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The map label for this gene is hypC

Identifier: 52842681

GI number: 52842681

Start: 2787624

End: 2787851

Strand: Reverse

Name: hypC

Synonym: lpg2473

Alternate gene names: 52842681

Gene position: 2787851-2787624 (Counterclockwise)

Preceding gene: 52842682

Following gene: 52842680

Centisome position: 82.05

GC content: 41.67

Gene sequence:

>228_bases
ATGTGCTTAGCGTTGCCAGCGCAAATTGATCAGGTTTTGGAAGATAACAAGGCAATCGTTAATTTGGGTGGGATCACCAA
GGAAATTTCCACTGTTCTTTTGGAGCAGGTTTCTGAAGGAGAGTACGTCATTATTCATGCAGGATTCGCCTTAACAAAAC
TGGATGAAAGAGAGGCAAACAAAACATTGAGTTTGTTTGCCCATATGCTAAAGGATGGCTTGAAGTGA

Upstream 100 bases:

>100_bases
AGGTATTAAACCCCTGTTGCCCAAATTGCTTCCACCAAATGATGGTGGAATTGCGCTAGGTCAAGCATGGATTGTTGGAA
TAAAAGAATAAGGGTGGCTT

Downstream 100 bases:

>100_bases
AATACATAGAAGAGTTTCGTAACGGTGCTTACGCACAAGCCATTATCAATGAAATTATCGCAACAGCAGAGCCGCAAAGA
CATTATCAGTTTATGGAGTT

Product: hydrogenase expression/formation protein HypC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MCLALPAQIDQVLEDNKAIVNLGGITKEISTVLLEQVSEGEYVIIHAGFALTKLDEREANKTLSLFAHMLKDGLK

Sequences:

>Translated_75_residues
MCLALPAQIDQVLEDNKAIVNLGGITKEISTVLLEQVSEGEYVIIHAGFALTKLDEREANKTLSLFAHMLKDGLK
>Mature_75_residues
MCLALPAQIDQVLEDNKAIVNLGGITKEISTVLLEQVSEGEYVIIHAGFALTKLDEREANKTLSLFAHMLKDGLK

Specific function: Is Required For The Formation Of All Three Hydrogenase Isoenzymes. May Bind To The Precursor Form Of The Large Subunit Of Dehydrogenases To Keep Them In A Conformation Accessible For Metal Incorporation. [C]

COG id: COG0298

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupF/hypC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019812
- InterPro:   IPR001109 [H]

Pfam domain/function: PF01455 HupF_HypC [H]

EC number: NA

Molecular weight: Translated: 8210; Mature: 8210

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01097 HUPF_HYPC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLALPAQIDQVLEDNKAIVNLGGITKEISTVLLEQVSEGEYVIIHAGFALTKLDEREAN
CCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHHH
KTLSLFAHMLKDGLK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MCLALPAQIDQVLEDNKAIVNLGGITKEISTVLLEQVSEGEYVIIHAGFALTKLDEREAN
CCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHHH
KTLSLFAHMLKDGLK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]