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The map label for this gene is rpe

Identifier: 54020106

GI number: 54020106

Start: 257358

End: 258008

Strand: Direct

Name: rpe

Synonym: mhp231

Alternate gene names: 54020106

Gene position: 257358-258008 (Clockwise)

Preceding gene: 54020105

Following gene: 54020107

Centisome position: 28.83

GC content: 26.11

Gene sequence:

>651_bases
ATGAAAAGAAAAATTATTAGCCCCTCGCTTTTGAATATAAAAAAATCTAGTCGGCTAAAATCAACAAGAATTTTTTTGAA
TCTTGGCATAAAATGATTTCACTTTGATTTTATGGATGGTATATTTGTTAAGAATGTAGCAATATCTATTCCAGAAATCA
AAAATATTATTAAAAAATCAAAAGAATTTATCTCTGATGTTCATTTAATGTCTGTTAATCCCGAAGAGCAAATTAAGCAA
TTACTAGGGTATGTGAATTTTGCAACAATTCATTTTGAAAGTAGAAATTATGCCCAAATTAAAGAGATAATATCAAAATA
TTCGCGAAAAATTAAAATAGGAATAGCAATAAAACCTGAGACAAAAATAGAACAAATTTATGATTTATTACCCGAAATTC
AGCTAGTTCTAATAATGTCAGTTGAACCTGGCAAAGGCGGTCAGGCTTTTATCGAAAATACTTATAAAAAAATAGAAGAA
TTATCCAAAATAATTCAAGAAAATAATTATAAAATTATCATTCAAGTTGATGGTGGCATTAAGGATTTTAATTCAAAAAA
GGTTTTTGATTCTGGGGCTGACGTTATTGTAGTCGGAACTTTTTTAGCTGAAAAACCAACAAAATTAAAAATTAAAAAAT
TAATTAATTAA

Upstream 100 bases:

>100_bases
TTTCAGGAGAAAACTGATCAATGCGGCATTAAAAGGGCGCTAAAAGATGGAAAAATACCAGAAAATCGTTATAAAAATTA
TCTTTATTTTTTAGGAAAAT

Downstream 100 bases:

>100_bases
TTAATTAATTTTTTAATTAATAAAAAAACCCAATTTATAAATTTTTCCATAAATTGGGTTTGTAAAACTGTTATTTTTAA
AATTTATAAAAATTTAACTC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKRKIISPSLLNIKKSSRLKSTRIFLNLGIKWFHFDFMDGIFVKNVAISIPEIKNIIKKSKEFISDVHLMSVNPEEQIKQ
LLGYVNFATIHFESRNYAQIKEIISKYSRKIKIGIAIKPETKIEQIYDLLPEIQLVLIMSVEPGKGGQAFIENTYKKIEE
LSKIIQENNYKIIIQVDGGIKDFNSKKVFDSGADVIVVGTFLAEKPTKLKIKKLIN

Sequences:

>Translated_216_residues
MKRKIISPSLLNIKKSSRLKSTRIFLNLGIK*FHFDFMDGIFVKNVAISIPEIKNIIKKSKEFISDVHLMSVNPEEQIKQ
LLGYVNFATIHFESRNYAQIKEIISKYSRKIKIGIAIKPETKIEQIYDLLPEIQLVLIMSVEPGKGGQAFIENTYKKIEE
LSKIIQENNYKIIIQVDGGIKDFNSKKVFDSGADVIVVGTFLAEKPTKLKIKKLIN
>Mature_216_residues
MKRKIISPSLLNIKKSSRLKSTRIFLNLGIK*FHFDFMDGIFVKNVAISIPEIKNIIKKSKEFISDVHLMSVNPEEQIKQ
LLGYVNFATIHFESRNYAQIKEIISKYSRKIKIGIAIKPETKIEQIYDLLPEIQLVLIMSVEPGKGGQAFIENTYKKIEE
LSKIIQENNYKIIIQVDGGIKDFNSKKVFDSGADVIVVGTFLAEKPTKLKIKKLIN

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=199, Percent_Identity=32.1608040201005, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI219879828, Length=207, Percent_Identity=29.951690821256, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1790523, Length=195, Percent_Identity=31.2820512820513, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789788, Length=212, Percent_Identity=29.2452830188679, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=203, Percent_Identity=33.9901477832512, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322341, Length=224, Percent_Identity=33.4821428571429, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24586301, Length=201, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24567; Mature: 24567

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIISPSLLNIKKSSRLKSTRIFLNLGIKFHFDFMDGIFVKNVAISIPEIKNIIKKSK
CCCCCCCCHHHCCHHHCCCCCEEEEEEECEEEEEEHHCCEEEHHHEEECHHHHHHHHHHH
EFISDVHLMSVNPEEQIKQLLGYVNFATIHFESRNYAQIKEIISKYSRKIKIGIAIKPET
HHHHHEEEEECCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCH
KIEQIYDLLPEIQLVLIMSVEPGKGGQAFIENTYKKIEELSKIIQENNYKIIIQVDGGIK
HHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
DFNSKKVFDSGADVIVVGTFLAEKPTKLKIKKLIN
CCCCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MKRKIISPSLLNIKKSSRLKSTRIFLNLGIKFHFDFMDGIFVKNVAISIPEIKNIIKKSK
CCCCCCCCHHHCCHHHCCCCCEEEEEEECEEEEEEHHCCEEEHHHEEECHHHHHHHHHHH
EFISDVHLMSVNPEEQIKQLLGYVNFATIHFESRNYAQIKEIISKYSRKIKIGIAIKPET
HHHHHEEEEECCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCH
KIEQIYDLLPEIQLVLIMSVEPGKGGQAFIENTYKKIEELSKIIQENNYKIIIQVDGGIK
HHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
DFNSKKVFDSGADVIVVGTFLAEKPTKLKIKKLIN
CCCCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]