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The map label for this gene is trxB [H]

Identifier: 52787411

GI number: 52787411

Start: 3552591

End: 3553541

Strand: Reverse

Name: trxB [H]

Synonym: BLi03728

Alternate gene names: 52787411

Gene position: 3553541-3552591 (Counterclockwise)

Preceding gene: 52787412

Following gene: 52787409

Centisome position: 84.15

GC content: 48.48

Gene sequence:

>951_bases
GTGTCAGAAGAAAAAATGTATGACGTCATTATTATAGGAGCAGGTCCTGCGGGAATGACGGCAGCCGTTTATACGTCAAG
GGCGAACCTGTCGACTTTGATGGTTGAAAGAGGCGTTCCGGGCGGACAGATGGCCAATACGGAGGATGTTGAAAACTATC
CGGGATTTGAAAGCATTCTGGGACCCGAGCTTTCAAATAAAATGTTTGAACATGCGAAAAAGTTCGGCGCTGAGTATGCG
TACGGCGATATTAAAGAAGTCGTCGATGAAGGAGACTATAAGATCGTCAAAGCGGGATCAAAAGAATTTAAAGCGCGCGC
GGTCATCATCACAGCAGGCGCCGAATATAAGAAGCTCGGCGTACCTGGCGAAAAAGAGCTTGGCGGCCGCGGCGTTTCTT
ATTGTGCGGTTTGTGACGGCGCCTTCTTTAAAAACAAAGAGCTGGTCGTTGTCGGAGGAGGAGACTCCGCTGTTGAAGAA
GGCGTGTACTTAACCCGTTTCGCTTCGAAAGTAACAATCGTCCATCGCCGCGATAAGCTGAGAGCGCAAAGCATTCTTCA
GGCGCGCGCGTTTGACAACGAAAAAGTCGACTTTCTCTGGAATAAGACGGTCAAGGAAATTCATGAACAAGACGGAAAAG
TCGGCAAAGTGACACTGGTCGATACGGTCACAGGCGAAGAAGAAGAGTTCCGGACTGACGGCGTCTTTATCTACATCGGT
ATGCTCCCGCTTTCAGAGCCTTTCAAAAACCTCGGCATTACAAATGAAGAGGGCTACATCGTGACAAATGAACAGATGGA
AACAAAAGTCGAAGGCATTTTTGCTGCGGGAGACATTCGCGAGAAAACCCTTCGCCAAATCGTAACGGCAACAGGGGACG
GAAGCATTGCCGCACAGAGCGTTCAGCACTATATCGAAGAGCTGAAAGAGAAAGAAAAGGCTGTAAAATAA

Upstream 100 bases:

>100_bases
GATATTTTATAGGATATGGGTAAGGAAGTTATAAGAAGGGAATCTTATTTAACAGGAATGCACTGCTTGCAAGCATAAGA
TTCATGAAGGAGTGAACATT

Downstream 100 bases:

>100_bases
CGCATTTTAATCGTCATCATGATTTAACCGGCCTGTAACACCAGTGAAACAATTATTCGTTATGATTGGTATAGTAATTG
ACCCCCTTTTATAATGAATT

Product: hypothetical protein

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSEEKMYDVIIIGAGPAGMTAAVYTSRANLSTLMVERGVPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYA
YGDIKEVVDEGDYKIVKAGSKEFKARAVIITAGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKNKELVVVGGGDSAVEE
GVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEQDGKVGKVTLVDTVTGEEEEFRTDGVFIYIG
MLPLSEPFKNLGITNEEGYIVTNEQMETKVEGIFAAGDIREKTLRQIVTATGDGSIAAQSVQHYIEELKEKEKAVK

Sequences:

>Translated_316_residues
MSEEKMYDVIIIGAGPAGMTAAVYTSRANLSTLMVERGVPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYA
YGDIKEVVDEGDYKIVKAGSKEFKARAVIITAGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKNKELVVVGGGDSAVEE
GVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEQDGKVGKVTLVDTVTGEEEEFRTDGVFIYIG
MLPLSEPFKNLGITNEEGYIVTNEQMETKVEGIFAAGDIREKTLRQIVTATGDGSIAAQSVQHYIEELKEKEKAVK
>Mature_315_residues
SEEKMYDVIIIGAGPAGMTAAVYTSRANLSTLMVERGVPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYAY
GDIKEVVDEGDYKIVKAGSKEFKARAVIITAGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKNKELVVVGGGDSAVEEG
VYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEQDGKVGKVTLVDTVTGEEEEFRTDGVFIYIGM
LPLSEPFKNLGITNEEGYIVTNEQMETKVEGIFAAGDIREKTLRQIVTATGDGSIAAQSVQHYIEELKEKEKAVK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=24.1590214067278, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=24.1590214067278, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=24.1590214067278, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=37.5, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=33.4405144694534, Blast_Score=162, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=38.8888888888889, Blast_Score=200, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=38.4146341463415, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34635; Mature: 34504

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKMYDVIIIGAGPAGMTAAVYTSRANLSTLMVERGVPGGQMANTEDVENYPGFESIL
CCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
GPELSNKMFEHAKKFGAEYAYGDIKEVVDEGDYKIVKAGSKEFKARAVIITAGAEYKKLG
CCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKNKELVVVGGGDSAVEEGVYLTRFASKVTIVHRRDKL
CCCCHHCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHCCEEEEEHHHHEEEEEHHHHH
RAQSILQARAFDNEKVDFLWNKTVKEIHEQDGKVGKVTLVDTVTGEEEEFRTDGVFIYIG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHCCCCEEEEEE
MLPLSEPFKNLGITNEEGYIVTNEQMETKVEGIFAAGDIREKTLRQIVTATGDGSIAAQS
ECCCCCHHHHCCCCCCCCEEEECHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCHHHHH
VQHYIEELKEKEKAVK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEEKMYDVIIIGAGPAGMTAAVYTSRANLSTLMVERGVPGGQMANTEDVENYPGFESIL
CCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
GPELSNKMFEHAKKFGAEYAYGDIKEVVDEGDYKIVKAGSKEFKARAVIITAGAEYKKLG
CCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKNKELVVVGGGDSAVEEGVYLTRFASKVTIVHRRDKL
CCCCHHCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHCCEEEEEHHHHEEEEEHHHHH
RAQSILQARAFDNEKVDFLWNKTVKEIHEQDGKVGKVTLVDTVTGEEEEFRTDGVFIYIG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHCCCCEEEEEE
MLPLSEPFKNLGITNEEGYIVTNEQMETKVEGIFAAGDIREKTLRQIVTATGDGSIAAQS
ECCCCCHHHHCCCCCCCCEEEECHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCHHHHH
VQHYIEELKEKEKAVK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]