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The map label for this gene is neuB

Identifier: 54293736

GI number: 54293736

Start: 895459

End: 896481

Strand: Direct

Name: neuB

Synonym: lpl0789

Alternate gene names: NA

Gene position: 895459-896481 (Clockwise)

Preceding gene: 54293735

Following gene: 54293737

Centisome position: 26.76

GC content: 38.91

Gene sequence:

>1023_bases
ATGACTTGTTTTATTATTGCTGAAGCAGGAGTAAACCATAATGGTGATCTTCAACTGGCTAAAGAATTAGTTTATGCAGC
CAAAGAGTCAGGAGCTGATGCAGTAAAGTTTCAGACTTTCAAAGCGGACACCTTGGTTAATAAAACAGTAGGAAAAGCGG
AATACCAAAAAAATAATGCCCCGGAATCCGCTACCCAGTATGAGATGCTCAAGGCACTGGAGCTTTCAGAAGATGACCAT
TATTTACTAAGTGAATTAGCCAATTCATTCGGCATTGAATTTATGTCAACTGGTTTTGATGAACAAAGCATCGATTTTCT
TATTTCTTTAGGGGTAAAGCGATTAAAAATTCCTTCTGGTGAAATTACCAACATCCCATATTTAAAGCATTGCGCCAGTA
AAAAATTACCCTTAATCATCTCAACAGGGATGTGCGATCTACAAGAAGTAAGAGTAGCCATAGATACAGTTAAACCCTAC
TATGGAAACTCTTTATTCGATTATCTGGTTTTGTTACATTGTACCTCTAATTATCCGGCAGCTTATCAAGACGTGAATTT
GAAAGCCATGCAGACATTAGCCGACGAATTTCAATTGCCAGTAGGTTATTCCGATCATACTTTAGGTATTTTGGTGCCAA
CATTAGCAGTAGGAATGGGGGCGTGCGTTATCGAAAAGCACTTTACAATCGATAAATCTCTTCCTGGCCCAGATCATCTG
GCTTCTATGAATCCAGAGGAAATGAAGAATTTAGTACAATCCATTAGAGACGCTGAAACTGTTTTGGGAAGTGGTGAAAA
AAAACCGTCGGATAATGAGCTGCCTATAAGAGCTCTGGTCAGAAGAAGTATTACTTTAAGGCGTGATTTGGTGAAAGGAG
CACAAATCAGTAAAGAAGATTTGATCTTGCTAAGACCTGGTACTGGGATAGCGCCCTCTGAAATATCAAATATTGTAGGC
GCTCGATTAAGTATGAATTTGTCTGCGGGTACTACTTTGTTATGGGAACATATTGAAGCGTAA

Upstream 100 bases:

>100_bases
CTTTATTGTTAAATAGTATTAGTGAATCCATCGACATCGATACGCCAATCGATTGGGCTTTAACAGAAAAATTAATGGAA
TTAAACCAAGAGGCTCTAGT

Downstream 100 bases:

>100_bases
TGACCAGAAAAATAATTTATGTTACAGGTACTCGTGCCGATTATGGACTGATGCGAGAAGTACTAAAAAGATTACACCAG
TCAGAAGACATTGACTTATC

Product: N-acetylneuraminic acid condensing enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTCFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVGKAEYQKNNAPESATQYEMLKALELSEDDH
YLLSELANSFGIEFMSTGFDEQSIDFLISLGVKRLKIPSGEITNIPYLKHCASKKLPLIISTGMCDLQEVRVAIDTVKPY
YGNSLFDYLVLLHCTSNYPAAYQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTIDKSLPGPDHL
ASMNPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKGAQISKEDLILLRPGTGIAPSEISNIVG
ARLSMNLSAGTTLLWEHIEA

Sequences:

>Translated_340_residues
MTCFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVGKAEYQKNNAPESATQYEMLKALELSEDDH
YLLSELANSFGIEFMSTGFDEQSIDFLISLGVKRLKIPSGEITNIPYLKHCASKKLPLIISTGMCDLQEVRVAIDTVKPY
YGNSLFDYLVLLHCTSNYPAAYQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTIDKSLPGPDHL
ASMNPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKGAQISKEDLILLRPGTGIAPSEISNIVG
ARLSMNLSAGTTLLWEHIEA
>Mature_339_residues
TCFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVGKAEYQKNNAPESATQYEMLKALELSEDDHY
LLSELANSFGIEFMSTGFDEQSIDFLISLGVKRLKIPSGEITNIPYLKHCASKKLPLIISTGMCDLQEVRVAIDTVKPYY
GNSLFDYLVLLHCTSNYPAAYQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTIDKSLPGPDHLA
SMNPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKGAQISKEDLILLRPGTGIAPSEISNIVGA
RLSMNLSAGTTLLWEHIEA

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=340, Percent_Identity=35, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21357081, Length=364, Percent_Identity=32.1428571428571, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37262; Mature: 37131

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVGKAEYQKNNA
CEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCHHHHHCCCC
PESATQYEMLKALELSEDDHYLLSELANSFGIEFMSTGFDEQSIDFLISLGVKRLKIPSG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCHHEEECCCC
EITNIPYLKHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLFDYLVLLHCTSNYPA
CCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
AYQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTIDKSLPGPDHL
CHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHEEECCCEECCCCCCCHHH
ASMNPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKGAQISKED
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
LILLRPGTGIAPSEISNIVGARLSMNLSAGTTLLWEHIEA
EEEECCCCCCCHHHHHHHHHHHEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
TCFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVGKAEYQKNNA
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCHHHHHCCCC
PESATQYEMLKALELSEDDHYLLSELANSFGIEFMSTGFDEQSIDFLISLGVKRLKIPSG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCHHEEECCCC
EITNIPYLKHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLFDYLVLLHCTSNYPA
CCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
AYQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTIDKSLPGPDHL
CHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHEEECCCEECCCCCCCHHH
ASMNPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKGAQISKED
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
LILLRPGTGIAPSEISNIVGARLSMNLSAGTTLLWEHIEA
EEEECCCCCCCHHHHHHHHHHHEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]