Click here to switch to the map view.

The map label for this gene is ftsW

Identifier: 52842821

GI number: 52842821

Start: 2951164

End: 2952348

Strand: Reverse

Name: ftsW

Synonym: lpg2615

Alternate gene names: 52842821

Gene position: 2952348-2951164 (Counterclockwise)

Preceding gene: 52842822

Following gene: 52842820

Centisome position: 86.89

GC content: 40.34

Gene sequence:

>1185_bases
GTGAACACGATGCGACCGAGACATTTAAATCAAAGAGGCAAACCCGTTAGCAGGCCGATATCACTTTATGATAAATGGCT
GATAGGGGCAGTTTTTGGTTTGCTGATAATTGGTTTGATGATGGTGGCATCAAGCTCGGTTATGATTTCAACAAAGTACT
TTCATCAACCTTTTCATTTTCTTATTCGCCAGGCTTGTTATTTATTTGTGGGACTCTTGCTGGCCTTAATTGTGGTGCGT
ACAGACAGCAGTTTCTGGGAAAAAATAAGCATGCCCATGATGATTGGTTGCGTGTTTTTATTGCTCATTGTTTTAATCCC
GGGTATTGGTAAATCAGTGAATGGCAGTCGACGTTGGTTAGCTTTAGGTCCGATTGGTGTGCAAGTCTCAGAATTAACGA
AACTTGCAATGATATTCTATCTTTCCGGGTATTTGGTTCGCCAGCAAGAGGCGGTTTGTGAAAGCATTTTTGGATTCATT
AAGCCCATGGCAATACTGGCTGTTGTTTCAGTTTTATTACTGCTCGAACCAGATTTTGGAGCGACAGTTGTCATTTCTGG
TACAGTAATGGCTATGTTATTTTTAGCTGGAGTTAAATTAAGATACTATTTTGGTTTAATGCTGGTTGTAGTGACAGCAC
TTGCTCTGTTGGCGGTATCTTCCCCCTATAGGGTTGCTCGCTTAACAGCCTTTTTGGATCCGTGGGCAGATCAATACAAT
AGTGGTTATCAATTGACTCAGTCATTGATTGCTTTCGGACGAGGTGGATGGTTTGGTACCGGATTAGGTGAAAGCATACA
GAAATTACTCTATTTACCTGAGGCACATACTGATTTTTTATTTGCTGTGATTGCTGAAGAATTAGGGTTATTTGGAATTT
TAGTTGTCATCACATTGTATAGTATACTGGTTATTAGAGGATTAAACATAGGATATACCGCCTATACTCAAGAAAGGCAT
TTTGCATCCTATACAGCCTATGGTTTGACTATTTGGTTAGCTTTACAGGCTTCTATTAATATGGGTGTTAATGCCGGACT
GTTACCAACCAAAGGGCTAACTCTGCCTTTACTCAGTTATGGTGGGGCCAGTATGGTAATTAATTGTATCGTTATTGCAC
TATTATTGCGCATAGATCATGAAAATCGTTGGCAGTCTCTTGGGTTGAGACCGCTAACGGCTTAA

Upstream 100 bases:

>100_bases
CTGGTGATGTCGTTTTATTATCTCCAGCTTGTGCCAGTTTGGATATGTTCCGTGATTTTAATCATAGGGGCGATGTGTTT
ACATCTTCAGTGCGCGGATT

Downstream 100 bases:

>100_bases
GGGGGAATATTGAATAACTCAGAGCAATTTTTATCTCCGCGCATGGGGCGTGTAGAGCAAATTCATTTTGTTGGCATTGG
TGGTGCTGGTATGTGTGGTA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVR
TDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFI
KPMAILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYN
SGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERH
FASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA

Sequences:

>Translated_394_residues
MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVR
TDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFI
KPMAILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYN
SGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERH
FASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA
>Mature_394_residues
MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVR
TDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFI
KPMAILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYN
SGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERH
FASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=46.4088397790055, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=32.1321321321321, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43432; Mature: 43432

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
LIRQACYLFVGLLLALIVVRTDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPMAILAVVSVLLLLEPDFG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYN
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SILVIRGLNIGYTAYTQERHFASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSY
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHC
GGASMVINCIVIALLLRIDHENRWQSLGLRPLTA
CCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
LIRQACYLFVGLLLALIVVRTDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPMAILAVVSVLLLLEPDFG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYN
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SILVIRGLNIGYTAYTQERHFASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSY
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHC
GGASMVINCIVIALLLRIDHENRWQSLGLRPLTA
CCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]