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The map label for this gene is iolE [H]

Identifier: 54020366

GI number: 54020366

Start: 177311

End: 178213

Strand: Reverse

Name: iolE [H]

Synonym: mhp148

Alternate gene names: 54020366

Gene position: 178213-177311 (Counterclockwise)

Preceding gene: 54020367

Following gene: 54020365

Centisome position: 19.96

GC content: 31.67

Gene sequence:

>903_bases
ATGAATAAAATCTGAAAACTAAAAAATGTTAAAGTCGGTGTTGCTCCAATTTTATGAACAAATGATGATATGCCTGAATT
AGGAGGAGATATTTCCTTTGATCGTGCAATTTCAGAGATGGCACAAGCCGGTTATCAGGGCACCGAAATTGGCAATAAAT
TCCCAAAAGATGCAAAAATTTTACTCAGGGAACTAAAAAAATATAATCTTGAAATCGCATCTGCTTGATTTAGTGGATAT
ATTATATCAGATTTTGAGAAAAATTTTCAAGATTTTCAAAAACATTGCTTATTTTTAAAGGCCTTAGGAGCGAAAGTTGT
TGTTTTTAGCGAGCAAACTTATTCAATTCAAGGTCAAAATAAACCACTTTTTAAAGATAAACCTTATTTTACAAATCAAG
AATTTGAAAATCTTGCCCAGGGTCTTAATAAATTTGGTAAATGATCAAAACAGCACGGAATTGAGCTAGTTTATCATCAT
CATATGGGAACAGGAATTCAGTCTCTTAAAGAAACAGAAAAAATTCTTGAACTAACTGATCCTGAATTTGTCAGTCTGAT
TTTTGATACTGGTCATTTTGCTCATGCGGGCGAAGATATTGTTTTTTGTCTTAAAAGATTAATCTCCCGGATAAGACATA
TTCATCTAAAAGATATAAGAAAAGAAAAAATTAATGAATTAAAAGCGAAAAATTTAAGTTTTCTTGAAGGGGTAAAACAA
GGAATTTTCACTGTTCCAGGGGATGGTGATATTCAAAATTATCCTTTATTTTTCGAGCTTTTAGCCAAAAATAACTATCA
AGGCTGGCTAATTGTTGAAGCCGAACAAGACCCGCGAAAAGCAAATCCACTTGAATATGCCAAAAAAGCAATGGATTATC
TAAGATCACTAATTTCATGATAA

Upstream 100 bases:

>100_bases
TCTGACAAACCGGCCTTTCACTTGTATCTAAAAATAAAGAAATTGAAGAACTTGCCAAAGAAAATGAAAAAATCCTTAAG
GAGAATAACAATTTTAACTA

Downstream 100 bases:

>100_bases
GGAGGTAAATATTGAATTCTATCCAAAAACATCCATTATTTTTTAAACTTGAGAAAATCAATTTAAGTTTTGGCCCTGTT
AAAGTTCTAAAAAATATGAA

Product: myo-inositol catabolism protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNKIWKLKNVKVGVAPILWTNDDMPELGGDISFDRAISEMAQAGYQGTEIGNKFPKDAKILLRELKKYNLEIASAWFSGY
IISDFEKNFQDFQKHCLFLKALGAKVVVFSEQTYSIQGQNKPLFKDKPYFTNQEFENLAQGLNKFGKWSKQHGIELVYHH
HMGTGIQSLKETEKILELTDPEFVSLIFDTGHFAHAGEDIVFCLKRLISRIRHIHLKDIRKEKINELKAKNLSFLEGVKQ
GIFTVPGDGDIQNYPLFFELLAKNNYQGWLIVEAEQDPRKANPLEYAKKAMDYLRSLISW

Sequences:

>Translated_300_residues
MNKI*KLKNVKVGVAPIL*TNDDMPELGGDISFDRAISEMAQAGYQGTEIGNKFPKDAKILLRELKKYNLEIASA*FSGY
IISDFEKNFQDFQKHCLFLKALGAKVVVFSEQTYSIQGQNKPLFKDKPYFTNQEFENLAQGLNKFGK*SKQHGIELVYHH
HMGTGIQSLKETEKILELTDPEFVSLIFDTGHFAHAGEDIVFCLKRLISRIRHIHLKDIRKEKINELKAKNLSFLEGVKQ
GIFTVPGDGDIQNYPLFFELLAKNNYQGWLIVEAEQDPRKANPLEYAKKAMDYLRSLIS*
>Mature_300_residues
MNKI*KLKNVKVGVAPIL*TNDDMPELGGDISFDRAISEMAQAGYQGTEIGNKFPKDAKILLRELKKYNLEIASA*FSGY
IISDFEKNFQDFQKHCLFLKALGAKVVVFSEQTYSIQGQNKPLFKDKPYFTNQEFENLAQGLNKFGK*SKQHGIELVYHH
HMGTGIQSLKETEKILELTDPEFVSLIFDTGHFAHAGEDIVFCLKRLISRIRHIHLKDIRKEKINELKAKNLSFLEGVKQ
GIFTVPGDGDIQNYPLFFELLAKNNYQGWLIVEAEQDPRKANPLEYAKKAMDYLRSLIS*

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33558; Mature: 33558

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKLKNVKVGVAPILTNDDMPELGGDISFDRAISEMAQAGYQGTEIGNKFPKDAKILL
CCCEEEECEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHCCCCCHHHHHHH
RELKKYNLEIASAFSGYIISDFEKNFQDFQKHCLFLKALGAKVVVFSEQTYSIQGQNKPL
HHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCC
FKDKPYFTNQEFENLAQGLNKFGKSKQHGIELVYHHHMGTGIQSLKETEKILELTDPEFV
CCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEEEECHHCHHHHHHHHHHHHHHCCCCHHH
SLIFDTGHFAHAGEDIVFCLKRLISRIRHIHLKDIRKEKINELKAKNLSFLEGVKQGIFT
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEE
VPGDGDIQNYPLFFELLAKNNYQGWLIVEAEQDPRKANPLEYAKKAMDYLRSLIS
CCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNKIKLKNVKVGVAPILTNDDMPELGGDISFDRAISEMAQAGYQGTEIGNKFPKDAKILL
CCCEEEECEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHCCCCCHHHHHHH
RELKKYNLEIASAFSGYIISDFEKNFQDFQKHCLFLKALGAKVVVFSEQTYSIQGQNKPL
HHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCC
FKDKPYFTNQEFENLAQGLNKFGKSKQHGIELVYHHHMGTGIQSLKETEKILELTDPEFV
CCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEEEECHHCHHHHHHHHHHHHHHCCCCHHH
SLIFDTGHFAHAGEDIVFCLKRLISRIRHIHLKDIRKEKINELKAKNLSFLEGVKQGIFT
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEE
VPGDGDIQNYPLFFELLAKNNYQGWLIVEAEQDPRKANPLEYAKKAMDYLRSLIS
CCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA