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The map label for this gene is holA [H]

Identifier: 54294234

GI number: 54294234

Start: 1449995

End: 1451020

Strand: Reverse

Name: holA [H]

Synonym: lpl1299

Alternate gene names: 54294234

Gene position: 1451020-1449995 (Counterclockwise)

Preceding gene: 54294235

Following gene: 54294233

Centisome position: 43.37

GC content: 32.36

Gene sequence:

>1026_bases
ATGCAAATAAATCAACAAGCTCTTACTCAGCTTTTACAAAAAAAAATACCTCATCTTAATGTACTAATTGGACAAGATCA
TTATCTTATTGACGAAGCACTCAATAACATAAAATCAATGCTTAAAAAATCATCTGAATGTGATGAGAAAATCCTATCTA
TTCAGTCCCCTGAAGAATGGCATGTCGTTCTGGAAGAAACAAATAATTACTCTCTTTTTTATCAAACAGTTATTTTAACC
ATTTTCTTTGATAAAAAAACGATAGATACAATGGGGAAAAAAATTCTTAGTGAATATCTCAAATCAGCCAACTCTCATAG
TTATATTATTATCAGAGCCCCTAACCTTACCGCCAAGCAACTTCAATGGTTAACACATGATGAACAAGCGCTGATTATCA
TTGCACAACCATTAAGCTCAGAAGCAATGAAGAGATGGATTAATGAGCAATTAAAATTAAATACTATCTCTTTCGATCCA
TATGTTCCTGAATTAATTTATCAATATACTAAAGGAAATATGCTAGCTACCGCTCAGGTAATTGAAAAAATTACTTTGAG
CAATACACCCGGCACTCTCATTACTCCTTACCTGGCCTTGGAACATTTATCGGATCAATGTGATTTTTCCCTTTTTGAAC
TGATTGATTCATGTCTACTTGGTCATAGCGACAGAGCAATCCATATTTTAAGACAAGCTGCCAATAATAAAACAGAAGTC
ACATTGGTATTATGGATGCTTACCCAAGAAATAAGAACGCTATTACAATTATTATTTCTAATGCAACAAAAGATGGATAT
CAAAATAGCATCTAATCAATTAAAAATTTGGACTCAAAGAGTTAATCTTTATCAATCCGCTGTTAAAAGATTAAACACTT
CACTTTTACAACAACTTCATCACTATTGCCAATCTATTGATGATAAAATCAAATCCAACTCAAACAATCAAGTATGGAAT
GCTCTAGAGAACATTTCTCTTTCCTTATGTTTAGGGCAATTACTAGGTGATGCATGCATAGCATAG

Upstream 100 bases:

>100_bases
GACAGGATATTAGGGTCAAATGAAGAACAAGCTCTTTTAGTCAGCGAAATGAGGCGTGATGCCGCTATTCAAATCATTAA
TCGTTTAAACCGACCATGAT

Downstream 100 bases:

>100_bases
CAATATTTGGTGGAACATTTGACCCAGTGCATAATGGTCATATCAAGACCAGCTTAGCAATTCAAGCTAACTTTGGCTTT
GATTCCTATTATTTTTTACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MQINQQALTQLLQKKIPHLNVLIGQDHYLIDEALNNIKSMLKKSSECDEKILSIQSPEEWHVVLEETNNYSLFYQTVILT
IFFDKKTIDTMGKKILSEYLKSANSHSYIIIRAPNLTAKQLQWLTHDEQALIIIAQPLSSEAMKRWINEQLKLNTISFDP
YVPELIYQYTKGNMLATAQVIEKITLSNTPGTLITPYLALEHLSDQCDFSLFELIDSCLLGHSDRAIHILRQAANNKTEV
TLVLWMLTQEIRTLLQLLFLMQQKMDIKIASNQLKIWTQRVNLYQSAVKRLNTSLLQQLHHYCQSIDDKIKSNSNNQVWN
ALENISLSLCLGQLLGDACIA

Sequences:

>Translated_341_residues
MQINQQALTQLLQKKIPHLNVLIGQDHYLIDEALNNIKSMLKKSSECDEKILSIQSPEEWHVVLEETNNYSLFYQTVILT
IFFDKKTIDTMGKKILSEYLKSANSHSYIIIRAPNLTAKQLQWLTHDEQALIIIAQPLSSEAMKRWINEQLKLNTISFDP
YVPELIYQYTKGNMLATAQVIEKITLSNTPGTLITPYLALEHLSDQCDFSLFELIDSCLLGHSDRAIHILRQAANNKTEV
TLVLWMLTQEIRTLLQLLFLMQQKMDIKIASNQLKIWTQRVNLYQSAVKRLNTSLLQQLHHYCQSIDDKIKSNSNNQVWN
ALENISLSLCLGQLLGDACIA
>Mature_341_residues
MQINQQALTQLLQKKIPHLNVLIGQDHYLIDEALNNIKSMLKKSSECDEKILSIQSPEEWHVVLEETNNYSLFYQTVILT
IFFDKKTIDTMGKKILSEYLKSANSHSYIIIRAPNLTAKQLQWLTHDEQALIIIAQPLSSEAMKRWINEQLKLNTISFDP
YVPELIYQYTKGNMLATAQVIEKITLSNTPGTLITPYLALEHLSDQCDFSLFELIDSCLLGHSDRAIHILRQAANNKTEV
TLVLWMLTQEIRTLLQLLFLMQQKMDIKIASNQLKIWTQRVNLYQSAVKRLNTSLLQQLHHYCQSIDDKIKSNSNNQVWN
ALENISLSLCLGQLLGDACIA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the b

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786859, Length=284, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39168; Mature: 39168

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINQQALTQLLQKKIPHLNVLIGQDHYLIDEALNNIKSMLKKSSECDEKILSIQSPEEW
CCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
HVVLEETNNYSLFYQTVILTIFFDKKTIDTMGKKILSEYLKSANSHSYIIIRAPNLTAKQ
EEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
LQWLTHDEQALIIIAQPLSSEAMKRWINEQLKLNTISFDPYVPELIYQYTKGNMLATAQV
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCEEHHHHH
IEKITLSNTPGTLITPYLALEHLSDQCDFSLFELIDSCLLGHSDRAIHILRQAANNKTEV
HHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
TLVLWMLTQEIRTLLQLLFLMQQKMDIKIASNQLKIWTQRVNLYQSAVKRLNTSLLQQLH
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYCQSIDDKIKSNSNNQVWNALENISLSLCLGQLLGDACIA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQINQQALTQLLQKKIPHLNVLIGQDHYLIDEALNNIKSMLKKSSECDEKILSIQSPEEW
CCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
HVVLEETNNYSLFYQTVILTIFFDKKTIDTMGKKILSEYLKSANSHSYIIIRAPNLTAKQ
EEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
LQWLTHDEQALIIIAQPLSSEAMKRWINEQLKLNTISFDPYVPELIYQYTKGNMLATAQV
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCEEHHHHH
IEKITLSNTPGTLITPYLALEHLSDQCDFSLFELIDSCLLGHSDRAIHILRQAANNKTEV
HHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
TLVLWMLTQEIRTLLQLLFLMQQKMDIKIASNQLKIWTQRVNLYQSAVKRLNTSLLQQLH
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYCQSIDDKIKSNSNNQVWNALENISLSLCLGQLLGDACIA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8505303; 1400251; 8905232; 9278503; 3316191; 8505304; 1575709 [H]