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The map label for this gene is yjbC [C]

Identifier: 54020392

GI number: 54020392

Start: 244385

End: 245107

Strand: Reverse

Name: yjbC [C]

Synonym: mhp215

Alternate gene names: 54020392

Gene position: 245107-244385 (Counterclockwise)

Preceding gene: 54020393

Following gene: 54020391

Centisome position: 27.46

GC content: 29.05

Gene sequence:

>723_bases
ATGAAAAAAATCAGAATTAACAAATTTTTATCGGAAATGGGGGTTTGCTCGCGTAGGCAATCTGAGAAATTAATTTTACA
GGGTCGGATAAAAATAAATAACGAAACTGCGAAAATTGGACAAATAGTTAGTCAAAATGATGTAATTGAACTTGATCAGC
AAAAAATTACTAAAAAACCACCAATTTTTTGATATGCATTAAATAAGCCAAAAAATTACATTACAAGCCGGTTTGATCCA
GAAAATAGACCAACAATAATGGAATTTTTTAGTAAAAATGAATATCTTTTTCCTGTTGGAAGATTAGATTTCCAAACTAC
CGGGTTAATTTTGATCACAAATGATGGAAAAACTACAAATAAATTATTACATCCAAGCTCAAAAATCGAGAGAACATATT
TAGTAAAAACAGATTTTAGTCTCAGTGATAAAGAAATTCGCTTCTTAAATGATAATAAAATCCAACTTGATAGTGTTAAA
TCCATCCAAAAAATTAAAAAATGTAGCTCCAGAACTTACCTTGTAACAGTTTGGCAAGGGTCTAACCATCATATCAAAAA
ACTATTTTTGTCAATAAATAAAAAAGTTCTAAAGCTGAAAAGGGTAAGTTTTGCAAATATTAAACTAAATAACATCAGCG
AGGGCAAGTACCGAAAACTAACAAATCAAGAAATTAAATCACTCGAGAATCAAGTAAAAAATACGACTAGATTAGGTGAC
TAA

Upstream 100 bases:

>100_bases
TTACACGGTCTTAATGCTTTAGTTATGGTAAAAAATCACCCAAATCGCCTAGTATGTGTGAATATACCAGTAAAATTATT
AAAAAATCAACTAGGAAATT

Downstream 100 bases:

>100_bases
AAAATTAAAAATTTACATCAATTTACGTATTCTTTTTGATTTTTATATTAAATTTTTTGATATAAAAATCAAAAAGAATA
GGAAAAATTTCCCTCGCAAC

Product: ribosomal large subunit pseudouridine synthase B

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKKIRINKFLSEMGVCSRRQSEKLILQGRIKINNETAKIGQIVSQNDVIELDQQKITKKPPIFWYALNKPKNYITSRFDP
ENRPTIMEFFSKNEYLFPVGRLDFQTTGLILITNDGKTTNKLLHPSSKIERTYLVKTDFSLSDKEIRFLNDNKIQLDSVK
SIQKIKKCSSRTYLVTVWQGSNHHIKKLFLSINKKVLKLKRVSFANIKLNNISEGKYRKLTNQEIKSLENQVKNTTRLGD

Sequences:

>Translated_240_residues
MKKIRINKFLSEMGVCSRRQSEKLILQGRIKINNETAKIGQIVSQNDVIELDQQKITKKPPIF*YALNKPKNYITSRFDP
ENRPTIMEFFSKNEYLFPVGRLDFQTTGLILITNDGKTTNKLLHPSSKIERTYLVKTDFSLSDKEIRFLNDNKIQLDSVK
SIQKIKKCSSRTYLVTVWQGSNHHIKKLFLSINKKVLKLKRVSFANIKLNNISEGKYRKLTNQEIKSLENQVKNTTRLGD
>Mature_240_residues
MKKIRINKFLSEMGVCSRRQSEKLILQGRIKINNETAKIGQIVSQNDVIELDQQKITKKPPIF*YALNKPKNYITSRFDP
ENRPTIMEFFSKNEYLFPVGRLDFQTTGLILITNDGKTTNKLLHPSSKIERTYLVKTDFSLSDKEIRFLNDNKIQLDSVK
SIQKIKKCSSRTYLVTVWQGSNHHIKKLFLSINKKVLKLKRVSFANIKLNNISEGKYRKLTNQEIKSLENQVKNTTRLGD

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=235, Percent_Identity=33.1914893617021, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787524, Length=230, Percent_Identity=30.8695652173913, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788510, Length=232, Percent_Identity=27.5862068965517, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 27777; Mature: 27777

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRINKFLSEMGVCSRRQSEKLILQGRIKINNETAKIGQIVSQNDVIELDQQKITKKP
CCEEHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCEEEECHHHHCCCC
PIFYALNKPKNYITSRFDPENRPTIMEFFSKNEYLFPVGRLDFQTTGLILITNDGKTTNK
CEEEEECCCHHHHCCCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCEEEEECCCCCCHH
LLHPSSKIERTYLVKTDFSLSDKEIRFLNDNKIQLDSVKSIQKIKKCSSRTYLVTVWQGS
EECCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEHHHHHHHHHHHHCCCEEEEEEEECC
NHHIKKLFLSINKKVLKLKRVSFANIKLNNISEGKYRKLTNQEIKSLENQVKNTTRLGD
CHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIRINKFLSEMGVCSRRQSEKLILQGRIKINNETAKIGQIVSQNDVIELDQQKITKKP
CCEEHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCEEEECHHHHCCCC
PIFYALNKPKNYITSRFDPENRPTIMEFFSKNEYLFPVGRLDFQTTGLILITNDGKTTNK
CEEEEECCCHHHHCCCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCEEEEECCCCCCHH
LLHPSSKIERTYLVKTDFSLSDKEIRFLNDNKIQLDSVKSIQKIKKCSSRTYLVTVWQGS
EECCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEHHHHHHHHHHHHCCCEEEEEEEECC
NHHIKKLFLSINKKVLKLKRVSFANIKLNNISEGKYRKLTNQEIKSLENQVKNTTRLGD
CHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]