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The map label for this gene is infC

Identifier: 54020112

GI number: 54020112

Start: 282448

End: 283101

Strand: Direct

Name: infC

Synonym: mhp256

Alternate gene names: 54020112

Gene position: 282448-283101 (Clockwise)

Preceding gene: 54020111

Following gene: 54020113

Centisome position: 31.64

GC content: 29.2

Gene sequence:

>654_bases
TTGAATCACAGACCCCCTTTCCAGAAAAAACCATTACAAGACCACCAAATTAACGAAAATATACTTTTTCCCAACATTTT
TTTAGTTGGAACTGATAATGAAAAAATTGGGAAAATGGCAACAAAAGAAGCAATTGAGTTAGCTAAATCCAAAGGTCTTG
ATTTAGTTTTAATTTCGATTAAGGAAGTTAAAACTAAAGATAATCAAATTCAAAAAGTTCCAATTGCAAAAATTCTTGAC
TATGGTAAATTTCGTTATGATATAAAAAAGAAAAAAAAAGAAGAAAAAGAAAAGCAATCTTTTACTAATAATCGTGAAAT
TCGCGTTAGTTTTAATATAAATTTCCAGGATATATTAGTTAAATCGAAAAAAGCTCGTGAATTTATTCTTGATGGTGATC
GTGTTAAAATTGCCCTTCGTTTCCGCGGTCGTGAAATTACTAGGGTTGATCAAGGCAGAAAAACACTTGATATCTTTTAT
GATCAGTTAAAATATATTGCTAAAAAAAGTAAAGAAATTTCACAAAATGGGAACTTTTTAGTTATGCATCTTGAACGTGA
TCGCAAAAAACTCCCAAAATTCACTTCAGCAAAACAACTAAAAGAATTACTCGAATACGAAAAACAAAAAAAAGAGGAAG
AAGAGAATGTCTAA

Upstream 100 bases:

>100_bases
TATTATTTTTTTGTCCAAAATTAAAATTAAATTCGTTTTTTAGTAAATTTTTTTAAAAAAAAATTTACTAAACGATCTAA
AATGGAGTAAAACTTAAATT

Downstream 100 bases:

>100_bases
AATCAAATTTAAAACAAAATCAGCATTAAAAAAAAGGATAAAAGTAACGGGAACAGGAAAAGTTAAACATGGCCATGCTT
ATCGTTCACATCTAGCTCAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKMATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKILD
YGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFY
DQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFTSAKQLKELLEYEKQKKEEEENV

Sequences:

>Translated_217_residues
MNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKMATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKILD
YGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFY
DQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFTSAKQLKELLEYEKQKKEEEENV
>Mature_217_residues
MNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKMATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKILD
YGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFY
DQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFTSAKQLKELLEYEKQKKEEEENV

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=153, Percent_Identity=34.640522875817, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25694; Mature: 25694

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKMATKEAIELAKSKGLDLVLISI
CCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEE
KEVKTKDNQIQKVPIAKILDYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILV
EHHHCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
KSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFYDQLKYIAKKSKEISQNGNFL
HHHHHHHHEECCCEEEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
VMHLERDRKKLPKFTSAKQLKELLEYEKQKKEEEENV
EEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKMATKEAIELAKSKGLDLVLISI
CCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEE
KEVKTKDNQIQKVPIAKILDYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILV
EHHHCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
KSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFYDQLKYIAKKSKEISQNGNFL
HHHHHHHHEECCCEEEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
VMHLERDRKKLPKFTSAKQLKELLEYEKQKKEEEENV
EEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486291 [H]