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The map label for this gene is engA [H]

Identifier: 52786163

GI number: 52786163

Start: 2360901

End: 2362211

Strand: Reverse

Name: engA [H]

Synonym: BLi02421

Alternate gene names: 52786163

Gene position: 2362211-2360901 (Counterclockwise)

Preceding gene: 52786164

Following gene: 52786162

Centisome position: 55.94

GC content: 48.21

Gene sequence:

>1311_bases
ATGGGAAAACCTGTCGTAGCCATAGTTGGAAGACCCAATGTGGGGAAGTCCACGATCTTTAACAGGATCGCGGGCGAAAG
AATTTCGATTGTGGAAGATACACCTGGCGTGACGCGGGATCGGATATACAGCTCTGCCGAGTGGCTGAATCACGACTTCA
ACCTGATTGATACAGGCGGAATCGAAGTCGGCGATGAGCCGTTTTTGGCGCAGATTCGCCATCAGGCCGAGATCGCCATG
GAAGAAGCAGATGTGATTATTTTCATGACGAACGGCCGCGAAGGCGTCACAGCCGCTGATGAAGAAGTGGCAAAAATTTT
ATACCGTACAAAAAAACCCGTCGTTCTGGCGGTTAATAAAGTGGATAATCCTGAAATGAGAGCAAACATTTACGATTTTT
ATGCCCTCGGCTTTGGCGAGCCGTTCCCGATTTCAGGGACGCATGGCCTTGGTCTCGGCGATCTGCTTGACGCGGTCAGC
GAACATTTTAAAAACATACCCGAGACGAAGTATGAGGATGAAGTCGTTCAATTTTGCCTCATCGGCCGGCCGAACGTCGG
AAAATCCTCCCTTGTAAACGCCATGATTGGAGAAGAGCGCGTTATCGTCAGCAATATTGCGGGAACGACGCGCGACGCCA
TTGACACGAGGTTTACATACAATCAAAGAGACTTTGTCATCGTGGATACAGCCGGGATGAGAAAAAAGGGGAAAGTGTAT
GAGGCAACTGAAAAATACAGCGTCCTCCGAGCTTTAAAGGCGATCGACCGTTCAGAAGTCGTCTGCGTCGTCTTGGACGG
CGAAGAAGGCATTATTGAGCAGGACAAGCGGATTGCCGGCTATGCGCATGAAGCAGGAAAAGCTGTTGTCATCGTCGTAA
ACAAATGGGATGCAGTCGAAAAAGACGAGCGGACGATGAAAGAATTTGAAGAAAAGGTTAGAGACCACTTTCAATTTTTG
GACTACGCGCCTGTTTTGTTTATGTCCGCTTTGACTAAAAAGCGCATCCATACGCTGATGCCTGCGGTCATGACGGCGAG
CGAAAACCATTCGATGAGGGTGCAGACCAATATTCTTAATGATATCATTATGGATGCGGTGGCTATGAACCCGACGCCGA
CGCATAATGGAAACCGGTTAAAAATTTATTATGCGACACAAGTGGCTGTGAAGCCGCCGACATTTGTCGTATTTGTCAAT
GACCCTGAGCTGATGCATTTTTCTTACGAACGCTTTTTGGAAAACCGGATACGCGACGCCTTCGGATTTGAAGGAACACC
AATCAGGATTTTCGCAAGAGCAAGAAAATAA

Upstream 100 bases:

>100_bases
AAGAAGGGTTTCTTTCTTCAAACTGATTTTTTGAAAAGAGAAACAAATGATCATTCATTTAAAGATGGAAAAGCTTTACT
GAATTGAAAGGAAGGGTACT

Downstream 100 bases:

>100_bases
AGAGGTGTAGTAAAAATGACAAAAGTATCGATTTTGGGAGCCGGAAGCTGGGGAACAGCCTTGGCGCTCGTTTTGGCGGA
CAACCAGTACGATGTGTGCA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNHDFNLIDTGGIEVGDEPFLAQIRHQAEIAM
EEADVIIFMTNGREGVTAADEEVAKILYRTKKPVVLAVNKVDNPEMRANIYDFYALGFGEPFPISGTHGLGLGDLLDAVS
EHFKNIPETKYEDEVVQFCLIGRPNVGKSSLVNAMIGEERVIVSNIAGTTRDAIDTRFTYNQRDFVIVDTAGMRKKGKVY
EATEKYSVLRALKAIDRSEVVCVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVEKDERTMKEFEEKVRDHFQFL
DYAPVLFMSALTKKRIHTLMPAVMTASENHSMRVQTNILNDIIMDAVAMNPTPTHNGNRLKIYYATQVAVKPPTFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIRIFARARK

Sequences:

>Translated_436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNHDFNLIDTGGIEVGDEPFLAQIRHQAEIAM
EEADVIIFMTNGREGVTAADEEVAKILYRTKKPVVLAVNKVDNPEMRANIYDFYALGFGEPFPISGTHGLGLGDLLDAVS
EHFKNIPETKYEDEVVQFCLIGRPNVGKSSLVNAMIGEERVIVSNIAGTTRDAIDTRFTYNQRDFVIVDTAGMRKKGKVY
EATEKYSVLRALKAIDRSEVVCVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVEKDERTMKEFEEKVRDHFQFL
DYAPVLFMSALTKKRIHTLMPAVMTASENHSMRVQTNILNDIIMDAVAMNPTPTHNGNRLKIYYATQVAVKPPTFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIRIFARARK
>Mature_435_residues
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNHDFNLIDTGGIEVGDEPFLAQIRHQAEIAME
EADVIIFMTNGREGVTAADEEVAKILYRTKKPVVLAVNKVDNPEMRANIYDFYALGFGEPFPISGTHGLGLGDLLDAVSE
HFKNIPETKYEDEVVQFCLIGRPNVGKSSLVNAMIGEERVIVSNIAGTTRDAIDTRFTYNQRDFVIVDTAGMRKKGKVYE
ATEKYSVLRALKAIDRSEVVCVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVEKDERTMKEFEEKVRDHFQFLD
YAPVLFMSALTKKRIHTLMPAVMTASENHSMRVQTNILNDIIMDAVAMNPTPTHNGNRLKIYYATQVAVKPPTFVVFVND
PELMHFSYERFLENRIRDAFGFEGTPIRIFARARK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=38.2417582417582, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1788919, Length=172, Percent_Identity=33.1395348837209, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=38.2978723404255, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=87, Percent_Identity=41.3793103448276, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=206, Percent_Identity=30.0970873786408, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550813, Length=183, Percent_Identity=28.9617486338798, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48981; Mature: 48849

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNHDFNLIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCC
IEVGDEPFLAQIRHQAEIAMEEADVIIFMTNGREGVTAADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
VDNPEMRANIYDFYALGFGEPFPISGTHGLGLGDLLDAVSEHFKNIPETKYEDEVVQFCL
CCCCHHHCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
IGRPNVGKSSLVNAMIGEERVIVSNIAGTTRDAIDTRFTYNQRDFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHCCEEEECCCCEEEEECCCCCCCCCEE
EATEKYSVLRALKAIDRSEVVCVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVE
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDERTMKEFEEKVRDHFQFLDYAPVLFMSALTKKRIHTLMPAVMTASENHSMRVQTNILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
DIIMDAVAMNPTPTHNGNRLKIYYATQVAVKPPTFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIRIFARARK
HCCCCCCEEEEEECCC
>Mature Secondary Structure 
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNHDFNLIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCC
IEVGDEPFLAQIRHQAEIAMEEADVIIFMTNGREGVTAADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
VDNPEMRANIYDFYALGFGEPFPISGTHGLGLGDLLDAVSEHFKNIPETKYEDEVVQFCL
CCCCHHHCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
IGRPNVGKSSLVNAMIGEERVIVSNIAGTTRDAIDTRFTYNQRDFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHCCEEEECCCCEEEEECCCCCCCCCEE
EATEKYSVLRALKAIDRSEVVCVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVE
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDERTMKEFEEKVRDHFQFLDYAPVLFMSALTKKRIHTLMPAVMTASENHSMRVQTNILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
DIIMDAVAMNPTPTHNGNRLKIYYATQVAVKPPTFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIRIFARARK
HCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA