| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is uvrA [H]
Identifier: 54293378
GI number: 54293378
Start: 474359
End: 477214
Strand: Direct
Name: uvrA [H]
Synonym: lpl0427
Alternate gene names: 54293378
Gene position: 474359-477214 (Clockwise)
Preceding gene: 54293369
Following gene: 54293379
Centisome position: 14.18
GC content: 42.96
Gene sequence:
>2856_bases ATGCATACCATCACCATTCGTGGCGCAAGAACCCATAATCTCAAGAACTTGGACCTGGAGCTTCCTCGAGATAAATTAAT CGTAATAACCGGATTGTCTGGTTCTGGGAAGTCGTCTTTAGCCTTTGATACTCTCTATGCCGAAGGCCAGCGCCGTTACG TGGAATCTTTGTCTGCTTATGCTCGACAATTTTTGTCCATGATGGAAAAACCTGATGTTGATTCGATAGAGGGGCTATCC CCGGCGATTTCTATAGAACAAAAGGCTACCTCTCATAATCCCCGATCTACTGTAGGCACCATTACCGAAATTTATGACTA TTTGCGCTTGCTTTATGCCCGAGTCGGAGAGCCAAGATGTCCTACCCACCACACCAGCTTGCATGCTCAGACCATTAGCC AAATGGTTGACCAGGTATTGGCTTTACCAGAAGACAGTAAAGTGATGATTCTGGCGCCTGTTATTCGTGAACGGAAGGGA GAGCATGTCCAGTTTTTGCAACAATTGCAAGCCCAGGGGTACGTACGTGCACGTATTGATGGAGAGCTTTATGAACTGGA TTCTCCCCCTAAATTAGGATTGCGCACCAAGCACACTATTGAAGTAGTTATTGATCGTTTTAAAGTGCGCCCTGATTTGG CTCAACGTTTGAGTGAATCTTTTGAAAATGCGCTCAATCTGGCAGATGGCCTTGCCATCGTTTCTTCAATGGATGGTCAT TTCAAGGAACTTTTATTTTCTTCCAGGTTTGCATGCTCTGAATGCGGTTACAGTTTAAGTGAACTTGAGCCAAGGCTTTT TTCATTTAACAATCCTGTCGGTGCGTGTTCCTCATGTGATGGGCTTGGAGTGGATCAGTTTTTTGATCCGTCAAGAGTAG TCCACGATGCAACCGCCAGTTTGGCAGAAGGGGCAATCAGGGGATGGGATAGGAAAACCACGTATTATTTCAGCATGCTT GAGTCGCTTGCGAGACACTATGGTTTTGATACCAGTACGCCTTTTTGTGATTTAAGTGAAGCAATGCAACAAATCGTTTT GTATGGTAGTGGTCGTGAAATAATCGAGTTTCAGTATCATAGGCCGCATGGAGGATACATGGTGAAGCGGCATAGTTTTG AGGGAATAATTCCTAACATGCAACGCCGCTATCGTGAATCAGATTCTGGTATGATAAGGGAGGAACTTGCCAAATACCTA TCCTCACGCCCTTGCCAATCTTGTCAGGGAGCAAGATTACGTGAAGAAGCTCGACATGTATTTATTGATAATAAAAATCT ACCAGAAATCACCAGCTATTCTATTGAGCAAGCCTATCAGTTTTTTAAAGAGCTGAAGTTATCGGGATATAGGGGTGAAA TTGCAGCAAAAATCAATAAGGAAATTGTTGAGCGGCTGGGGTTTCTGGTGAATGTCGGGCTGGATTATTTGTCTTTGGCT CGAAGCGCGGAGACTCTATCTGGCGGAGAAGCTCAACGTATTCGCCTGGCTAGTCAAATAGGTTCAGGGCTTGTAGGGGT GATGTATATTTTGGATGAGCCTTCAATAGGGCTGCACCAACGTGACAACGACCGATTATTGAGTACTTTAATGCATTTAC GCAACCAGGGGAACACAGTAATCGTTGTGGAACATGATGAAGATGCTATCCGAAGCGCTGATTTTGTTCTTGATATAGGA CCTGGGGCTGGAGTGCATGGTGGGGAAGTAGTTGCCAGCGGTTCTCCTGAAGAGGTAATGAACAATCCCGCATCTCTCAC CGGCCAATATTTGTCTGGGAAAAAGGAAATAGAAATTCCCAAGGATCGAATTCCGGTTAACCATGATCGGATGATTCATT TAAAAGGCGTGTCTTGCAATAATTTACAAAATGTTGATATCAGTATTCCTTTAGGTTTGTTGACTTGTATTACAGGTGTT TCTGGTTCAGGTAAATCCAGTTTGATTAATGATACTTTATATCCTATTGCTGCCAATGCACTAAACAGAGCCAGCTTAAT GACTATAGGTGAGGTTAAGGACATTTCTGGACTGCATCTTTGTGACAAGGTTATTGACATCGACCAGAGTCCAATTGGCA GAACCCCGCGTTCCAATCCGGCAACTTATACTGGTTTATTTACTCATATCAGAGATTTATTCTCAGGGACTCCGGAATCA AGAGCACGAGGGTATCAACCTGGGCGCTTTAGTTTCAATGTAAAAGGTGGCCGGTGCGAAGCTTGTCAAGGTGATGGTCT TATCAAGGTTGAAATGCATTTTTTACCTGATATATACGTTTCTTGTGATGTATGCCAAGGCAAAAGATACAATAGGGAAA CTTTGGAAATTCACTACAAAGGCAAAAATATTCACGAAGTGTTAGACATGACTGTCGAAGATGCGTGCGCTTTTTTTGCT GCCATTCCTGTTATTGCCAGAAAATGCCAAACATTAATGGATGTCGGTTTGTCTTATATAAAGCTGGGACAAAGTGCAAC TACTCTCTCTGGAGGAGAAGCTCAAAGGATCAAGTTGGCTAGAGAATTATCAAAAAGGGATACCGGAAATACACTGTATA TTCTCGATGAGCCCACAACAGGATTACACTTTCATGACACGAAACAGCTATTAACTGTGTTGACTCGCTTGCGAGGGCAA GGAAATACCATTGTCATTATTGAACATAATTTGGATGTGATAAAAACGGCTGATTGGATCGTTGATCTTGGTCCTGAAGG AGGCAGTAAAGGGGGAAAGATTATTGCAACAGGAACCCCCGAAATGGTTGCTGAAAATCCTCAATCTTTTACCGGCCAGT TTTTAAAACAAATTTTATCAAAATCAAATGAGCTTCTATTACAGAAATGCAAATAG
Upstream 100 bases:
>100_bases TTTCATATTAAAATCCCTATTTCGCATCATAGTGTGCAATTTGTTTTATTATTATAGCAGAGATATACTCATGTATTTTT AAGTCAAATTAGCGAATTTT
Downstream 100 bases:
>100_bases TTCATTAATTATCAATTTGTCTTTATACTTGATGTGCTATCCAGGTTGTTTTTCAGGCAACCTGAATCTCTTTTTGTGAC AAAAAACACGTTATCCAGTT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 951; Mature: 951
Protein sequence:
>951_residues MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSMMEKPDVDSIEGLS PAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRCPTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKG EHVQFLQQLQAQGYVRARIDGELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATASLAEGAIRGWDRKTTYYFSML ESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYHRPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYL SSRPCQSCQGARLREEARHVFIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTVIVVEHDEDAIRSADFVLDIG PGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIPKDRIPVNHDRMIHLKGVSCNNLQNVDISIPLGLLTCITGV SGSGKSSLINDTLYPIAANALNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYKGKNIHEVLDMTVEDACAFFA AIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLARELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLRGQ GNTIVIIEHNLDVIKTADWIVDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLKQILSKSNELLLQKCK
Sequences:
>Translated_951_residues MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSMMEKPDVDSIEGLS PAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRCPTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKG EHVQFLQQLQAQGYVRARIDGELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATASLAEGAIRGWDRKTTYYFSML ESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYHRPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYL SSRPCQSCQGARLREEARHVFIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTVIVVEHDEDAIRSADFVLDIG PGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIPKDRIPVNHDRMIHLKGVSCNNLQNVDISIPLGLLTCITGV SGSGKSSLINDTLYPIAANALNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYKGKNIHEVLDMTVEDACAFFA AIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLARELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLRGQ GNTIVIIEHNLDVIKTADWIVDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLKQILSKSNELLLQKCK >Mature_951_residues MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSMMEKPDVDSIEGLS PAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRCPTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKG EHVQFLQQLQAQGYVRARIDGELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATASLAEGAIRGWDRKTTYYFSML ESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYHRPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYL SSRPCQSCQGARLREEARHVFIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTVIVVEHDEDAIRSADFVLDIG PGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIPKDRIPVNHDRMIHLKGVSCNNLQNVDISIPLGLLTCITGV SGSGKSSLINDTLYPIAANALNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYKGKNIHEVLDMTVEDACAFFA AIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLARELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLRGQ GNTIVIIEHNLDVIKTADWIVDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLKQILSKSNELLLQKCK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=71.2765957446808, Blast_Score=1386, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 105411; Mature: 105411
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSMMEKPDVDSIEGLSPAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRC HHHHHHHHCCCCCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKGEHVQFLQQLQAQGYVRARID CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH CEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATAS HHHHHHHCCCCHHHHCCCHHHCCCHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHH LAEGAIRGWDRKTTYYFSMLESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYH HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEEE RPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYLSSRPCQSCQGARLREEARHV CCCCCEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHCCEE FIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTV HHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEE IVVEHDEDAIRSADFVLDIGPGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIP EEEECCCHHHHCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCHHHCHHHHCCCCCCCCC KDRIPVNHDRMIHLKGVSCNNLQNVDISIPLGLLTCITGVSGSGKSSLINDTLYPIAANA HHCCCCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH LNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES HCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEEEEC GKNIHEVLDMTVEDACAFFAAIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHH RELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLRGQGNTIVIIEHNLDVIKTADWI HHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCEE VDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLKQILSKSNELLLQKCK EEECCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCC >Mature Secondary Structure MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSMMEKPDVDSIEGLSPAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRC HHHHHHHHCCCCCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKGEHVQFLQQLQAQGYVRARID CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH CEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATAS HHHHHHHCCCCHHHHCCCHHHCCCHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHH LAEGAIRGWDRKTTYYFSMLESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYH HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEEE RPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYLSSRPCQSCQGARLREEARHV CCCCCEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHCCEE FIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTV HHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEE IVVEHDEDAIRSADFVLDIGPGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIP EEEECCCHHHHCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCHHHCHHHHCCCCCCCCC KDRIPVNHDRMIHLKGVSCNNLQNVDISIPLGLLTCITGVSGSGKSSLINDTLYPIAANA HHCCCCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH LNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES HCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEEEEC GKNIHEVLDMTVEDACAFFAAIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHH RELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLRGQGNTIVIIEHNLDVIKTADWI HHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCEE VDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLKQILSKSNELLLQKCK EEECCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10984043 [H]