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The map label for this gene is yugS [H]

Identifier: 54293594

GI number: 54293594

Start: 697413

End: 698732

Strand: Direct

Name: yugS [H]

Synonym: lpl0646

Alternate gene names: 54293594

Gene position: 697413-698732 (Clockwise)

Preceding gene: 54293590

Following gene: 54293597

Centisome position: 20.85

GC content: 36.89

Gene sequence:

>1320_bases
ATGTATAACATTCTGTTAATTTTTTTAGCATTCCTGCTGGTGCTTCTCAATGCATTTTTTGTATCGGCCGAATTTGGGAT
GGTTAAACTCAGGGCTACGAGAATTCAAGCCATCAAAGAAAACTACGGGCTAAGAGGTCGCATTCTTGAGCAAGTCCATC
AAAATCTCGATGCGTATTTATCAGCATGTCAGTTAGGCATTACTCTTGCTTCGTTAGGATTGGGTTGGATTGGAGAGCCT
GCTTTTGCGGAGTTATTGGGGCCATTATTTGTTGCTTTGGGTATTTCATCGGTTCATATTGTTACTATATCTTCTTTTTT
TATTGCATTTTTTCTTATTTCTTTTCTACATATTGTAATCGGTGAGCTCATGCCCAAGTCCATTGCCATTCGGCAATCTG
AATTGATTTCAATATGGACTGCAGTCCCATTGTATTGGTTTTACTGGATAATGTATCCTGCCATTTGGTTGTTAAATACA
TGTTCCAATTTTTTTCTCAAACTGTCCGGCATGGATATAAAAAATGAATACGAAGGTTTTTATTCAAGTGAGGAACTTAA
ATTAATTTTAAGCGGACAGCATCTGCAATCGGAATTAAAAGAGGATGAACGTGAAATCCTGGAGCATACTCTCGATTTGG
CTGAGTTAAATGTCACTGAGGTAATGCGCCCTGAAGATGAAATGATCATAATAGATATCAATGAGCCATTCGAAACGAGT
AAAGATAAAATTTTAAAATATCGTTATAGTCGTTATCCTGTCTATGATTCCGGGACTAGGGAAATGATTGGTGTCATCCA
TGTTAAGGATTTATTTGCCGATTTGTTGCTCCAGAAAAATATCAATACATTAAAGCCTTATGTACGGCCAGTACTTAAAG
TCAGTCATAAATTACCTGCTATGGATTTGCTGCGCAAATTTCGAGCAGGTATGCCTCATTTTGCTTTGGTATACAAACAC
AAATCGAGTTTACTTGGATTTGTAACTCTGGATAATTTGCTCCATATCCTGATTGGGCGGATTAAAGACGAGTTTCATAA
AACACATGAAGATTGGGTAAAAAATGCGGACGGAACTATAACGACAAAAGGAGATTGCTCCCTTTATTCTCTAGAAAGGG
CTCTTGATTGCGATATTACTTTATCGCCAGATGAAGAAGAACTGAATACACTATATGGACTTATTATCACGCGCCACGGA
AAATTGCCCAATGAAGGTGAAATAATTCAATTTGTTGAATTTGATGCCTTGATTGAAAAGGTACAGGATTCTTTTATAAC
CAAAATTAAAGTTTTCCCCAAGATCAAAAACCAGGAATAA

Upstream 100 bases:

>100_bases
TTTATATAAACCAAATGACCGAATTATAAATATTTTTAACGAAGAGATTGGGATTTTTCGTAAGTTCTGTGAAATTAAAT
CATAAACCGGACTATTTTTA

Downstream 100 bases:

>100_bases
TATTTGCTCCGCGGTATAAAAGGCCAACTGGAGACCTTTTATACCTGGTTCATTTAATCCAAGGTTGACATATCGATAAC
AAATCGATATTTCACATCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MYNILLIFLAFLLVLLNAFFVSAEFGMVKLRATRIQAIKENYGLRGRILEQVHQNLDAYLSACQLGITLASLGLGWIGEP
AFAELLGPLFVALGISSVHIVTISSFFIAFFLISFLHIVIGELMPKSIAIRQSELISIWTAVPLYWFYWIMYPAIWLLNT
CSNFFLKLSGMDIKNEYEGFYSSEELKLILSGQHLQSELKEDEREILEHTLDLAELNVTEVMRPEDEMIIIDINEPFETS
KDKILKYRYSRYPVYDSGTREMIGVIHVKDLFADLLLQKNINTLKPYVRPVLKVSHKLPAMDLLRKFRAGMPHFALVYKH
KSSLLGFVTLDNLLHILIGRIKDEFHKTHEDWVKNADGTITTKGDCSLYSLERALDCDITLSPDEEELNTLYGLIITRHG
KLPNEGEIIQFVEFDALIEKVQDSFITKIKVFPKIKNQE

Sequences:

>Translated_439_residues
MYNILLIFLAFLLVLLNAFFVSAEFGMVKLRATRIQAIKENYGLRGRILEQVHQNLDAYLSACQLGITLASLGLGWIGEP
AFAELLGPLFVALGISSVHIVTISSFFIAFFLISFLHIVIGELMPKSIAIRQSELISIWTAVPLYWFYWIMYPAIWLLNT
CSNFFLKLSGMDIKNEYEGFYSSEELKLILSGQHLQSELKEDEREILEHTLDLAELNVTEVMRPEDEMIIIDINEPFETS
KDKILKYRYSRYPVYDSGTREMIGVIHVKDLFADLLLQKNINTLKPYVRPVLKVSHKLPAMDLLRKFRAGMPHFALVYKH
KSSLLGFVTLDNLLHILIGRIKDEFHKTHEDWVKNADGTITTKGDCSLYSLERALDCDITLSPDEEELNTLYGLIITRHG
KLPNEGEIIQFVEFDALIEKVQDSFITKIKVFPKIKNQE
>Mature_439_residues
MYNILLIFLAFLLVLLNAFFVSAEFGMVKLRATRIQAIKENYGLRGRILEQVHQNLDAYLSACQLGITLASLGLGWIGEP
AFAELLGPLFVALGISSVHIVTISSFFIAFFLISFLHIVIGELMPKSIAIRQSELISIWTAVPLYWFYWIMYPAIWLLNT
CSNFFLKLSGMDIKNEYEGFYSSEELKLILSGQHLQSELKEDEREILEHTLDLAELNVTEVMRPEDEMIIIDINEPFETS
KDKILKYRYSRYPVYDSGTREMIGVIHVKDLFADLLLQKNINTLKPYVRPVLKVSHKLPAMDLLRKFRAGMPHFALVYKH
KSSLLGFVTLDNLLHILIGRIKDEFHKTHEDWVKNADGTITTKGDCSLYSLERALDCDITLSPDEEELNTLYGLIITRHG
KLPNEGEIIQFVEFDALIEKVQDSFITKIKVFPKIKNQE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=403, Percent_Identity=32.7543424317618, Blast_Score=225, Evalue=6e-59,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=23.3333333333333, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790664, Length=415, Percent_Identity=20.2409638554217, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87082033, Length=279, Percent_Identity=27.2401433691756, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1786879, Length=212, Percent_Identity=25.4716981132075, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=24.0506329113924, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50388; Mature: 50388

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNILLIFLAFLLVLLNAFFVSAEFGMVKLRATRIQAIKENYGLRGRILEQVHQNLDAYL
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SACQLGITLASLGLGWIGEPAFAELLGPLFVALGISSVHIVTISSFFIAFFLISFLHIVI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELMPKSIAIRQSELISIWTAVPLYWFYWIMYPAIWLLNTCSNFFLKLSGMDIKNEYEGF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCC
YSSEELKLILSGQHLQSELKEDEREILEHTLDLAELNVTEVMRPEDEMIIIDINEPFETS
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCC
KDKILKYRYSRYPVYDSGTREMIGVIHVKDLFADLLLQKNINTLKPYVRPVLKVSHKLPA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
MDLLRKFRAGMPHFALVYKHKSSLLGFVTLDNLLHILIGRIKDEFHKTHEDWVKNADGTI
HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
TTKGDCSLYSLERALDCDITLSPDEEELNTLYGLIITRHGKLPNEGEIIQFVEFDALIEK
EECCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHH
VQDSFITKIKVFPKIKNQE
HHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MYNILLIFLAFLLVLLNAFFVSAEFGMVKLRATRIQAIKENYGLRGRILEQVHQNLDAYL
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SACQLGITLASLGLGWIGEPAFAELLGPLFVALGISSVHIVTISSFFIAFFLISFLHIVI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELMPKSIAIRQSELISIWTAVPLYWFYWIMYPAIWLLNTCSNFFLKLSGMDIKNEYEGF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCC
YSSEELKLILSGQHLQSELKEDEREILEHTLDLAELNVTEVMRPEDEMIIIDINEPFETS
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCC
KDKILKYRYSRYPVYDSGTREMIGVIHVKDLFADLLLQKNINTLKPYVRPVLKVSHKLPA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
MDLLRKFRAGMPHFALVYKHKSSLLGFVTLDNLLHILIGRIKDEFHKTHEDWVKNADGTI
HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
TTKGDCSLYSLERALDCDITLSPDEEELNTLYGLIITRHGKLPNEGEIIQFVEFDALIEK
EECCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHH
VQDSFITKIKVFPKIKNQE
HHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]