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The map label for this gene is coaD

Identifier: 54293539

GI number: 54293539

Start: 638818

End: 639330

Strand: Direct

Name: coaD

Synonym: lpl0590

Alternate gene names: 54293539

Gene position: 638818-639330 (Clockwise)

Preceding gene: 54293536

Following gene: 54293540

Centisome position: 19.09

GC content: 34.89

Gene sequence:

>513_bases
ATGCAAATGGTAATTAACGAGATGAAACAAAAAGCAATCTACCCTGGAACATTTGACCCTGTAACCAATGGCCACATTGA
TATTATTACTCGGGCCAGCACTATTTTTCCTGAATTAATAGTTGCTGTAGCGAGTAATAAAAACAAGCGGCCTTATTTAT
CTTGGGAAAGCAGAATTAGTTTACTGGAAGAGTCCGTTGGACATTTAACTGGCGTGAGAGTTGTGGGTTTTGATAATTTG
CTAATTGATTTTGTATTAGAACAAAACGCAGGCATTATTTTACGTGGATTGAGAGCTGTTTCTGATTTTGAATATGAATT
TCAACTGGCTGGAATGAACAGAAAACTATCTAAAAAGGTAGAGACATTATTTTTAACCCCCGCAGAGCATTTAATGTATA
TCTCATCCACTTTAGTTCGTGAAATTGCAGCCTTAAATGGTGATATTTCTCAATTTGTTCCACCCAATGTAGTTAGAGAA
TTAAAAAAGAGACAAAATGAAAGATCATTATAA

Upstream 100 bases:

>100_bases
CAAATTAAAATGATTGTCAAACGTTTTATCACATTCATTGCTTACCTCAATTCCATTTTTTTATAGTTTTTCAATTTACA
ATACGCTAGACTGCTTCTAT

Downstream 100 bases:

>100_bases
ATGGCTGGGTTGTTTATTTTTTTTAATTTGTAATATTTATCAAGTTAATGCAAAAACATTTCCGCAACACCCGCCTGGAT
ATGCTGTAGCAAGTGCCCAC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWESRISLLEESVGHLTGVRVVGFDNL
LIDFVLEQNAGIILRGLRAVSDFEYEFQLAGMNRKLSKKVETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRE
LKKRQNERSL

Sequences:

>Translated_170_residues
MQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWESRISLLEESVGHLTGVRVVGFDNL
LIDFVLEQNAGIILRGLRAVSDFEYEFQLAGMNRKLSKKVETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRE
LKKRQNERSL
>Mature_170_residues
MQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWESRISLLEESVGHLTGVRVVGFDNL
LIDFVLEQNAGIILRGLRAVSDFEYEFQLAGMNRKLSKKVETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRE
LKKRQNERSL

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=48.4076433121019, Blast_Score=177, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_LEGPH (Q5ZY26)

Other databases:

- EMBL:   AE017354
- RefSeq:   YP_094590.1
- ProteinModelPortal:   Q5ZY26
- SMR:   Q5ZY26
- STRING:   Q5ZY26
- GeneID:   3080128
- GenomeReviews:   AE017354_GR
- KEGG:   lpn:lpg0548
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- ProtClustDB:   PRK00168
- BioCyc:   LPNE272624:LPG0548-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19232; Mature: 19232

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWESRIS
CCHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LLEESVGHLTGVRVVGFDNLLIDFVLEQNAGIILRGLRAVSDFEYEFQLAGMNRKLSKKV
HHHHHHHHHHCEEEECHHHHHHHHHHHCCCCEEHHHHHHHHCCCEEEEEECCCHHHHHHH
ETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRELKKRQNERSL
HHHEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWESRIS
CCHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LLEESVGHLTGVRVVGFDNLLIDFVLEQNAGIILRGLRAVSDFEYEFQLAGMNRKLSKKV
HHHHHHHHHHCEEEECHHHHHHHHHHHCCCCEEHHHHHHHHCCCEEEEEECCCHHHHHHH
ETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRELKKRQNERSL
HHHEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA