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The map label for this gene is fabZ

Identifier: 52787552

GI number: 52787552

Start: 3697130

End: 3697564

Strand: Reverse

Name: fabZ

Synonym: BLi03873

Alternate gene names: 52787552

Gene position: 3697564-3697130 (Counterclockwise)

Preceding gene: 52787553

Following gene: 52787551

Centisome position: 87.57

GC content: 47.82

Gene sequence:

>435_bases
ATGCTTGATGCTCAGCAAATTAAAGAAATCATTCCCCACCGCTATCCCTTTCTGCTGGTAGACCGTGTGACAGAAGTAGA
GGAAGGAAAACGGGCCGCGGGTTATAAAAATGTGACAGTAAATGAAGAGTTTTTTAACGGACACTTTCCGGATTATCCGG
TGATGCCTGGTGTTTTAATTGTTGAAGCGCTTGCGCAAGTAGGTGCGGTGGCGCTTTTGATGAAGGAAGAAAACCGCGGA
AGGCTCGCGTTTTTTGCGGGAATTGACAGCTGCCGCTTCAAAAAGCAGGTGAAACCGGGCGATCAGCTCCATCTTGAGCT
TGAAGTGCTTCGTTTCCGCGGTTCCATCGGCAAAGGAAAAGGAGTCGCAAAAGTGGACGGAGAAGTCGTGTGTGAAGCCG
AATTGATGTTTTCTCTTGGTGAAAAGCAGGAATAA

Upstream 100 bases:

>100_bases
TTGAAAAAGATTCCGTTTCATAATATACTTCCAGATGTACAGAATAAGGCACTGACATATCATTCTATACATATTTTTCG
AAAAAGGAGATGTCAAGGCA

Downstream 100 bases:

>100_bases
TGTAAACACAATGGGTTTTCGTAAAAGCCCATTTGTTTTTTTATCATGAAAGCGAAAAGGTGATCATTCATGTGGAAAGA
ATTTAAAAGTTTTGCGATTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLDAQQIKEIIPHRYPFLLVDRVTEVEEGKRAAGYKNVTVNEEFFNGHFPDYPVMPGVLIVEALAQVGAVALLMKEENRG
RLAFFAGIDSCRFKKQVKPGDQLHLELEVLRFRGSIGKGKGVAKVDGEVVCEAELMFSLGEKQE

Sequences:

>Translated_144_residues
MLDAQQIKEIIPHRYPFLLVDRVTEVEEGKRAAGYKNVTVNEEFFNGHFPDYPVMPGVLIVEALAQVGAVALLMKEENRG
RLAFFAGIDSCRFKKQVKPGDQLHLELEVLRFRGSIGKGKGVAKVDGEVVCEAELMFSLGEKQE
>Mature_144_residues
MLDAQQIKEIIPHRYPFLLVDRVTEVEEGKRAAGYKNVTVNEEFFNGHFPDYPVMPGVLIVEALAQVGAVALLMKEENRG
RLAFFAGIDSCRFKKQVKPGDQLHLELEVLRFRGSIGKGKGVAKVDGEVVCEAELMFSLGEKQE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=51.4492753623188, Blast_Score=138, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_BACLD (Q65E26)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080951.1
- RefSeq:   YP_093381.1
- ProteinModelPortal:   Q65E26
- SMR:   Q65E26
- STRING:   Q65E26
- EnsemblBacteria:   EBBACT00000055037
- EnsemblBacteria:   EBBACT00000060908
- GeneID:   3028437
- GeneID:   3101084
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03873
- KEGG:   bli:BL02496
- NMPDR:   fig|279010.5.peg.4065
- eggNOG:   COG0764
- GeneTree:   EBGT00050000002061
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   BLIC279010-1:BLI03873-MONOMER
- BioCyc:   BLIC279010:BL02496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16092; Mature: 16092

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDAQQIKEIIPHRYPFLLVDRVTEVEEGKRAAGYKNVTVNEEFFNGHFPDYPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCCEECHHHCCCCCCCCCCCCHHHH
VEALAQVGAVALLMKEENRGRLAFFAGIDSCRFKKQVKPGDQLHLELEVLRFRGSIGKGK
HHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCEEEEEEEEEECCCCCCCC
GVAKVDGEVVCEAELMFSLGEKQE
CEEEECCCEEEHHHHHHHCCCCCC
>Mature Secondary Structure
MLDAQQIKEIIPHRYPFLLVDRVTEVEEGKRAAGYKNVTVNEEFFNGHFPDYPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCCEECHHHCCCCCCCCCCCCHHHH
VEALAQVGAVALLMKEENRGRLAFFAGIDSCRFKKQVKPGDQLHLELEVLRFRGSIGKGK
HHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCEEEEEEEEEECCCCCCCC
GVAKVDGEVVCEAELMFSLGEKQE
CEEEECCCEEEHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA