Click here to switch to the map view.

The map label for this gene is yrvO [H]

Identifier: 52786610

GI number: 52786610

Start: 2765517

End: 2766656

Strand: Reverse

Name: yrvO [H]

Synonym: BLi02876

Alternate gene names: 52786610

Gene position: 2766656-2765517 (Counterclockwise)

Preceding gene: 52786611

Following gene: 52786609

Centisome position: 65.52

GC content: 52.37

Gene sequence:

>1140_bases
ATGGAACGGATTTACTTAGACCATGCAGCGACTTCTCCGACTGACCCCCGGGTAGTGGAAAAAATGCTGCCTTACTTAAC
GGAAAACTTCGGAAACCCTTCAAGCATTCATTCCTTTGGAAGGGAGAGCCGGAAATGGCTTGACAGCACGAGGGAGCTGA
TCGCTCAGGAAATCGGAGCGCATCCCAATGAAATCGTTTTTACGAGCGGGGGAACCGAAGCCGACAATATGGCGATTCTC
GGAAGCGCGCTGGCGAGAGAGAAGCAGGGCCGCCACATCATCACGACAAAGATCGAGCACCATGCCGTTCTGCATACGTG
CAACAGGCTTGAAGAAATGGGATTTGACGTCACATATCTAGACGTCGACGAAAGCGGAAGAATCTCCGCCGAGCAGGTGA
AAGACGCACTGCGAGACGATACCATCCTGGTGACGGTTATGTATGGGAACAATGAAGTGGGAACGATTCAGCCGATAGAT
GAGATCGGCGATCTGCTAAAGGACCATCCCGCGCTGTTTCATACAGATGCGGTTCAAGCCTTCGGTTTTTTGCCGATTGA
TGTGCAAAAAAGCCGTATCGATATGATGTCTGTCTCCGGACATAAACTTAACGGGCCGAAGGGAACAGGCTTTTTATACG
TCAACGAAAACGTGAAGCTCAGCCAGCTTCTTTTCGGAGGAGAGCAGGAACGCAAACGCCGGGCGGGAACGGAAAATGTC
CCGGGAATCGCGGGGCTCGGTGAAGCTGTTTTGCTCTCGGGTCGGGAAAGAGAAGAAAAATCGGATCTTTACCGCCGGTT
TAAAGACATCATCACCCGTACGCTGGAAGCAGAAGGCGTCTCATTCGATGTGAACGGCAGCAGGCGGCACAGTCTGCCGC
ATATTTTGAATCTGTATTTCCCGGGAGTATCTGTTGAATCGCTGCTCGTCAATCTCGATATGGCGGGAATCGCAGTATCG
AGCGGATCGGCGTGCACGGCCGGGTCTGTGCTTCCGTCTCATGTTCTCTCCGCCATGTTTGGCGAAGAAGACGATCGGCT
CACGTCATCCGTCCGGATCAGCTTCGGCTTTGGCAATACAGAGGAACAGGTTGAGCGCGCCGCGAAAGAACTTGCTAAAG
TTGTTAAGCGTCTGTCATAA

Upstream 100 bases:

>100_bases
AAGTGCTGGACTCCACGACGCTTGAAGACTTGGCCAGCTATACAGAGGGCGAGCAGGAAGCGTATATGTTTTACATTTAA
GATCGAGGTGTAATGGTAGG

Downstream 100 bases:

>100_bases
ATTTCGGGAAGCCATGCTCCGAGCTAAAGATTCGCATCCTGCCCGAAAATGATGATATGATCTGAAAGGACAAGTTTTTG
AATTGATTTATTGGAGTTGA

Product: YrvO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MERIYLDHAATSPTDPRVVEKMLPYLTENFGNPSSIHSFGRESRKWLDSTRELIAQEIGAHPNEIVFTSGGTEADNMAIL
GSALAREKQGRHIITTKIEHHAVLHTCNRLEEMGFDVTYLDVDESGRISAEQVKDALRDDTILVTVMYGNNEVGTIQPID
EIGDLLKDHPALFHTDAVQAFGFLPIDVQKSRIDMMSVSGHKLNGPKGTGFLYVNENVKLSQLLFGGEQERKRRAGTENV
PGIAGLGEAVLLSGREREEKSDLYRRFKDIITRTLEAEGVSFDVNGSRRHSLPHILNLYFPGVSVESLLVNLDMAGIAVS
SGSACTAGSVLPSHVLSAMFGEEDDRLTSSVRISFGFGNTEEQVERAAKELAKVVKRLS

Sequences:

>Translated_379_residues
MERIYLDHAATSPTDPRVVEKMLPYLTENFGNPSSIHSFGRESRKWLDSTRELIAQEIGAHPNEIVFTSGGTEADNMAIL
GSALAREKQGRHIITTKIEHHAVLHTCNRLEEMGFDVTYLDVDESGRISAEQVKDALRDDTILVTVMYGNNEVGTIQPID
EIGDLLKDHPALFHTDAVQAFGFLPIDVQKSRIDMMSVSGHKLNGPKGTGFLYVNENVKLSQLLFGGEQERKRRAGTENV
PGIAGLGEAVLLSGREREEKSDLYRRFKDIITRTLEAEGVSFDVNGSRRHSLPHILNLYFPGVSVESLLVNLDMAGIAVS
SGSACTAGSVLPSHVLSAMFGEEDDRLTSSVRISFGFGNTEEQVERAAKELAKVVKRLS
>Mature_379_residues
MERIYLDHAATSPTDPRVVEKMLPYLTENFGNPSSIHSFGRESRKWLDSTRELIAQEIGAHPNEIVFTSGGTEADNMAIL
GSALAREKQGRHIITTKIEHHAVLHTCNRLEEMGFDVTYLDVDESGRISAEQVKDALRDDTILVTVMYGNNEVGTIQPID
EIGDLLKDHPALFHTDAVQAFGFLPIDVQKSRIDMMSVSGHKLNGPKGTGFLYVNENVKLSQLLFGGEQERKRRAGTENV
PGIAGLGEAVLLSGREREEKSDLYRRFKDIITRTLEAEGVSFDVNGSRRHSLPHILNLYFPGVSVESLLVNLDMAGIAVS
SGSACTAGSVLPSHVLSAMFGEEDDRLTSSVRISFGFGNTEEQVERAAKELAKVVKRLS

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=378, Percent_Identity=42.8571428571429, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI156713448, Length=415, Percent_Identity=33.0120481927711, Blast_Score=195, Evalue=5e-50,
Organism=Escherichia coli, GI48994898, Length=381, Percent_Identity=44.3569553805774, Blast_Score=300, Evalue=7e-83,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=26.1083743842365, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789175, Length=384, Percent_Identity=26.0416666666667, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25143064, Length=379, Percent_Identity=43.5356200527704, Blast_Score=300, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI17533177, Length=323, Percent_Identity=31.5789473684211, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319831, Length=379, Percent_Identity=44.5910290237467, Blast_Score=298, Evalue=8e-82,
Organism=Drosophila melanogaster, GI20129463, Length=383, Percent_Identity=44.1253263707572, Blast_Score=290, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41705; Mature: 41705

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIYLDHAATSPTDPRVVEKMLPYLTENFGNPSSIHSFGRESRKWLDSTRELIAQEIGA
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPNEIVFTSGGTEADNMAILGSALAREKQGRHIITTKIEHHAVLHTCNRLEEMGFDVTYL
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEE
DVDESGRISAEQVKDALRDDTILVTVMYGNNEVGTIQPIDEIGDLLKDHPALFHTDAVQA
ECCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHH
FGFLPIDVQKSRIDMMSVSGHKLNGPKGTGFLYVNENVKLSQLLFGGEQERKRRAGTENV
HCCCCEECCHHHEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHCCCCCC
PGIAGLGEAVLLSGREREEKSDLYRRFKDIITRTLEAEGVSFDVNGSRRHSLPHILNLYF
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHC
PGVSVESLLVNLDMAGIAVSSGSACTAGSVLPSHVLSAMFGEEDDRLTSSVRISFGFGNT
CCCCHHHHHEECCHHCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
EEQVERAAKELAKVVKRLS
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERIYLDHAATSPTDPRVVEKMLPYLTENFGNPSSIHSFGRESRKWLDSTRELIAQEIGA
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPNEIVFTSGGTEADNMAILGSALAREKQGRHIITTKIEHHAVLHTCNRLEEMGFDVTYL
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEE
DVDESGRISAEQVKDALRDDTILVTVMYGNNEVGTIQPIDEIGDLLKDHPALFHTDAVQA
ECCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHH
FGFLPIDVQKSRIDMMSVSGHKLNGPKGTGFLYVNENVKLSQLLFGGEQERKRRAGTENV
HCCCCEECCHHHEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHCCCCCC
PGIAGLGEAVLLSGREREEKSDLYRRFKDIITRTLEAEGVSFDVNGSRRHSLPHILNLYF
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHC
PGVSVESLLVNLDMAGIAVSSGSACTAGSVLPSHVLSAMFGEEDDRLTSSVRISFGFGNT
CCCCHHHHHEECCHHCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
EEQVERAAKELAKVVKRLS
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]