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The map label for this gene is resA

Identifier: 52786200

GI number: 52786200

Start: 2398257

End: 2398790

Strand: Reverse

Name: resA

Synonym: BLi02461

Alternate gene names: 52786200

Gene position: 2398790-2398257 (Counterclockwise)

Preceding gene: 52786201

Following gene: 52786199

Centisome position: 56.81

GC content: 47.57

Gene sequence:

>534_bases
ATGAAAAAAAAGCGTTTTTACATTCGGACAGGCATCCTCCTTGTGCTGCTTGCAGCGCTTGGCTACACGCTGTACAGCGC
CGTGTTTCAAAACACGGAGAGTGTGGCGGTGGGGGAAAAAGCTCCCATTTTTTCGCTGGAGGATGTTGACGGCAACCGTC
TCAAACTGGACGAACTAAAAGGCAAAGGGGTATTTTTAAACTTTTGGGGAACATGGTGCGAACCATGCAAAAGAGAATTT
CCTTATATGGCGAATCAATACAAGGTGTTTAAGGATAAAGGGGTGGAAATCGTCGCCGTCAATGTCGGCGAATCGAACCT
CGCCGTCAGAAACTTTATGAAAGACCACGGCGTCAATTTTCCGGTTGTGCTTGATAAAGACAGGCAGGTCCTTAACGCAT
ATGATGTCACACCGCTGCCGACCACGTTTTTGATCAACCCTGACGGAGAGATTGTCAAGGTCGTGACGGGCGAGATGACA
GAACGGATGATCCACGATTATATGAATATGATCAAACCAGAGGGATCGTCATGA

Upstream 100 bases:

>100_bases
AGCGGCTTTCTAAATTTTCACACAACCTTCAAAAAAGGCAAATGGCAGTCAGTCTTGAGATGATATAATGATACTGAATG
TCTACATGAGGGGGCGGATT

Downstream 100 bases:

>100_bases
TGAAAGAAATCAAATGCGAATGCGGCCATGTGAATCCGGCGGGTACCGTTTTGTGTGAATCGTGCGGAAAGCCGCTGGTC
AAACAGGATGCCAAACTCCT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKKKRFYIRTGILLVLLAALGYTLYSAVFQNTESVAVGEKAPIFSLEDVDGNRLKLDELKGKGVFLNFWGTWCEPCKREF
PYMANQYKVFKDKGVEIVAVNVGESNLAVRNFMKDHGVNFPVVLDKDRQVLNAYDVTPLPTTFLINPDGEIVKVVTGEMT
ERMIHDYMNMIKPEGSS

Sequences:

>Translated_177_residues
MKKKRFYIRTGILLVLLAALGYTLYSAVFQNTESVAVGEKAPIFSLEDVDGNRLKLDELKGKGVFLNFWGTWCEPCKREF
PYMANQYKVFKDKGVEIVAVNVGESNLAVRNFMKDHGVNFPVVLDKDRQVLNAYDVTPLPTTFLINPDGEIVKVVTGEMT
ERMIHDYMNMIKPEGSS
>Mature_177_residues
MKKKRFYIRTGILLVLLAALGYTLYSAVFQNTESVAVGEKAPIFSLEDVDGNRLKLDELKGKGVFLNFWGTWCEPCKREF
PYMANQYKVFKDKGVEIVAVNVGESNLAVRNFMKDHGVNFPVVLDKDRQVLNAYDVTPLPTTFLINPDGEIVKVVTGEMT
ERMIHDYMNMIKPEGSS

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788523, Length=181, Percent_Identity=31.4917127071823, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESA_BACLD (Q65HX8)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079620.1
- RefSeq:   YP_092029.1
- HSSP:   P35160
- ProteinModelPortal:   Q65HX8
- SMR:   Q65HX8
- STRING:   Q65HX8
- EnsemblBacteria:   EBBACT00000054621
- EnsemblBacteria:   EBBACT00000062537
- GeneID:   3029180
- GeneID:   3101231
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02461
- KEGG:   bli:BL00661
- NMPDR:   fig|279010.5.peg.307
- eggNOG:   COG0526
- GeneTree:   EBGT00050000000761
- HOGENOM:   HBG493509
- OMA:   FFATNCK
- ProtClustDB:   PRK03147
- BioCyc:   BLIC279010-1:BLI02461-MONOMER
- BioCyc:   BLIC279010:BL00661-MONOMER
- HAMAP:   MF_01319
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 20049; Mature: 20049

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10bf4c50)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRFYIRTGILLVLLAALGYTLYSAVFQNTESVAVGEKAPIFSLEDVDGNRLKLDELK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCEEEEEECC
GKGVFLNFWGTWCEPCKREFPYMANQYKVFKDKGVEIVAVNVGESNLAVRNFMKDHGVNF
CCEEEEEECCCHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCC
PVVLDKDRQVLNAYDVTPLPTTFLINPDGEIVKVVTGEMTERMIHDYMNMIKPEGSS
CEEECCCCCEEHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MKKKRFYIRTGILLVLLAALGYTLYSAVFQNTESVAVGEKAPIFSLEDVDGNRLKLDELK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCEEEEEECC
GKGVFLNFWGTWCEPCKREFPYMANQYKVFKDKGVEIVAVNVGESNLAVRNFMKDHGVNF
CCEEEEEECCCHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCC
PVVLDKDRQVLNAYDVTPLPTTFLINPDGEIVKVVTGEMTERMIHDYMNMIKPEGSS
CEEECCCCCEEHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA