Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 54293712

GI number: 54293712

Start: 868821

End: 869777

Strand: Direct

Name: thiL [H]

Synonym: lpl0765

Alternate gene names: 54293712

Gene position: 868821-869777 (Clockwise)

Preceding gene: 54293711

Following gene: 54293713

Centisome position: 25.97

GC content: 42.11

Gene sequence:

>957_bases
ATGAATGAATTTACCCTGATTGATCATTATTTTAAATCCATCCCATACAAGAGAAATGATGTCCTTTTTGGGATAGGGGA
TGATGCTGCTTGCTTGCAGATTCCCGATGGAATGCATTTGCTAGTCAGCACGGATACTTTGGTTTCAGGCATTCATTTTC
TACCGCAATGGGATCCCTATGATATTGCCCGCAAGGCAGTAATGGTCAATATTAGTGACATGGCTGCCATGGGCGCACAG
CCATGTTGGGTGACTCTTGCATTGACCTTGCCCGAATTGAATCAGAGTTGGCTTGATTCCTTCGCGAGAGGGATAAAAGA
CTCTCTTGGCTTATATAATGTGGATCTGATCGGTGGTGATACGACCAAAGGCCCGTTATCAATCACTTTGACCATTATGG
GGCTCACACCTCAGGGACAAGCAATCAGACGTTGTGGCGCACAAGCGGGTGACGTGATTATGGTTTCCGGTGAATTGGGG
GCTGCGGGTCTGGCTGTAAAATTGCTGGATGGGCATAAAAAAGTGAATGCAAAAGATAAAATAGAATTAATGAATAAACT
ATTACATCCCAAACCACGGGTGGATTTATGCCATATGCTTAGAAAATATGCTACTTCAGCGATTGATATCTCTGATGGCT
TAGGCGCTGATTTAAATCATATTTGCGTCGCAAGTGGTGTTGGGGCTAACTTGTTTGAAGAAGCAATACCCAGGCATCCT
TTATTGAATCAATATTGTCCTGAACAAGCCCTTGACTTGGCTCTTTCAGGAGGTGATGATTACGAGTTATGTTTTACAGT
TTCAACACAACAGCTGGATTCTTTTAATCGGGATCTTAAAAAAGAAAATCTGATCTGTTTTCCAATTGGTGTGATAGAGG
AGAAACCAGGATTAAGAATACAATCAGCTGATAGTCCAAGTAAAGAATTGCAACCCAGAGGCTATTCACATTTTTAA

Upstream 100 bases:

>100_bases
TTGACTAAAGAGTTTGGTTCACAAGAGGGATATCGTTACGTTAATGGGGTATTGAATAATTTGGCAAAACAGGTTCGCTC
TGTTGAAGTCAGTCTTGATA

Downstream 100 bases:

>100_bases
ATCCCGCCTCTATAGTATGATAATAAAAATTAAAGACAAAATTCAATTCTAAAGTGATGTGATAGCGATATTTAGGTTGA
GGAGCAAATATGAACCAAGT

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNEFTLIDHYFKSIPYKRNDVLFGIGDDAACLQIPDGMHLLVSTDTLVSGIHFLPQWDPYDIARKAVMVNISDMAAMGAQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDVIMVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHMLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLKKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF

Sequences:

>Translated_318_residues
MNEFTLIDHYFKSIPYKRNDVLFGIGDDAACLQIPDGMHLLVSTDTLVSGIHFLPQWDPYDIARKAVMVNISDMAAMGAQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDVIMVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHMLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLKKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF
>Mature_318_residues
MNEFTLIDHYFKSIPYKRNDVLFGIGDDAACLQIPDGMHLLVSTDTLVSGIHFLPQWDPYDIARKAVMVNISDMAAMGAQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDVIMVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHMLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLKKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=324, Percent_Identity=46.9135802469136, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34720; Mature: 34720

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFTLIDHYFKSIPYKRNDVLFGIGDDAACLQIPDGMHLLVSTDTLVSGIHFLPQWDPY
CCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHCCCCCHH
DIARKAVMVNISDMAAMGAQPCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGD
HHHCEEEEEEEHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
TTKGPLSITLTIMGLTPQGQAIRRCGAQAGDVIMVSGELGAAGLAVKLLDGHKKVNAKDK
CCCCCEEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHH
IELMNKLLHPKPRVDLCHMLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
HHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLKKENLICFPIGVIEEKPGLRI
CHHHHCCHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEE
QSADSPSKELQPRGYSHF
ECCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNEFTLIDHYFKSIPYKRNDVLFGIGDDAACLQIPDGMHLLVSTDTLVSGIHFLPQWDPY
CCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHCCCCCHH
DIARKAVMVNISDMAAMGAQPCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGD
HHHCEEEEEEEHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
TTKGPLSITLTIMGLTPQGQAIRRCGAQAGDVIMVSGELGAAGLAVKLLDGHKKVNAKDK
CCCCCEEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHH
IELMNKLLHPKPRVDLCHMLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
HHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLKKENLICFPIGVIEEKPGLRI
CHHHHCCHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEE
QSADSPSKELQPRGYSHF
ECCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]