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The map label for this gene is bglH [H]

Identifier: 52787891

GI number: 52787891

Start: 4047540

End: 4048949

Strand: Reverse

Name: bglH [H]

Synonym: BLi04214

Alternate gene names: 52787891

Gene position: 4048949-4047540 (Counterclockwise)

Preceding gene: 52787892

Following gene: 52787890

Centisome position: 95.89

GC content: 47.87

Gene sequence:

>1410_bases
ATGACTGAACAAACGAAAAAGTTTCCTGAAGGTTTTTTATGGGGCGGAGCGGTTGCCGCAAACCAAGTGGAAGGCGCCTA
TAATGTCGGCGGGAAAGGACTCTCGACAGCCGATGTGTCGCCGAACGGCGTCATGTATCCATTCGATGAGTCGATGGAGT
CATTGAACCTGTATCATGAAGGCATCGATTTTTACCACCGCTACAAAGAAGATATCGCTCTTTTCGCCGAAATGGGATTT
AAAGCATTCCGGACATCGATTGCCTGGACGCGGATTTTTCCTAACGGCGATGAAACTGAACCGAATGAAGAGGGACTCGA
ATTTTATGATCGCCTCTTTGACGAGCTATTAAAATACAATATTGAGCCAGTGGTGACGATTTCCCACTACGAAATGCCGC
TCGGTCTGATTAAAAAATACGGCGGCTGGAAAAACCGGAAAGTGATCGATTGCTATGAGCATTATGCGAAAACGGTTTTC
ACCCGCTATAAAGAAAAAGTAAAATACTGGATGACATTCAATGAAATCAACATGGTTCTGCATGCGCCGTTTACAGGCGG
AGGCCTTGTGTTTGAAGAAGGCGAAAACAAGTTAAATGCGATGTACCAAGCGGCGCATCATCTATTTGTCGCAAGCGCTC
TTGCCGTTAAAGCGGGGCACGACATCATTCCGGACGCTAAAATCGGCTGCATGATCGCCGCAACGACGACATACCCGATG
ACGCCAAAGCCGGAAGACGTGCTCGCTGCGATGGAGAATGAGAGAAGAACGCTGTTTTTCTCGGATGTACAGGCGCGCGG
GGCTTATCCGGGCTATATGAAGCGCTTCTTTAAGGAAAACGGAATTACGATTGAAATGGCTGAAGGTGATGAAGACATCT
TAAAGGAAAACACCGTCGACTATATCGGTTTCAGCTACTACATGTCAATGGTCGCAAGCACGAGTCCGGAAGACTTGGCA
AAAACGGAAGGCAACCTGCTCGGCGGCGTCAAAAATCCGTACCTTGAATCGTCCGAATGGGGCTGGCAGATCGATCCTAA
AGGGATCCGCATTACGCTGAATACATTGTACGACCGCTATCAAAAGCCGCTTTTCATTGTTGAAAACGGGCTCGGCGCCG
TCGATGTCGTCGAAGAAGACGGCTCCATCCAGGATGACTACAGAATCAACTATTTGCGCGATCATTTAAAAGAAGTAAGA
GAAGCCATTGCAGACGGCGTCGACTTAATCGGCTACACATCATGGGGCCCGATCGACCTGGTCAGCGCATCCACCGCCGA
AATGAAAAAGCGCTACGGCTATATTTACGTCGATCGTGACAATGAAGGAAAAGGCACGCTTTCAAGAACGAGAAAGAAAA
GCTTTTACTGGTATAAGAAAGTAATCGAAACGAATGGCGAGAGTTTGTGA

Upstream 100 bases:

>100_bases
AAACCTTTGAAATCAGATGAAAGCGTTGACATTGAGGAAGCGCTGATCGCGCTGGCGTAGAAAGAGGAAAGCCTGACAAA
TTTGGATGAGGTGAAATGAT

Downstream 100 bases:

>100_bases
TATACAGAATGGCTGTCCTTTACAGGACGGCCCTTTTTTTTCTCTGTAGCGCGTGAAAACAATTTGCTATACACTTGATT
TAGAAAATAGAAAAAAGCGC

Product: BglH

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTEQTKKFPEGFLWGGAVAANQVEGAYNVGGKGLSTADVSPNGVMYPFDESMESLNLYHEGIDFYHRYKEDIALFAEMGF
KAFRTSIAWTRIFPNGDETEPNEEGLEFYDRLFDELLKYNIEPVVTISHYEMPLGLIKKYGGWKNRKVIDCYEHYAKTVF
TRYKEKVKYWMTFNEINMVLHAPFTGGGLVFEEGENKLNAMYQAAHHLFVASALAVKAGHDIIPDAKIGCMIAATTTYPM
TPKPEDVLAAMENERRTLFFSDVQARGAYPGYMKRFFKENGITIEMAEGDEDILKENTVDYIGFSYYMSMVASTSPEDLA
KTEGNLLGGVKNPYLESSEWGWQIDPKGIRITLNTLYDRYQKPLFIVENGLGAVDVVEEDGSIQDDYRINYLRDHLKEVR
EAIADGVDLIGYTSWGPIDLVSASTAEMKKRYGYIYVDRDNEGKGTLSRTRKKSFYWYKKVIETNGESL

Sequences:

>Translated_469_residues
MTEQTKKFPEGFLWGGAVAANQVEGAYNVGGKGLSTADVSPNGVMYPFDESMESLNLYHEGIDFYHRYKEDIALFAEMGF
KAFRTSIAWTRIFPNGDETEPNEEGLEFYDRLFDELLKYNIEPVVTISHYEMPLGLIKKYGGWKNRKVIDCYEHYAKTVF
TRYKEKVKYWMTFNEINMVLHAPFTGGGLVFEEGENKLNAMYQAAHHLFVASALAVKAGHDIIPDAKIGCMIAATTTYPM
TPKPEDVLAAMENERRTLFFSDVQARGAYPGYMKRFFKENGITIEMAEGDEDILKENTVDYIGFSYYMSMVASTSPEDLA
KTEGNLLGGVKNPYLESSEWGWQIDPKGIRITLNTLYDRYQKPLFIVENGLGAVDVVEEDGSIQDDYRINYLRDHLKEVR
EAIADGVDLIGYTSWGPIDLVSASTAEMKKRYGYIYVDRDNEGKGTLSRTRKKSFYWYKKVIETNGESL
>Mature_468_residues
TEQTKKFPEGFLWGGAVAANQVEGAYNVGGKGLSTADVSPNGVMYPFDESMESLNLYHEGIDFYHRYKEDIALFAEMGFK
AFRTSIAWTRIFPNGDETEPNEEGLEFYDRLFDELLKYNIEPVVTISHYEMPLGLIKKYGGWKNRKVIDCYEHYAKTVFT
RYKEKVKYWMTFNEINMVLHAPFTGGGLVFEEGENKLNAMYQAAHHLFVASALAVKAGHDIIPDAKIGCMIAATTTYPMT
PKPEDVLAAMENERRTLFFSDVQARGAYPGYMKRFFKENGITIEMAEGDEDILKENTVDYIGFSYYMSMVASTSPEDLAK
TEGNLLGGVKNPYLESSEWGWQIDPKGIRITLNTLYDRYQKPLFIVENGLGAVDVVEEDGSIQDDYRINYLRDHLKEVRE
AIADGVDLIGYTSWGPIDLVSASTAEMKKRYGYIYVDRDNEGKGTLSRTRKKSFYWYKKVIETNGESL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=478, Percent_Identity=28.8702928870293, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI110681710, Length=487, Percent_Identity=29.7741273100616, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI28376633, Length=475, Percent_Identity=28.8421052631579, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13273313, Length=481, Percent_Identity=25.987525987526, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI24497614, Length=478, Percent_Identity=28.4518828451883, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI2367270, Length=465, Percent_Identity=64.7311827956989, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1789070, Length=471, Percent_Identity=57.3248407643312, Blast_Score=583, Evalue=1e-168,
Organism=Escherichia coli, GI2367174, Length=480, Percent_Identity=56.4583333333333, Blast_Score=537, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI17552856, Length=486, Percent_Identity=30.0411522633745, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17539390, Length=482, Percent_Identity=29.6680497925311, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21356577, Length=493, Percent_Identity=27.9918864097363, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53393; Mature: 53262

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTKKFPEGFLWGGAVAANQVEGAYNVGGKGLSTADVSPNGVMYPFDESMESLNLYHE
CCCCCHHCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
GIDFYHRYKEDIALFAEMGFKAFRTSIAWTRIFPNGDETEPNEEGLEFYDRLFDELLKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVVTISHYEMPLGLIKKYGGWKNRKVIDCYEHYAKTVFTRYKEKVKYWMTFNEINMVL
CCEEEEEECCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEE
HAPFTGGGLVFEEGENKLNAMYQAAHHLFVASALAVKAGHDIIPDAKIGCMIAATTTYPM
ECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
TPKPEDVLAAMENERRTLFFSDVQARGAYPGYMKRFFKENGITIEMAEGDEDILKENTVD
CCCHHHHHHHHHCCCCEEEEECHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHHCCCHH
YIGFSYYMSMVASTSPEDLAKTEGNLLGGVKNPYLESSEWGWQIDPKGIRITLNTLYDRY
HHHHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHH
QKPLFIVENGLGAVDVVEEDGSIQDDYRINYLRDHLKEVREAIADGVDLIGYTSWGPIDL
CCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEE
VSASTAEMKKRYGYIYVDRDNEGKGTLSRTRKKSFYWYKKVIETNGESL
ECCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TEQTKKFPEGFLWGGAVAANQVEGAYNVGGKGLSTADVSPNGVMYPFDESMESLNLYHE
CCCCHHCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
GIDFYHRYKEDIALFAEMGFKAFRTSIAWTRIFPNGDETEPNEEGLEFYDRLFDELLKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVVTISHYEMPLGLIKKYGGWKNRKVIDCYEHYAKTVFTRYKEKVKYWMTFNEINMVL
CCEEEEEECCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEE
HAPFTGGGLVFEEGENKLNAMYQAAHHLFVASALAVKAGHDIIPDAKIGCMIAATTTYPM
ECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
TPKPEDVLAAMENERRTLFFSDVQARGAYPGYMKRFFKENGITIEMAEGDEDILKENTVD
CCCHHHHHHHHHCCCCEEEEECHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHHCCCHH
YIGFSYYMSMVASTSPEDLAKTEGNLLGGVKNPYLESSEWGWQIDPKGIRITLNTLYDRY
HHHHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHH
QKPLFIVENGLGAVDVVEEDGSIQDDYRINYLRDHLKEVREAIADGVDLIGYTSWGPIDL
CCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEE
VSASTAEMKKRYGYIYVDRDNEGKGTLSRTRKKSFYWYKKVIETNGESL
ECCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]