Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 52786240

GI number: 52786240

Start: 2430944

End: 2431834

Strand: Reverse

Name: xerD [H]

Synonym: BLi02501

Alternate gene names: 52786240

Gene position: 2431834-2430944 (Counterclockwise)

Preceding gene: 52786241

Following gene: 52786239

Centisome position: 57.59

GC content: 51.07

Gene sequence:

>891_bases
GTGAAAGTTCATATTAAAGACTTTATCCACTACGCCGTTGTTGAACGGGGGCTTTCCCACAACACGGTTGTGAGCTATGA
ACGGGATTTGAACAGCTACGCCGCCTATTTAGAGGAGCAGGAGCAGCTGAGCTCTTTTGACCAGGTGACAAGGCTGCACA
TCATCCAGTTTTTGAAGCATTTAAAAGACGCCGGAAAATCCGGAAAGACGGTCGCGAGGCATCTCGCTTCCATCCGCAGC
TTTCACCAGTTTCTGCTGAGGGAAAAAGTGACGGCCCAGGACCCGTCCGTCCATATTGAATCGCAAAAAACGGAACGGAC
CCTTCCGAAGGTGCTGTCATTACAGGAAGTCGAAACGCTTTTGGATACGCCGAAGCTGACGGGGCCGTTCGGCTACCGCG
ATAAAGCAATGCTGGAGTTATTGTATGCGACAGGAATCCGCGTCAGCGAGATGATCGCATTAAAGCTGTCCGATGTCCAT
TTATCGATGGGCTTTATCCGCTGCTTCGGGAAAGGAAGAAAGGAGCGGATCGTTCCGCTCGGCGAAGCGGCGTCACATGC
GGTCGGCGAATATCTGTCAAAAGCGAGGGGCAAGCTTTTGAAAAAAAATACCGAAGACGCCCTGTTTCTGAATCACCACG
GCAGACAAATGAGCCGCCAGGGGTTTTGGAAAAATTTAAAGAAAATCGCTTTGGAAGCGGGAATTAATAAAGAGCTGACG
CCGCACACGCTGAGGCACTCATTCGCCACACACTTGCTCGAAAACGGAGCCGATCTCCGGGCCGTTCAGGAAATGCTCGG
ACACGCCGACATTTCGACGACGCAAATTTATACGCACGTGACGAAAACAAGGCTGAAAGATGTGTATAGGCAATACCATC
CCCGTGCATAG

Upstream 100 bases:

>100_bases
TGAAGGAGCAGCCCTCAAGGTCGCCTCGATGGAAGAGGACGAGCAGGGCAGCTGGTTTAACCGGTTAATCTTTTTTTATT
TGAACGGGGAGTAGGATAGC

Downstream 100 bases:

>100_bases
CCTGAAAGGACAGGCGGTAGCACGGTTTTTCATGTTGAGGGAGTAGCAAATTGCGGGAAGTTTCTCACTATTTCCGTTCG
TATTGTCAACTGTTGTGTAA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKVHIKDFIHYAVVERGLSHNTVVSYERDLNSYAAYLEEQEQLSSFDQVTRLHIIQFLKHLKDAGKSGKTVARHLASIRS
FHQFLLREKVTAQDPSVHIESQKTERTLPKVLSLQEVETLLDTPKLTGPFGYRDKAMLELLYATGIRVSEMIALKLSDVH
LSMGFIRCFGKGRKERIVPLGEAASHAVGEYLSKARGKLLKKNTEDALFLNHHGRQMSRQGFWKNLKKIALEAGINKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYRQYHPRA

Sequences:

>Translated_296_residues
MKVHIKDFIHYAVVERGLSHNTVVSYERDLNSYAAYLEEQEQLSSFDQVTRLHIIQFLKHLKDAGKSGKTVARHLASIRS
FHQFLLREKVTAQDPSVHIESQKTERTLPKVLSLQEVETLLDTPKLTGPFGYRDKAMLELLYATGIRVSEMIALKLSDVH
LSMGFIRCFGKGRKERIVPLGEAASHAVGEYLSKARGKLLKKNTEDALFLNHHGRQMSRQGFWKNLKKIALEAGINKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYRQYHPRA
>Mature_296_residues
MKVHIKDFIHYAVVERGLSHNTVVSYERDLNSYAAYLEEQEQLSSFDQVTRLHIIQFLKHLKDAGKSGKTVARHLASIRS
FHQFLLREKVTAQDPSVHIESQKTERTLPKVLSLQEVETLLDTPKLTGPFGYRDKAMLELLYATGIRVSEMIALKLSDVH
LSMGFIRCFGKGRKERIVPLGEAASHAVGEYLSKARGKLLKKNTEDALFLNHHGRQMSRQGFWKNLKKIALEAGINKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYRQYHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=45.7337883959044, Blast_Score=253, Evalue=8e-69,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=35.6164383561644, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1790768, Length=182, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790767, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33786; Mature: 33786

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVHIKDFIHYAVVERGLSHNTVVSYERDLNSYAAYLEEQEQLSSFDQVTRLHIIQFLKH
CEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDAGKSGKTVARHLASIRSFHQFLLREKVTAQDPSVHIESQKTERTLPKVLSLQEVETL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LDTPKLTGPFGYRDKAMLELLYATGIRVSEMIALKLSDVHLSMGFIRCFGKGRKERIVPL
HCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEAASHAVGEYLSKARGKLLKKNTEDALFLNHHGRQMSRQGFWKNLKKIALEAGINKELT
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYRQYHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVHIKDFIHYAVVERGLSHNTVVSYERDLNSYAAYLEEQEQLSSFDQVTRLHIIQFLKH
CEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDAGKSGKTVARHLASIRSFHQFLLREKVTAQDPSVHIESQKTERTLPKVLSLQEVETL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LDTPKLTGPFGYRDKAMLELLYATGIRVSEMIALKLSDVHLSMGFIRCFGKGRKERIVPL
HCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEAASHAVGEYLSKARGKLLKKNTEDALFLNHHGRQMSRQGFWKNLKKIALEAGINKELT
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYRQYHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]