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The map label for this gene is sucC [H]

Identifier: 54293529

GI number: 54293529

Start: 628052

End: 629215

Strand: Direct

Name: sucC [H]

Synonym: lpl0580

Alternate gene names: 54293529

Gene position: 628052-629215 (Clockwise)

Preceding gene: 54293528

Following gene: 54293530

Centisome position: 18.77

GC content: 39.86

Gene sequence:

>1164_bases
ATGAATTTACATGAATATCAAGCCAAGCAATTGTTCGCTAGCTATGGTTTACCAGTTCCTCGTGGTGAGGTCGCTTATAA
TGTTGAGGATGCCTTGCTCGTTGCTTCTCAATTATCAACCTCTCGATGGGTTGTGAAAGCACAAGTCCATGCTGGTGGAA
GAGGTAAAGCAGGTGGTGTGAAACTGGTTTCTAGCAAAGATGAATTGGCTGCAGTTGCGAAATCCATGTTAGGCACACGT
CTGGTTACTTATCAAACTGATGCCAGAGGCCAACCGGTTAATGCTATTTTGGTTGAAGAAACCTGCGAAATAGACAAGGA
ATTATATCTTGGTGCTGTTGTTGATAGATCCACCAGACGAGTTGTTATTATGGCCTCTACAGAAGGTGGTGTTGAAATTG
AAAAGGTTGCTCATGAAACACCTGAGAAAATTTTCAAGGTGGTTGTTGATCCCTTAGTTGGTGTTATGCCTTTTCAATGT
CGTGAAACAGCTTTTAAACTTGGATTAAAAGACGATCAAATCAAACAATTCACTCATTTGATGATGGGATTAGGGAAAAT
GTTTGTTGATTGTGATTTAAGTTTATTAGAGATAAATCCGCTTGTCATAACAAAATCAGGGCAACTAATTTGTCTGGATG
GAAAAATTAATATCGATGGAAATGCTTTATTCCGACAGCCTAAACTGAAAAATATGCGAGACGTTTCCCAGGAAGATGAT
CGAGAAAATCGTGCTAGTGATTGGGAGCTTAATTATATTCCTTTGGATGGGACAATAGGTTGCATGGTAAATGGTGCTGG
TTTGGCTATGGCTACCATGGACGTGATAAAATTACATGGTGGTGAGCCGGCTAATTTCCTGGATGTTGGGGGAGGCGCCA
CAAAAGAAAGAGTCAGTGAAGCTTTGAAGATTATTGTGTCAGATGAAAAAGTCAAAGGAATTCTAGTTAATATTTTTGGT
GGAATCGTTCGTTGTGACCTTATTGCTGATGGAATTCTTGCTGCTGTAAAAGAAGTGGATGTAAAAATTCCTGTTGTTGT
CAGACTGGAAGGTAATAATGCCCAGCTAGGTGCTGAGATATTGAATAAAAGCAATTTAAATGTGATTGCTGCAACGAGTT
TGACAGACGCAGCCAAGAAAATTGTAGCAGCAGTTTCCGAATAA

Upstream 100 bases:

>100_bases
TGTTGGAAGATCCATCTCGACTTTTACTGAATGTTTAATGAGTCATGTTTAACTGCAAGACCCGTCTTGACGGGTTTTGC
TTTTTTAAAAGGTAATTAGA

Downstream 100 bases:

>100_bases
AGAATAAATTAATTTTGGCATTATTGGTAAGGTAGTTTTCAAAGCGGATATGCCATTAAATTACGAGGTTAACAATGAGT
GTATTAGTTGATAAACATAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTR
LVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQC
RETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDD
RENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFG
GIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE

Sequences:

>Translated_387_residues
MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTR
LVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQC
RETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDD
RENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFG
GIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE
>Mature_387_residues
MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTR
LVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQC
RETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDD
RENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFG
GIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=46.0154241645244, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.3864229765013, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=44.6927374301676, Blast_Score=297, Evalue=1e-80,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=70.6493506493507, Blast_Score=541, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=46.6494845360825, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=41.8781725888325, Blast_Score=309, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=42.0918367346939, Blast_Score=328, Evalue=7e-91,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=45.0632911392405, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=44.4155844155844, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=44.4155844155844, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=44.8186528497409, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=44.8186528497409, Blast_Score=306, Evalue=1e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41724; Mature: 41724

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVSSKDELAAVAKSMLGTRLVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRR
EEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECHHCCCHHHEEEHEECCCCCE
VVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQCRETAFKLGLKDDQIKQFTHL
EEEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
MMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDD
HHHHHHHEEECCCEEEEECEEEEECCCCEEEECCEEEECCCEEECCCCCCHHHCCCCCCC
RENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSE
CCCCCCCCEEEEEECCCCEEEEEECCCHHHHHEEHHEECCCCCCCEEECCCCCCHHHHHH
ALKIIVSDEKVKGILVNIFGGIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEI
HHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHH
LNKSNLNVIAATSLTDAAKKIVAAVSE
HCCCCCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVSSKDELAAVAKSMLGTRLVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRR
EEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECHHCCCHHHEEEHEECCCCCE
VVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQCRETAFKLGLKDDQIKQFTHL
EEEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
MMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDD
HHHHHHHEEECCCEEEEECEEEEECCCCEEEECCEEEECCCEEECCCCCCHHHCCCCCCC
RENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSE
CCCCCCCCEEEEEECCCCEEEEEECCCHHHHHEEHHEECCCCCCCEEECCCCCCHHHHHH
ALKIIVSDEKVKGILVNIFGGIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEI
HHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHH
LNKSNLNVIAATSLTDAAKKIVAAVSE
HCCCCCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA