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The map label for this gene is yrbE [H]

Identifier: 54020368

GI number: 54020368

Start: 180183

End: 181202

Strand: Reverse

Name: yrbE [H]

Synonym: mhp150

Alternate gene names: 54020368

Gene position: 181202-180183 (Counterclockwise)

Preceding gene: 54020369

Following gene: 54020367

Centisome position: 20.3

GC content: 30.59

Gene sequence:

>1020_bases
ATGAAATTTAAAGTCGGAATCATCGGCGGAGGAAGAATTGGCTATGTCCATACTCACGCAATTAATAAATTTGTTGATGA
TGCTAAAGTAATTGCAATTGCTGATGCTTATTTAGATAGCCAAAATCAGGAAAAATTTAGGAAATTAGGAGTAAAAAGTT
TTTATAGTGACTATAATCAATTACTTTTAGATCCAGAAATTGATATTATTTATATTTGTAGTCCAACTGATACGCACTAT
CTTTATTCAATTCAAGCACTCAAAGCTAATAAACACGTTTTTTGTGAAAAACCAGTGGCTTTTGATCTTGAAAAAATTCT
TGAAGTTAAAAAAGTTGTAAAAGAAACTAAAAAATATTTCACCGTTGGACATAATCGAAGATTTGATCATAATTTTTTAG
CACTAAAAGATCAAATTGAAAAAAATACAATCGGTGAAATTCTCCAGTTAAGAATTACTTCCCGCGATCCAGGACTTCCT
CCATATGAATATATCAAAAAATCCGGTGGAATTTTTCTTGATATGATGATTCATGACTTTGACATGGCACTTTTTCTAAC
TAATAATAAGGTAGTTGAATCTGTCTATGCAACAGGTTCAGCTTTAATTGATAAAAAAATTAGCGAATTAGATGATATTG
ATACCGCCGTTGTTGTTCTAAATTTCAAAGATGGTTCAATGGCAACAATCGAAAACTGTCGTCAGACAAGTTATGGATAT
GACCAAAGAGTTGAAATCCACGGAACAAAAGCGAGTATCAAAATTGAAAATGATACAAATTCAACCTTGATAATTTCTTC
AGATCACGGAATAATTAAGGAAAAACCGCTTTATTTTTTCCTTGAAAGATATCAAAATGCCTACATTCAAGAAAATAAAG
ACTTTTTTGAGGCAATTTCTTCTAATAAGGAGCCAAAAGTAACAATTGATGATGGTTATAAAGCGGTTTTACTTGCAAAA
GCTGCAAAAATATCTCTAAAAGAAAAACGATTAGTGAAAATAAGTGAGTTAGAGGAATAA

Upstream 100 bases:

>100_bases
ATTATTCGCCATTTAGAAAATAATCCTTGAATTGATCGGATCGAAGCTCAAGAACATCTCTGACTAAATCAAGAAAATCC
AAATTATTGAAAGGAAAAAG

Downstream 100 bases:

>100_bases
TGGCAAAGACAATTCGACTAACAACCGCACAGGCAATTATTAAATTTATTGATAATGTTTATCTAAAAATTGATGCAAAA
ACAACCAAATTTGTCTATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKFKVGIIGGGRIGYVHTHAINKFVDDAKVIAIADAYLDSQNQEKFRKLGVKSFYSDYNQLLLDPEIDIIYICSPTDTHY
LYSIQALKANKHVFCEKPVAFDLEKILEVKKVVKETKKYFTVGHNRRFDHNFLALKDQIEKNTIGEILQLRITSRDPGLP
PYEYIKKSGGIFLDMMIHDFDMALFLTNNKVVESVYATGSALIDKKISELDDIDTAVVVLNFKDGSMATIENCRQTSYGY
DQRVEIHGTKASIKIENDTNSTLIISSDHGIIKEKPLYFFLERYQNAYIQENKDFFEAISSNKEPKVTIDDGYKAVLLAK
AAKISLKEKRLVKISELEE

Sequences:

>Translated_339_residues
MKFKVGIIGGGRIGYVHTHAINKFVDDAKVIAIADAYLDSQNQEKFRKLGVKSFYSDYNQLLLDPEIDIIYICSPTDTHY
LYSIQALKANKHVFCEKPVAFDLEKILEVKKVVKETKKYFTVGHNRRFDHNFLALKDQIEKNTIGEILQLRITSRDPGLP
PYEYIKKSGGIFLDMMIHDFDMALFLTNNKVVESVYATGSALIDKKISELDDIDTAVVVLNFKDGSMATIENCRQTSYGY
DQRVEIHGTKASIKIENDTNSTLIISSDHGIIKEKPLYFFLERYQNAYIQENKDFFEAISSNKEPKVTIDDGYKAVLLAK
AAKISLKEKRLVKISELEE
>Mature_339_residues
MKFKVGIIGGGRIGYVHTHAINKFVDDAKVIAIADAYLDSQNQEKFRKLGVKSFYSDYNQLLLDPEIDIIYICSPTDTHY
LYSIQALKANKHVFCEKPVAFDLEKILEVKKVVKETKKYFTVGHNRRFDHNFLALKDQIEKNTIGEILQLRITSRDPGLP
PYEYIKKSGGIFLDMMIHDFDMALFLTNNKVVESVYATGSALIDKKISELDDIDTAVVVLNFKDGSMATIENCRQTSYGY
DQRVEIHGTKASIKIENDTNSTLIISSDHGIIKEKPLYFFLERYQNAYIQENKDFFEAISSNKEPKVTIDDGYKAVLLAK
AAKISLKEKRLVKISELEE

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=237, Percent_Identity=28.6919831223629, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081947, Length=151, Percent_Identity=32.4503311258278, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082405, Length=378, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789848, Length=141, Percent_Identity=31.2056737588652, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581117, Length=258, Percent_Identity=23.6434108527132, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38677; Mature: 38677

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKVGIIGGGRIGYVHTHAINKFVDDAKVIAIADAYLDSQNQEKFRKLGVKSFYSDYNQ
CEEEEEEEECCEEEEEEHHHHHHHHCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
LLLDPEIDIIYICSPTDTHYLYSIQALKANKHVFCEKPVAFDLEKILEVKKVVKETKKYF
EEECCCCCEEEEECCCCCEEEEEEEEEECCCCEEECCCCHHCHHHHHHHHHHHHHHHHHE
TVGHNRRFDHNFLALKDQIEKNTIGEILQLRITSRDPGLPPYEYIKKSGGIFLDMMIHDF
ECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHCCCCEEEEEEEECC
DMALFLTNNKVVESVYATGSALIDKKISELDDIDTAVVVLNFKDGSMATIENCRQTSYGY
EEEEEEECCHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCC
DQRVEIHGTKASIKIENDTNSTLIISSDHGIIKEKPLYFFLERYQNAYIQENKDFFEAIS
CCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
SNKEPKVTIDDGYKAVLLAKAAKISLKEKRLVKISELEE
CCCCCEEEECCCCEEEEEEHHHHCCCCHHHEEEECCCCC
>Mature Secondary Structure
MKFKVGIIGGGRIGYVHTHAINKFVDDAKVIAIADAYLDSQNQEKFRKLGVKSFYSDYNQ
CEEEEEEEECCEEEEEEHHHHHHHHCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
LLLDPEIDIIYICSPTDTHYLYSIQALKANKHVFCEKPVAFDLEKILEVKKVVKETKKYF
EEECCCCCEEEEECCCCCEEEEEEEEEECCCCEEECCCCHHCHHHHHHHHHHHHHHHHHE
TVGHNRRFDHNFLALKDQIEKNTIGEILQLRITSRDPGLPPYEYIKKSGGIFLDMMIHDF
ECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHCCCCEEEEEEEECC
DMALFLTNNKVVESVYATGSALIDKKISELDDIDTAVVVLNFKDGSMATIENCRQTSYGY
EEEEEEECCHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCC
DQRVEIHGTKASIKIENDTNSTLIISSDHGIIKEKPLYFFLERYQNAYIQENKDFFEAIS
CCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
SNKEPKVTIDDGYKAVLLAKAAKISLKEKRLVKISELEE
CCCCCEEEECCCCEEEEEEHHHHCCCCHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]