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The map label for this gene is ilvC [H]

Identifier: 52786691

GI number: 52786691

Start: 2847499

End: 2848527

Strand: Reverse

Name: ilvC [H]

Synonym: BLi02959

Alternate gene names: 52786691

Gene position: 2848527-2847499 (Counterclockwise)

Preceding gene: 52786692

Following gene: 52786690

Centisome position: 67.46

GC content: 48.79

Gene sequence:

>1029_bases
ATGGTAAAAGTATATTATAACGGTGATATCAAAGAAAACGTATTAGCAGGCAAAAAAGTAGCGGTGATCGGATACGGCTC
ACAAGGCCATGCGCACGCACTGAACCTGAAAGAAAGCGGAGTGGACGTCATTGTCGGCGTCAGAAAAGGGAAATCCTTTG
CAAAAGCAGAGGAAGACGGCCATCAAGTTTTCACGGTAAGAGAAGCGGCAGAACAGGCCGACATCGTCATGGTGCTTCTT
CCGGATGAACAGCAGCAAAAAGTGTATGAAGCGGAAATTAAAGACGGACTTCAAGCTGGCAATTCACTTGTATTCGCCCA
CGGATTCAACGTTCATTTCCATCAGATCGTGCCTCCGGCGGATGTTGACGTATTCCTTGTCGCTCCTAAAGGACCGGGAC
ATCTTGTCAGAAGAACGTTTGAACAAGGTGCGGGGGTTCCGGCGCTGTTTGCGATCTATCAGGATGTGACAGGGGAAGCG
AAAGACAAAGCCCTTGCTTATGCTAAAGCGATCGGCGGCGCAAGAGCCGGTGTTCTTGAAACAACATTTAAAGAAGAAAC
TGAAACCGATCTTTTCGGAGAACAGGCGGTGCTGTGCGGAGGATTGACTTCCCTTGTCAAAGCCGGGTTCGAAACGCTGA
CAGAAGCGGGCTATCAGCCTGAACTCGCATACTTCGAGTGTCTGCACGAGCTGAAGCTCATCGTCGACTTGATGTATGAA
GAAGGTTTGGCAGGGATGAGATATTCGATTTCCGACACAGCGCAGTGGGGAGACTTCGTATCAGGTCCGCGCGTTGTCGA
TGAGAAGGTAAAAGAATCAATGAAAGAAGTATTGAAAGACATCCAAAACGGTACATTCGCAAAAGAGTGGATCGTCGAAA
ACCAAGTCAACCGTCCGCGTTTCAACGCCATCAATGCAAGCGAAAACGAACACCAAATCGAAGTGGTCGGCAGAAAGCTT
CGCGAAATGATGCCGTTTGTCAAGCAGGGCAAGAAAAAGGAAGCGGTGGTAGCCGGTGCGAAAAATTAA

Upstream 100 bases:

>100_bases
CCAGAACAGGCACCACGGCCTTTGCGAGGGGAACTCAGCAAAAGCCGGCCTCTATTAAAACAATATCTATTGTATAAATC
ATAAAAAGGGAGAGATTGAA

Downstream 100 bases:

>100_bases
CTTTTTTGATACGACACTCCGTGACGGTGAACAGTCGCCGGGCGTTAATTTAAACACGCAGGAGAAGCTGGCGATCGCCC
AGCAGCTTGAAAAACTCGGG

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVKVYYNGDIKENVLAGKKVAVIGYGSQGHAHALNLKESGVDVIVGVRKGKSFAKAEEDGHQVFTVREAAEQADIVMVLL
PDEQQQKVYEAEIKDGLQAGNSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTFEQGAGVPALFAIYQDVTGEA
KDKALAYAKAIGGARAGVLETTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDEKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVAGAKN

Sequences:

>Translated_342_residues
MVKVYYNGDIKENVLAGKKVAVIGYGSQGHAHALNLKESGVDVIVGVRKGKSFAKAEEDGHQVFTVREAAEQADIVMVLL
PDEQQQKVYEAEIKDGLQAGNSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTFEQGAGVPALFAIYQDVTGEA
KDKALAYAKAIGGARAGVLETTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDEKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVAGAKN
>Mature_342_residues
MVKVYYNGDIKENVLAGKKVAVIGYGSQGHAHALNLKESGVDVIVGVRKGKSFAKAEEDGHQVFTVREAAEQADIVMVLL
PDEQQQKVYEAEIKDGLQAGNSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTFEQGAGVPALFAIYQDVTGEA
KDKALAYAKAIGGARAGVLETTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDEKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVAGAKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=287, Percent_Identity=35.8885017421603, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323387, Length=318, Percent_Identity=36.4779874213836, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37469; Mature: 37469

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVYYNGDIKENVLAGKKVAVIGYGSQGHAHALNLKESGVDVIVGVRKGKSFAKAEEDG
CEEEEECCCCHHHHHCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCCCHHHCCCCC
HQVFTVREAAEQADIVMVLLPDEQQQKVYEAEIKDGLQAGNSLVFAHGFNVHFHQIVPPA
CEEEEEHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCC
DVDVFLVAPKGPGHLVRRTFEQGAGVPALFAIYQDVTGEAKDKALAYAKAIGGARAGVLE
CCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHH
TTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EGLAGMRYSISDTAQWGDFVSGPRVVDEKVKESMKEVLKDIQNGTFAKEWIVENQVNRPR
CCCCCCEEECCCCHHHCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
FNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVAGAKN
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MVKVYYNGDIKENVLAGKKVAVIGYGSQGHAHALNLKESGVDVIVGVRKGKSFAKAEEDG
CEEEEECCCCHHHHHCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCCCHHHCCCCC
HQVFTVREAAEQADIVMVLLPDEQQQKVYEAEIKDGLQAGNSLVFAHGFNVHFHQIVPPA
CEEEEEHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCC
DVDVFLVAPKGPGHLVRRTFEQGAGVPALFAIYQDVTGEAKDKALAYAKAIGGARAGVLE
CCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHH
TTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EGLAGMRYSISDTAQWGDFVSGPRVVDEKVKESMKEVLKDIQNGTFAKEWIVENQVNRPR
CCCCCCEEECCCCHHHCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
FNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVAGAKN
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA