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The map label for this gene is fabZ [H]

Identifier: 54293499

GI number: 54293499

Start: 597671

End: 598123

Strand: Direct

Name: fabZ [H]

Synonym: lpl0548

Alternate gene names: 54293499

Gene position: 597671-598123 (Clockwise)

Preceding gene: 54293498

Following gene: 54293500

Centisome position: 17.86

GC content: 39.74

Gene sequence:

>453_bases
ATGAACGAATCGATAGATATAAATCAAATTTTTACTTTGTTACCACACCGCTACCCATTTATTCTGGTTGATAGAGTGAT
AGATTACAAAGTAATGGAATATTTGATTGCAATCAAAAATGTGACTATTAATGAGAACTTCTTTACCGGGCATTTTCCAG
GGAATCCTATTATGCCTGGGGTACTAATGCTTGAGGCTTTAGCCCAAGCTAGCGGCATTTTAGCCAATTTGTCTCGCCAA
CCCAAAGAGGGGTATGAATTTCTGCATTATTTTGCCGGTATTGACAATGCTCGGTTCAAGCAAGTAGTGATTCCTGGGGA
TCAACTGCGATTAGAGGTGAGACTGGTTGGGCAAAAAAGAGATTTTTGGCGTATGCACGGAGAAGCTTATATCGGTGATA
AATTAGCTTGTTCCGCAGACTTGTTGAGCGCAACAAAGGAAATTAAAAAGTGA

Upstream 100 bases:

>100_bases
GAAGTAACATTATTTTTGAAATTTTTAATTGATTAGAATGAGCTAAACCAAGATAATGAGCCATTTTGTAATGCAATAGG
CGATTAATGAGAACTAGGGT

Downstream 100 bases:

>100_bases
TAGATGAAAGAGCAATGATTCACCCTTCGGCGAAGCTGGCAAGCGGAGTGTCAATAGGCCCCGGAACAGTAATAGGCGCT
GATGTTGAGATTGGTGAAAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQASGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLVGQKRDFWRMHGEAYIGDKLACSADLLSATKEIKK

Sequences:

>Translated_150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQASGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLVGQKRDFWRMHGEAYIGDKLACSADLLSATKEIKK
>Mature_150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQASGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLVGQKRDFWRMHGEAYIGDKLACSADLLSATKEIKK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=51.7482517482517, Blast_Score=153, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17142; Mature: 17142

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCEEECCCCCCCCCHH
VLMLEALAQASGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLVGQKR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCC
DFWRMHGEAYIGDKLACSADLLSATKEIKK
HHHHHCCCEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCEEECCCCCCCCCHH
VLMLEALAQASGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLVGQKR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCC
DFWRMHGEAYIGDKLACSADLLSATKEIKK
HHHHHCCCEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA