCAAATCTTTGTCGTTTTTCTTA
TTACAGGAGTTACAGCAGCAGCCAATTCACTCTATTCACCTGTGCGATTATCCTATTTTTTATTTCTGGTCACTGCTTTT
GTTCCTTTCACTATATGGTTATTTTCAAAAGGACAAGTTTATTTATTGTTAGGGTTTTGTGGCATTATTTATATGGGGAT
TATGTTGTTTATTTCATATTACTCAAACAGGATTTTGATTAATACCTTAAAAATGCGCTTTAAAATCTCTAATTTGAATT
CAACCAAAGATATTTTAGAAAAAAAAGTAGTGGACAGAACCAAAGAATTGGAAAAAATCCTGGCTTTGACCAAATCAACT
TTAGAGTCAACAGCGGATGGTATTTTAGTTGTTGATCTCAAAGGTAATATTGAATTCTGCAATCAGCAATTTCTCAAGAT
GTGGGGAATTTCTCCAGGGTTTATTGAAAGTCATAATGACACAGAAACAATTCAATATGTATTGAATCAGCTTAAAAATC
CGGAAGAATTTTTAAAACAAATTAAAGAACTATACAATAATCCAAATCAGGAAAGCTTTGATGAATTGCATTTCAAAGAC
GGGAAAATCTTTGAGAGATACTCACAACCACATTGGTTAGACAATAAAATTATAGGACGTGTTTGGAGTTTTAGAGATGT
GACCTTAAGAACCAGATTAGCCTATCAAGCCAATCATGATTCTCTAACTGGTTTACCCAATCGTACAGCTCTATACGATC
GCCTGGATCATGCGATTAATTACTGTAAACGATTGAACACCTCATTATCAGTGTTATTTCTGGATATTGATAATTTTAAG
TTAATTAATGACAGCCTGGGCCATGATGCCGGTGATATATTATTGTATGAATTTTCCAGGCGTCTTAAAGGATGCATACG
TCATAGCGATACAGTTGCTCGATTTGGCGGTGATGAGTTTGTTTTGTTATTGATGACCACTGAACCTAAAGATGTTATTT
TAGTAGCACAAAACATTTTAAAGGCTGTAGCGCAACCTATCAAATTGCCTACCCAGGAAGTCATAGTGACGACAAGTATA
GGAATTAGCCTTTTCCCTAAAGATGGCATTGATGCAAGCACCTTACTCAAAAATTCCGATACCGCAATGTACCTGGCTAA
AAAGGAAGGGCGCAATAATTTCCAATTTTATAATAATTCGATCAATCAACAATCGCTCAAACGCCTTGAGATACAAACAC
AGATACATAATGCAATTAAAAATAATGAATTTTTTATTCTTTACCAGCCCATTTATAGTTTACGTAACGGTGAATTAGTA
GGTGCCGAAGCCCTGATACGTTGGGGGCATCCTGCAATAGGACTCCTCTCTCCGGATGAATTTATTCCTATTGCTGAAGA
AACCGGCTTGATTAACCAAGTGGGCGAGTGGGTCTTAAGAAATGCCTGTATTCAAAATAAAACCTGGCAGCTTATGGGGT
TACCGCATATTAGTATTTCTGTTAATGTCTCATGGAGACAGCTAAAAAATAGCAATTTTATCGAGATTGCAGAATCTGTA
TTAAAAGAATCCAGACTAGATCCTCAATATTTGGAAATTGAATTCACCGAAAGTACTATGATACAAAAATCAACGCCCAT
TGATTCGACGTTAATAAAAATTTCCCAGTTGGGCATTAAAATGGCAATTGATGATTTTGGTACCGGTTACTCAAATTTAA
GTTATTTAAAGACTTTCCCCTTCAATAAACTTAAAATTGATCGTTCATTTATTCAAAACTGCACCACTAACCCAAATGAT
GCCTCCATAGTTGAAGCAATTATTGCCATGGCCCATAGCCTGGAACTCAAAGTATTGGCAGAAGGAGTTGACACGATTGA
TAAAGCATTTTTTATGCATCAACATGGCTGTGATGAAGTACAAGGTTTCCTTTATGGCCTACCTGTTAAAGCTGATAAGT
TTGTGAAATTAATGCAAAAAACTAAAATCCGCCATTCAAAATTTATTAATAAAACATAA

Upstream 100 bases:

>100_bases
CACGATGCACTTAGTTTTATTTTCTAACTGTTTACGAGGAAAACAATCCACATTAATGCTCGCTTCGCTCTTTAACATAC
CATTTTACTAACTACTTGTT

Downstream 100 bases:

>100_bases
GGTTGTTGTTTCTTTTATTACTATAAAGAAAATACTACAGACTACTCATCAATTGAACTAGCTCATTTAAACCAGTATTT
TTAAACACACAACAAATTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MINIIKNRNKKNHTASTELKSEIEKEQVKLLFDQVGMAISGEALAVTILPIALWSVTNHELLIIWMIFTYVFSDLYKSML
LFHYNKQPTLFSTEKWLFLFNLSVASSGLAWGFASSIMIPASSTLHQIFVVFLITGVTAAANSLYSPVRLSYFLFLVTAF
VPFTIWLFSKGQVYLLLGFCGIIYMGIMLFISYYSNRILINTLKMRFKISNLNSTKDILEKKVVDRTKELEKILALTKST
LESTADGILVVDLKGNIEFCNQQFLKMWGISPGFIESHNDTETIQYVLNQLKNPEEFLKQIKELYNNPNQESFDELHFKD
GKIFERYSQPHWLDNKIIGRVWSFRDVTLRTRLAYQANHDSLTGLPNRTALYDRLDHAINYCKRLNTSLSVLFLDIDNFK
LINDSLGHDAGDILLYEFSRRLKGCIRHSDTVARFGGDEFVLLLMTTEPKDVILVAQNILKAVAQPIKLPTQEVIVTTSI
GISLFPKDGIDASTLLKNSDTAMYLAKKEGRNNFQFYNNSINQQSLKRLEIQTQIHNAIKNNEFFILYQPIYSLRNGELV
GAEALIRWGHPAIGLLSPDEFIPIAEETGLINQVGEWVLRNACIQNKTWQLMGLPHISISVNVSWRQLKNSNFIEIAESV
LKESRLDPQYLEIEFTESTMIQKSTPIDSTLIKISQLGIKMAIDDFGTGYSNLSYLKTFPFNKLKIDRSFIQNCTTNPND
ASIVEAIIAMAHSLELKVLAEGVDTIDKAFFMHQHGCDEVQGFLYGLPVKADKFVKLMQKTKIRHSKFINKT

Sequences:

>Translated_792_residues
MINIIKNRNKKNHTASTELKSEIEKEQVKLLFDQVGMAISGEALAVTILPIALWSVTNHELLIIWMIFTYVFSDLYKSML
LFHYNKQPTLFSTEKWLFLFNLSVASSGLAWGFASSIMIPASSTLHQIFVVFLITGVTAAANSLYSPVRLSYFLFLVTAF
VPFTIWLFSKGQVYLLLGFCGIIYMGIMLFISYYSNRILINTLKMRFKISNLNSTKDILEKKVVDRTKELEKILALTKST
LESTADGILVVDLKGNIEFCNQQFLKMWGISPGFIESHNDTETIQYVLNQLKNPEEFLKQIKELYNNPNQESFDELHFKD
GKIFERYSQPHWLDNKIIGRVWSFRDVTLRTRLAYQANHDSLTGLPNRTALYDRLDHAINYCKRLNTSLSVLFLDIDNFK
LINDSLGHDAGDILLYEFSRRLKGCIRHSDTVARFGGDEFVLLLMTTEPKDVILVAQNILKAVAQPIKLPTQEVIVTTSI
GISLFPKDGIDASTLLKNSDTAMYLAKKEGRNNFQFYNNSINQQSLKRLEIQTQIHNAIKNNEFFILYQPIYSLRNGELV
GAEALIRWGHPAIGLLSPDEFIPIAEETGLINQVGEWVLRNACIQNKTWQLMGLPHISISVNVSWRQLKNSNFIEIAESV
LKESRLDPQYLEIEFTESTMIQKSTPIDSTLIKISQLGIKMAIDDFGTGYSNLSYLKTFPFNKLKIDRSFIQNCTTNPND
ASIVEAIIAMAHSLELKVLAEGVDTIDKAFFMHQHGCDEVQGFLYGLPVKADKFVKLMQKTKIRHSKFINKT
>Mature_792_residues
MINIIKNRNKKNHTASTELKSEIEKEQVKLLFDQVGMAISGEALAVTILPIALWSVTNHELLIIWMIFTYVFSDLYKSML
LFHYNKQPTLFSTEKWLFLFNLSVASSGLAWGFASSIMIPASSTLHQIFVVFLITGVTAAANSLYSPVRLSYFLFLVTAF
VPFTIWLFSKGQVYLLLGFCGIIYMGIMLFISYYSNRILINTLKMRFKISNLNSTKDILEKKVVDRTKELEKILALTKST
LESTADGILVVDLKGNIEFCNQQFLKMWGISPGFIESHNDTETIQYVLNQLKNPEEFLKQIKELYNNPNQESFDELHFKD
GKIFERYSQPHWLDNKIIGRVWSFRDVTLRTRLAYQANHDSLTGLPNRTALYDRLDHAINYCKRLNTSLSVLFLDIDNFK
LINDSLGHDAGDILLYEFSRRLKGCIRHSDTVARFGGDEFVLLLMTTEPKDVILVAQNILKAVAQPIKLPTQEVIVTTSI
GISLFPKDGIDASTLLKNSDTAMYLAKKEGRNNFQFYNNSINQQSLKRLEIQTQIHNAIKNNEFFILYQPIYSLRNGELV
GAEALIRWGHPAIGLLSPDEFIPIAEETGLINQVGEWVLRNACIQNKTWQLMGLPHISISVNVSWRQLKNSNFIEIAESV
LKESRLDPQYLEIEFTESTMIQKSTPIDSTLIKISQLGIKMAIDDFGTGYSNLSYLKTFPFNKLKIDRSFIQNCTTNPND
ASIVEAIIAMAHSLELKVLAEGVDTIDKAFFMHQHGCDEVQGFLYGLPVKADKFVKLMQKTKIRHSKFINKT

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=429, Percent_Identity=38.4615384615385, Blast_Score=318, Evalue=1e-87,
Organism=Escherichia coli, GI87081921, Length=419, Percent_Identity=31.7422434367542, Blast_Score=238, Evalue=2e-63,
Organism=Escherichia coli, GI226510982, Length=419, Percent_Identity=29.8329355608592, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1790496, Length=258, Percent_Identity=32.5581395348837, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87081743, Length=258, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786507, Length=271, Percent_Identity=31.7343173431734, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1788502, Length=262, Percent_Identity=31.2977099236641, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87081980, Length=270, Percent_Identity=30.7407407407407, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=31.8897637795276, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081845, Length=271, Percent_Identity=28.4132841328413, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788849, Length=247, Percent_Identity=31.5789473684211, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788381, Length=595, Percent_Identity=23.5294117647059, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87082096, Length=439, Percent_Identity=25.0569476082005, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1786584, Length=167, Percent_Identity=34.1317365269461, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081977, Length=157, Percent_Identity=34.3949044585987, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI145693134, Length=170, Percent_Identity=33.5294117647059, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787816, Length=175, Percent_Identity=33.7142857142857, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=34.6820809248555, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=37.9310344827586, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=34.1317365269461, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788956, Length=175, Percent_Identity=35.4285714285714, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789650, Length=433, Percent_Identity=20.0923787528868, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=149, Percent_Identity=30.8724832214765, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787410, Length=126, Percent_Identity=31.7460317460317, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 90325; Mature: 90325

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIIKNRNKKNHTASTELKSEIEKEQVKLLFDQVGMAISGEALAVTILPIALWSVTNHE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEEHHHHHHCCCCC
LLIIWMIFTYVFSDLYKSMLLFHYNKQPTLFSTEKWLFLFNLSVASSGLAWGFASSIMIP
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCEEEEEEEHHHCCCCHHHHHCCEECC
ASSTLHQIFVVFLITGVTAAANSLYSPVRLSYFLFLVTAFVPFTIWLFSKGQVYLLLGFC
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEHHHHH
GIIYMGIMLFISYYSNRILINTLKMRFKISNLNSTKDILEKKVVDRTKELEKILALTKST
HHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LESTADGILVVDLKGNIEFCNQQFLKMWGISPGFIESHNDTETIQYVLNQLKNPEEFLKQ
HHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
IKELYNNPNQESFDELHFKDGKIFERYSQPHWLDNKIIGRVWSFRDVTLRTRLAYQANHD
HHHHHCCCCCCCHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHEEEECCCC
SLTGLPNRTALYDRLDHAINYCKRLNTSLSVLFLDIDNFKLINDSLGHDAGDILLYEFSR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHCCCCCCHHHHHHHHH
RLKGCIRHSDTVARFGGDEFVLLLMTTEPKDVILVAQNILKAVAQPIKLPTQEVIVTTSI
HHHHHHHCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEEEC
GISLFPKDGIDASTLLKNSDTAMYLAKKEGRNNFQFYNNSINQQSLKRLEIQTQIHNAIK
CEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHC
NNEFFILYQPIYSLRNGELVGAEALIRWGHPAIGLLSPDEFIPIAEETGLINQVGEWVLR
CCCEEEEEECHHHCCCCCEECHHHHHHCCCCCEECCCCCCCCCCHHHCCHHHHHHHHHHH
NACIQNKTWQLMGLPHISISVNVSWRQLKNSNFIEIAESVLKESRLDPQYLEIEFTESTM
HHHHCCCCEEEEECCEEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHH
IQKSTPIDSTLIKISQLGIKMAIDDFGTGYSNLSYLKTFPFNKLKIDRSFIQNCTTNPND
CCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCHHEECCCCCEEECHHHHHCCCCCCCH
ASIVEAIIAMAHSLELKVLAEGVDTIDKAFFMHQHGCDEVQGFLYGLPVKADKFVKLMQK
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
TKIRHSKFINKT
HHHHHHHCCCCC
>Mature Secondary Structure
MINIIKNRNKKNHTASTELKSEIEKEQVKLLFDQVGMAISGEALAVTILPIALWSVTNHE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEEHHHHHHCCCCC
LLIIWMIFTYVFSDLYKSMLLFHYNKQPTLFSTEKWLFLFNLSVASSGLAWGFASSIMIP
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCEEEEEEEHHHCCCCHHHHHCCEECC
ASSTLHQIFVVFLITGVTAAANSLYSPVRLSYFLFLVTAFVPFTIWLFSKGQVYLLLGFC
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEHHHHH
GIIYMGIMLFISYYSNRILINTLKMRFKISNLNSTKDILEKKVVDRTKELEKILALTKST
HHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LESTADGILVVDLKGNIEFCNQQFLKMWGISPGFIESHNDTETIQYVLNQLKNPEEFLKQ
HHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
IKELYNNPNQESFDELHFKDGKIFERYSQPHWLDNKIIGRVWSFRDVTLRTRLAYQANHD
HHHHHCCCCCCCHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHEEEECCCC
SLTGLPNRTALYDRLDHAINYCKRLNTSLSVLFLDIDNFKLINDSLGHDAGDILLYEFSR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHCCCCCCHHHHHHHHH
RLKGCIRHSDTVARFGGDEFVLLLMTTEPKDVILVAQNILKAVAQPIKLPTQEVIVTTSI
HHHHHHHCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEEEC
GISLFPKDGIDASTLLKNSDTAMYLAKKEGRNNFQFYNNSINQQSLKRLEIQTQIHNAIK
CEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHC
NNEFFILYQPIYSLRNGELVGAEALIRWGHPAIGLLSPDEFIPIAEETGLINQVGEWVLR
CCCEEEEEECHHHCCCCCEECHHHHHHCCCCCEECCCCCCCCCCHHHCCHHHHHHHHHHH
NACIQNKTWQLMGLPHISISVNVSWRQLKNSNFIEIAESVLKESRLDPQYLEIEFTESTM
HHHHCCCCEEEEECCEEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHH
IQKSTPIDSTLIKISQLGIKMAIDDFGTGYSNLSYLKTFPFNKLKIDRSFIQNCTTNPND
CCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCHHEECCCCCEEECHHHHHCCCCCCCH
ASIVEAIIAMAHSLELKVLAEGVDTIDKAFFMHQHGCDEVQGFLYGLPVKADKFVKLMQK
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
TKIRHSKFINKT
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]