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The map label for this gene is nagA

Identifier: 54020252

GI number: 54020252

Start: 738609

End: 739763

Strand: Direct

Name: nagA

Synonym: mhp588

Alternate gene names: 54020252

Gene position: 738609-739763 (Clockwise)

Preceding gene: 54020251

Following gene: 54020253

Centisome position: 82.73

GC content: 27.45

Gene sequence:

>1155_bases
ATGATTTATAAAAATCTTAGAATTGTTAGTCATTCTGATGAATTTATAGGTTGAATTGAACTTGATAAAAACGGAATTAT
TGTTAATTTATGTAGAGGAAATACAGAATCTTCAGGAATTGACTGCAAAAACCACGTTTTATTACCGGCTTTTATTGATT
CGCACACCCACGGCGGCTATGGATTTTCATTTGATGACTTTTCAGATAGTTGCTGAGAACAAAATTTTTTAGATTATAAG
GAAAAACTACATAAATTTGAAGGTGTAGCAGCAATTTTTGGAACAACTATTACCCAGCAATGAGAAAAAATTAAGGTAAA
TAGTGAATTTTTTTTATTTTTGCTTAATAAATATCCTAATTTTTTACTAAATTGATATTTAGAAGGTCCGTTTATTTCTG
AGGAAAAAAAGGGGGCACACAATCAAGGTTTAATAATTAAACCGAAAAGAGAACATTTTAAGTTTTTGGCAGAAAAATTT
AACAAAAAAATTACAGTAGTAGTTGCCCCTGAAAAAACTTCTGCAAAATTAATTGATTCTTTTTATAAAACAATTAATTT
TGCAATTGGGCATTCGAATTCTTTTGACTTCAAAAGGAATCATAATTTAAAAAAGTACTATAAATTTACACACTTTTTTA
ATGGATGTTCAAATTTTGACCACCGAAAACAATCACTTGTCAACCTTATTTTTGAATCAAAATTACCTAAAAATTTTCTT
GTTGAGTTAATCACTGACAGCCTTCATATTAAAAATTCAACCCTCAAATTTACAATTAAAAATATTAAAAAAGAAAATTG
GGTTGCAGTCTCAGACTCGCTTGCACAAAAAGGACTTGATAATGGATTTTATAAATTAGGAGAACTAAAAATTGAGAAGA
AAGGTGATTTATTCTATCTAAAAAATTCAAAACAAATTGCCGGAAGTGGGATGTCATATTTAAAAATTCTTAAGAATTTA
AAGTTAAATTTGAAACTATCTTGACAGGAAATAGTTTTTTGTTCCTCTTATAATGTGGCAAATTCATTGGGAATTCTAGA
TTTTTTTGGGTCAATTAAGATAGGACAAAAAGCAAATTTTGTAATTTTAGATGATAAATTTGAACTAAAAATGTCAATCA
TTTTTGGCCAAATTTACCGCGAATTTGCAAAATAG

Upstream 100 bases:

>100_bases
TTATTATATAAAAAGAACAAAATTCAAAAATTACTAAAAAATAACTTAAAATATGGTATAATTATACCTACAAAGTTATA
GCTAACTTAAATATTTAAAA

Downstream 100 bases:

>100_bases
TCTATGAATTTAAAGCTTTTTTAAACCAGAGAAGAAAAATAAAATGTTAGATTCTTATGCTATTTTAAGATAAGAAAGAA
TTTTTTCTGTCATCTTTTCA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MIYKNLRIVSHSDEFIGWIELDKNGIIVNLCRGNTESSGIDCKNHVLLPAFIDSHTHGGYGFSFDDFSDSCWEQNFLDYK
EKLHKFEGVAAIFGTTITQQWEKIKVNSEFFLFLLNKYPNFLLNWYLEGPFISEEKKGAHNQGLIIKPKREHFKFLAEKF
NKKITVVVAPEKTSAKLIDSFYKTINFAIGHSNSFDFKRNHNLKKYYKFTHFFNGCSNFDHRKQSLVNLIFESKLPKNFL
VELITDSLHIKNSTLKFTIKNIKKENWVAVSDSLAQKGLDNGFYKLGELKIEKKGDLFYLKNSKQIAGSGMSYLKILKNL
KLNLKLSWQEIVFCSSYNVANSLGILDFFGSIKIGQKANFVILDDKFELKMSIIFGQIYREFAK

Sequences:

>Translated_384_residues
MIYKNLRIVSHSDEFIG*IELDKNGIIVNLCRGNTESSGIDCKNHVLLPAFIDSHTHGGYGFSFDDFSDSC*EQNFLDYK
EKLHKFEGVAAIFGTTITQQ*EKIKVNSEFFLFLLNKYPNFLLN*YLEGPFISEEKKGAHNQGLIIKPKREHFKFLAEKF
NKKITVVVAPEKTSAKLIDSFYKTINFAIGHSNSFDFKRNHNLKKYYKFTHFFNGCSNFDHRKQSLVNLIFESKLPKNFL
VELITDSLHIKNSTLKFTIKNIKKENWVAVSDSLAQKGLDNGFYKLGELKIEKKGDLFYLKNSKQIAGSGMSYLKILKNL
KLNLKLS*QEIVFCSSYNVANSLGILDFFGSIKIGQKANFVILDDKFELKMSIIFGQIYREFAK
>Mature_384_residues
MIYKNLRIVSHSDEFIG*IELDKNGIIVNLCRGNTESSGIDCKNHVLLPAFIDSHTHGGYGFSFDDFSDSC*EQNFLDYK
EKLHKFEGVAAIFGTTITQQ*EKIKVNSEFFLFLLNKYPNFLLN*YLEGPFISEEKKGAHNQGLIIKPKREHFKFLAEKF
NKKITVVVAPEKTSAKLIDSFYKTINFAIGHSNSFDFKRNHNLKKYYKFTHFFNGCSNFDHRKQSLVNLIFESKLPKNFL
VELITDSLHIKNSTLKFTIKNIKKENWVAVSDSLAQKGLDNGFYKLGELKIEKKGDLFYLKNSKQIAGSGMSYLKILKNL
KLNLKLS*QEIVFCSSYNVANSLGILDFFGSIKIGQKANFVILDDKFELKMSIIFGQIYREFAK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Escherichia coli, GI1786892, Length=345, Percent_Identity=24.0579710144928, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17553768, Length=352, Percent_Identity=28.6931818181818, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19920392, Length=356, Percent_Identity=25, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281361140, Length=369, Percent_Identity=24.6612466124661, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 43429; Mature: 43429

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYKNLRIVSHSDEFIGIELDKNGIIVNLCRGNTESSGIDCKNHVLLPAFIDSHTHGGYG
CCEECEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCC
FSFDDFSDSCEQNFLDYKEKLHKFEGVAAIFGTTITQQEKIKVNSEFFLFLLNKYPNFLL
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCEEEEEHHHCHHHHH
NYLEGPFISEEKKGAHNQGLIIKPKREHFKFLAEKFNKKITVVVAPEKTSAKLIDSFYKT
HHHCCCCCCCHHCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
INFAIGHSNSFDFKRNHNLKKYYKFTHFFNGCSNFDHRKQSLVNLIFESKLPKNFLVELI
HEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TDSLHIKNSTLKFTIKNIKKENWVAVSDSLAQKGLDNGFYKLGELKIEKKGDLFYLKNSK
HCCCEECCCEEEEEEECCCCCCEEEECHHHHHCCCCCCCEEECEEEEECCCCEEEEECCC
QIAGSGMSYLKILKNLKLNLKLSQEIVFCSSYNVANSLGILDFFGSIKIGQKANFVILDD
EECCCCHHHHHHHHCCEEEEEEECEEEEEECCCCHHHCCHHHHHCCEEECCCCCEEEECC
KFELKMSIIFGQIYREFAK
CCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MIYKNLRIVSHSDEFIGIELDKNGIIVNLCRGNTESSGIDCKNHVLLPAFIDSHTHGGYG
CCEECEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCC
FSFDDFSDSCEQNFLDYKEKLHKFEGVAAIFGTTITQQEKIKVNSEFFLFLLNKYPNFLL
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCEEEEEHHHCHHHHH
NYLEGPFISEEKKGAHNQGLIIKPKREHFKFLAEKFNKKITVVVAPEKTSAKLIDSFYKT
HHHCCCCCCCHHCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
INFAIGHSNSFDFKRNHNLKKYYKFTHFFNGCSNFDHRKQSLVNLIFESKLPKNFLVELI
HEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TDSLHIKNSTLKFTIKNIKKENWVAVSDSLAQKGLDNGFYKLGELKIEKKGDLFYLKNSK
HCCCEECCCEEEEEEECCCCCCEEEECHHHHHCCCCCCCEEECEEEEECCCCEEEEECCC
QIAGSGMSYLKILKNLKLNLKLSQEIVFCSSYNVANSLGILDFFGSIKIGQKANFVILDD
EECCCCHHHHHHHHCCEEEEEEECEEEEEECCCCHHHCCHHHHHCCEEECCCCCEEEECC
KFELKMSIIFGQIYREFAK
CCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]