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The map label for this gene is rhtC [H]

Identifier: 54294155

GI number: 54294155

Start: 1359804

End: 1360463

Strand: Reverse

Name: rhtC [H]

Synonym: lpl1219

Alternate gene names: 54294155

Gene position: 1360463-1359804 (Counterclockwise)

Preceding gene: 54294159

Following gene: 54294152

Centisome position: 40.66

GC content: 34.85

Gene sequence:

>660_bases
ATGGAACAATGGCATCAATTTACTCTACTATTCCCTTTAATCATTTTAGTTTTTATTTCATTAATTAGTCCTGGGCCAGA
TTTTGCTATCACGGTCAAAAACAGCTTAGCTTATTCCAGAAGGAGTGGTTTATTAACCGCGTTAGGAATTGCTTTGGGCA
GTTTGGTTCATATCAGTTACACTCTTCTTGGATTAGGCTTGTTTATTACTAAAACACCTGTAATACTGCATATCATCCAA
TATCTAGGGGCTGGATACCTCTTTTATATTGGCCTTAAAAATCTTGGTGCCAAGCCAAATGCTGACCAAATAGGAAGTTA
TACAACGTACAACGATTTAAAACCAAGTGAAGCTTTTTTCAATGGGTTTATAACGAATTTATTGAACCCAAAAGCCATGC
TCTTTTTTATCAGTTTGTTTTCAGTACTTATGCCCAGAGAAATTTCAATCTCCAATAAATTATTCCTGGCAATTATCCTT
TTTCTACAAACATTGTTATGGTTTTCTTTTGTTGCATTCAGTCTTTCTGGAAAAAATACGCGTACGAAATTTCAAAGAGT
TAGCTATTGGATTGAGCGTATTACAGGTGTCATTTTAATTGGATTGGCATTAAAGTTGCTATTAAGCCAATTGGGGTCTG
TTGATATTTCACCTGCTTGA

Upstream 100 bases:

>100_bases
GATAAACAATGTCTTATTAACTAAATGTAAATTAAAAAAGAGCGCTTAAAAATTAGCTATGATATTGGCTGAAAAAACTT
AGTAAAAATTTGGAGTTTCT

Downstream 100 bases:

>100_bases
GTCGAAAAGCCTTGATTTTCGAGCACCGTAGCGGAGCACAGAAAATCAAGGCTTTTCGGTCAAGATAGTAGAAATGTCAA
CAGACCTTAGTCTAATGGCC

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPVILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYTTYNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREISISNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIGLALKLLLSQLGSVDISPA

Sequences:

>Translated_219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPVILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYTTYNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREISISNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIGLALKLLLSQLGSVDISPA
>Mature_219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPVILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYTTYNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREISISNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIGLALKLLLSQLGSVDISPA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=205, Percent_Identity=30.7317073170732, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786522, Length=193, Percent_Identity=31.0880829015544, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788099, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24357; Mature: 24357

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISY
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGLGLFITKTPVILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTTYNDLKPSEAFF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCHHHCCCCCCCCCCCHHHHHH
NGFITNLLNPKAMLFFISLFSVLMPREISISNKLFLAIILFLQTLLWFSFVAFSLSGKNT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RTKFQRVSYWIERITGVILIGLALKLLLSQLGSVDISPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISY
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGLGLFITKTPVILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTTYNDLKPSEAFF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCHHHCCCCCCCCCCCHHHHHH
NGFITNLLNPKAMLFFISLFSVLMPREISISNKLFLAIILFLQTLLWFSFVAFSLSGKNT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RTKFQRVSYWIERITGVILIGLALKLLLSQLGSVDISPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]