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The map label for this gene is gsiC [H]

Identifier: 52786266

GI number: 52786266

Start: 2449381

End: 2450322

Strand: Direct

Name: gsiC [H]

Synonym: BLi02528

Alternate gene names: 52786266

Gene position: 2449381-2450322 (Clockwise)

Preceding gene: 52786265

Following gene: 52786267

Centisome position: 58.01

GC content: 51.8

Gene sequence:

>942_bases
ATGAAGCAGATCGCCAAGCGGCTGTTTGAACTGGTCCTGTTCTTATTCCTGCTTTCATTTATCAGCTTTGTGTTTATGAA
AGCGGCTCCCGGTGATCCGGTGAAACAGATGCTTCGCGTAGATGATGTTGCGGTAACGGACGAGCAGATCGAGGCATTCA
GAGAGGAGCTCGGTTTGGACAAACCGGTTTATATTCAATATTGGAACTGGTTCAAGCGCTTTTTCCAATTTGATTTGGGA
AAATCCTATACAACACACGAACCCGTCATCGACGAGCTCAGCCGGAAATTCCCGGCGACATTGCTTCTAACCGGCGCATC
GCTTCTCGTTATGCTGCTGATTGCCGTGCCGGTCGGAACGCTTTCCGCTTTATACCGGGATCGGTGGATCGATCATCTCA
GCCGCTTGCTCGCTTTAGTGGGAGCCGCGCTCCCGAGCTTTTGGCTCGGATTGATACTGATCGATCTCTTTTCCGTCAGG
CTGAATTGGCTGCCGTCGATGGGAGCCGGAACGTTTAAACATTTGATTCTCCCCTCTCTCACGCTTGGGATCGCGATGTC
GGGCGTTTATGTCCGCCTTGTACGGTCAAGCCTGATCGAAAGCCTTGGTCAGGATTTCATCAGATCTGCCAGGGCACGCG
GCATCAGCGAGGCGAGAATTTTCTTCTTTCACGCGTTTCGCCATTGTCTTGTCCCTGTCATCACGATATTCGGGGTCAGC
CTCGGCAGCCTGCTCGGCGGCACGGTGATTATTGAAGTCCTGTTTGCATATCCCGGCGTCGGCAAGCTTGTCGTTGATGC
CATCGTTCAGCGTGATTATCCGATCATTCAGGGGTACATTCTTTTCATGGGGATCGCGGTTGTCCTGATCAATCTTTTAG
TCGACCTCTCTTATCGGTACCTCAATCCGGAAATTCGCTTAAAGGAGGCTGGTCGCCGATGA

Upstream 100 bases:

>100_bases
CTCCCGAAAACATCACAGCCTACCGAGACGGTGTATTAAATTGGGAAACGAGCAAAAGTGAGTATTATATGCTGACGAAA
GATTTGGATGTGAAAACGAA

Downstream 100 bases:

>100_bases
GAAAAAACGTATTTCGATCTAAAACAGGACTATGGTTTGTGCTGCTGTTTTCCGCGGCGCTGTTCACCGTCCCCTTCTTT
TTGCCGTTCGATCCGCTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKQIAKRLFELVLFLFLLSFISFVFMKAAPGDPVKQMLRVDDVAVTDEQIEAFREELGLDKPVYIQYWNWFKRFFQFDLG
KSYTTHEPVIDELSRKFPATLLLTGASLLVMLLIAVPVGTLSALYRDRWIDHLSRLLALVGAALPSFWLGLILIDLFSVR
LNWLPSMGAGTFKHLILPSLTLGIAMSGVYVRLVRSSLIESLGQDFIRSARARGISEARIFFFHAFRHCLVPVITIFGVS
LGSLLGGTVIIEVLFAYPGVGKLVVDAIVQRDYPIIQGYILFMGIAVVLINLLVDLSYRYLNPEIRLKEAGRR

Sequences:

>Translated_313_residues
MKQIAKRLFELVLFLFLLSFISFVFMKAAPGDPVKQMLRVDDVAVTDEQIEAFREELGLDKPVYIQYWNWFKRFFQFDLG
KSYTTHEPVIDELSRKFPATLLLTGASLLVMLLIAVPVGTLSALYRDRWIDHLSRLLALVGAALPSFWLGLILIDLFSVR
LNWLPSMGAGTFKHLILPSLTLGIAMSGVYVRLVRSSLIESLGQDFIRSARARGISEARIFFFHAFRHCLVPVITIFGVS
LGSLLGGTVIIEVLFAYPGVGKLVVDAIVQRDYPIIQGYILFMGIAVVLINLLVDLSYRYLNPEIRLKEAGRR
>Mature_313_residues
MKQIAKRLFELVLFLFLLSFISFVFMKAAPGDPVKQMLRVDDVAVTDEQIEAFREELGLDKPVYIQYWNWFKRFFQFDLG
KSYTTHEPVIDELSRKFPATLLLTGASLLVMLLIAVPVGTLSALYRDRWIDHLSRLLALVGAALPSFWLGLILIDLFSVR
LNWLPSMGAGTFKHLILPSLTLGIAMSGVYVRLVRSSLIESLGQDFIRSARARGISEARIFFFHAFRHCLVPVITIFGVS
LGSLLGGTVIIEVLFAYPGVGKLVVDAIVQRDYPIIQGYILFMGIAVVLINLLVDLSYRYLNPEIRLKEAGRR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=309, Percent_Identity=41.1003236245955, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI1789888, Length=312, Percent_Identity=38.4615384615385, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=36.0703812316716, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=38.9057750759878, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1787497, Length=309, Percent_Identity=30.7443365695793, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=29.9638989169675, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788504, Length=357, Percent_Identity=25.2100840336134, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35329; Mature: 35329

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIAKRLFELVLFLFLLSFISFVFMKAAPGDPVKQMLRVDDVAVTDEQIEAFREELGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KPVYIQYWNWFKRFFQFDLGKSYTTHEPVIDELSRKFPATLLLTGASLLVMLLIAVPVGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSALYRDRWIDHLSRLLALVGAALPSFWLGLILIDLFSVRLNWLPSMGAGTFKHLILPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TLGIAMSGVYVRLVRSSLIESLGQDFIRSARARGISEARIFFFHAFRHCLVPVITIFGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLLGGTVIIEVLFAYPGVGKLVVDAIVQRDYPIIQGYILFMGIAVVLINLLVDLSYRY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPEIRLKEAGRR
CCCCHHHHCCCCC
>Mature Secondary Structure
MKQIAKRLFELVLFLFLLSFISFVFMKAAPGDPVKQMLRVDDVAVTDEQIEAFREELGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KPVYIQYWNWFKRFFQFDLGKSYTTHEPVIDELSRKFPATLLLTGASLLVMLLIAVPVGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSALYRDRWIDHLSRLLALVGAALPSFWLGLILIDLFSVRLNWLPSMGAGTFKHLILPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TLGIAMSGVYVRLVRSSLIESLGQDFIRSARARGISEARIFFFHAFRHCLVPVITIFGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLLGGTVIIEVLFAYPGVGKLVVDAIVQRDYPIIQGYILFMGIAVVLINLLVDLSYRY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPEIRLKEAGRR
CCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]