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The map label for this gene is hutI [H]

Identifier: 54293695

GI number: 54293695

Start: 848561

End: 849772

Strand: Direct

Name: hutI [H]

Synonym: lpl0748

Alternate gene names: 54293695

Gene position: 848561-849772 (Clockwise)

Preceding gene: 54293694

Following gene: 54293696

Centisome position: 25.36

GC content: 41.34

Gene sequence:

>1212_bases
ATGTTTGCCTGTGATGAATTATTGCTCAATGCAAGCACAATCGATGCCACAGGGTTGCAACTTTATAATCAAGCCATTGT
TATAAGAAAAGGCAGAATAGAGTGGTGTGGTTCTGAGGACCAGCTACCTGTCCATTTTCAGGAAAGTGCCAAGTCAAGAA
AGGATTGTCACGGCCAATTAATTACACCAGGATTAATTGATTGTCATACTCATCTGGTTTATGCAGGCCACAGAGCCGCA
GAGTTTCGATTAAAATCGCAAGGCGTCAGTTACGCTGATATCGCCAAATCAGGCGGGGGCATATTATCCACAGTACAAAT
GACACGAGATGCCTCTGAAGAAGAGTTAATTGATCAATCATTGCCAAGACTTCTTGCGCTAAAAAATGAAGGGGTTACTA
CTGTTGAAATTAAGTCAGGCTACGGCCTTGATTTGCAAAATGAATTGAAAATGCTCAGGGTTGCCAGGCAGTTAGGGGAC
ATGGCTGGAGTCAGGGTAAAAACAACTTTTCTGGGGGCGCATGCTGTAGGTCCAGAGTTTAAAGGAAATAGTCAGGCTTA
TGTCGATTTTCTTTGTAATGAAATGTTGCCTGCAGCTAAAAATATGGATTTGGTAGATGCCGTGGATGTTTTTTGTGAAT
CCATAGCTTTTTCTATAAGGCAGGCTGAGCAAATTTTTCAAGCTGCTAAGAATTTAAATTTACCAATAAAATGCCATGCT
GAACAATTATCTAATATGGGGGCCAGTTCTTTGGCTGCTCGTTATGGTGCGTTATCCTGTGATCATCTGGAGTTTTTGGA
TGAAAACGGCGCTTTAAATATGGTAAAAGCTAATACAGTTGCTGTCTTACTTCCTGGCGCTTTTTATTTCCTTAAAGAAA
AACAAAAACCACCTGTTGATTTATTGCGTCAGGTTGGTGTTGGTATGGCCATTGCCACGGATTCTAACCCGGGTTCCTCT
CCAACGACTTCTTTGTTATTGATGATGAGTATGGCTTGCCAATTTTTCTCTATGTCTATACCTGAAGTTTTATCTGCAGT
AACGTATCAGGCTTCCAGAGCTTTAGGAATGGAAAAGGATATTGGGAGCATTGAAGCAGGCAAGATTGCTGATTTGGTTT
TATGGTCTATAAAAGATAGCGCTGCGCTATGTTATTATTTCGCTTATCCGTTACCTCATCAAACGATGGTGGCTGGTGAA
TGGGTATCCTGA

Upstream 100 bases:

>100_bases
ATAATGAAACGTATGTATCCAAAGAGTGGGATATATATGACACGACTCACCACTCTGCCTGGTTGAAACCGCCTCACCAG
GTACTTCATTGGGAATTTTA

Downstream 100 bases:

>100_bases
GAGGATTACTTGATTGGAGATAAACAATGCCGATACAAATGAATTTAATCAATAAAATTGGCCTGATGTTTGGGCTATTA
TTTTATTCGTTTCTTGCTTC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQLITPGLIDCHTHLVYAGHRAA
EFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQSLPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGD
MAGVRVKTTFLGAHAVGPEFKGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHA
EQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVDLLRQVGVGMAIATDSNPGSS
PTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKDIGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGE
WVS

Sequences:

>Translated_403_residues
MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQLITPGLIDCHTHLVYAGHRAA
EFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQSLPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGD
MAGVRVKTTFLGAHAVGPEFKGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHA
EQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVDLLRQVGVGMAIATDSNPGSS
PTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKDIGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGE
WVS
>Mature_403_residues
MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQLITPGLIDCHTHLVYAGHRAA
EFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQSLPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGD
MAGVRVKTTFLGAHAVGPEFKGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHA
EQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVDLLRQVGVGMAIATDSNPGSS
PTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKDIGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGE
WVS

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=369, Percent_Identity=38.4823848238482, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17555004, Length=354, Percent_Identity=32.4858757062147, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 43799; Mature: 43799

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQL
CCCHHHHHHCCCCCCHHHHHHHCEEEEEECCCEEECCCCCCCCEEHHHHHCHHHCCCCCC
ITPGLIDCHTHLVYAGHRAAEFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQS
CCCCHHHHHHHEEEECCCHHHEEEHHCCCCHHHHHCCCCCEEEEHHHHHCCCHHHHHHHH
LPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGDMAGVRVKTTFLGAHAVGPEF
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
KGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECH
EQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVD
HHHHCCCHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCEEEHHCCCCCCHH
LLRQVGVGMAIATDSNPGSSPTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKD
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
IGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGEWVS
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEEECCCCCC
>Mature Secondary Structure
MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQL
CCCHHHHHHCCCCCCHHHHHHHCEEEEEECCCEEECCCCCCCCEEHHHHHCHHHCCCCCC
ITPGLIDCHTHLVYAGHRAAEFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQS
CCCCHHHHHHHEEEECCCHHHEEEHHCCCCHHHHHCCCCCEEEEHHHHHCCCHHHHHHHH
LPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGDMAGVRVKTTFLGAHAVGPEF
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
KGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECH
EQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVD
HHHHCCCHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCEEEHHCCCCCCHH
LLRQVGVGMAIATDSNPGSSPTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKD
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
IGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGEWVS
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA