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The map label for this gene is aroB

Identifier: 52786149

GI number: 52786149

Start: 2348743

End: 2349831

Strand: Reverse

Name: aroB

Synonym: BLi02405

Alternate gene names: 52786149

Gene position: 2349831-2348743 (Counterclockwise)

Preceding gene: 52786150

Following gene: 52786148

Centisome position: 55.65

GC content: 48.76

Gene sequence:

>1089_bases
ATGAAATCACTTCAAATCGAAACCGCTTCTTTGTCCTACCCGGTATTCATCGGGGGAGGCATTAGAAAAAACGCGGCAGA
GCTTTTGTCATCCTTGAACCTTCCGATGACGAAACTGCTTTTGATCACCGACGAAGAAGTTGATAAACGCTATGGAGAAG
AGCTGTTCAGTCTTCTCCGCAGCAAATGGCCCGTCAAAAAGGTTGCGGTGCCAAGCGGCGAGCAGGCCAAATCCATCGAT
ATGTTTATGAAGCTCCAGACGGAAGCCATTCAATTTCACCTTGACCGCTCGTCATGCATTGTGGCGCTGGGCGGCGGTGT
TGTCGGCGATCTTGCAGGATTCGTCGCTTCAACTTTTATGAGGGGCATCGATTATGTGCAATTCCCAACGACTCTGCTGT
CTCATGACAGCGCAGTCGGAGGGAAAGTGGCCATTAATCACCCGCTCGGAAAAAACTTAATCGGCGCTTTTCATCAGCCG
AAGGCGGTGGTATATGACACCGAATGCCTGAGCACGCTTCCGGAAAAAGAAATGCGTTCAGGTCTTGCGGAAGTCATTAA
GCACGCATTTATCCGTGATGAATCTTTCTTGAACGAATTGCTTAAACTTGATTCAATAGAAGCGATTACGACCGGCCAGC
TCAGTGAAATGGTTTACAAAGGCATTTCGATTAAAGCGGAAGTTGTCTCACAAGACGAACGCGAACAGGGAATCAGGGCC
TATTTGAACTTCGGGCATACGCTTGGCCACGCCGTTGAAGCCGAATACGGCTACGGAGAGATCACCCATGGCGATGCCGT
CGCTTTAGGCATGCAATTTGCTTTGTTTGTCAGCGAGAAGGTGCTGAATTGTCCTGTTGACCGTACGAAAATCGCCGCCT
GGCTGAAAAATCTCGGCTATCCGGAAAGCGTGAAACGCGAAGTTTCAACAGAAGCCCTTATCTATCGAATGATGAACGAT
AAAAAAACACGCGGAGGCATCATTCAGTTTGTCCTTCTGGATAAGATCGGCAGTGTGCGGCTGCACTCCTTTAAAGCCGA
AGAAATCGAACGATGGCTGAATATGTGGAGATTGGAGGGAGACAAATGA

Upstream 100 bases:

>100_bases
GGGAAATCGCAAATGCGATCGTCGAGCAGTTTGGCGTTGACCAAATGGACCGGATCGCTGAAAATGTTGAGAAAATGAGA
AAGCTTGCGAGGGAGTTTTA

Downstream 100 bases:

>100_bases
TGATGCGCGGTATTCGGGGAGCGACGACCATTGACCGGGATACAGAAAAAGACATTACGGAGCGGACGAAGCAGCTGATC
GGAAAAATGATCGATGAAAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKSLQIETASLSYPVFIGGGIRKNAAELLSSLNLPMTKLLLITDEEVDKRYGEELFSLLRSKWPVKKVAVPSGEQAKSID
MFMKLQTEAIQFHLDRSSCIVALGGGVVGDLAGFVASTFMRGIDYVQFPTTLLSHDSAVGGKVAINHPLGKNLIGAFHQP
KAVVYDTECLSTLPEKEMRSGLAEVIKHAFIRDESFLNELLKLDSIEAITTGQLSEMVYKGISIKAEVVSQDEREQGIRA
YLNFGHTLGHAVEAEYGYGEITHGDAVALGMQFALFVSEKVLNCPVDRTKIAAWLKNLGYPESVKREVSTEALIYRMMND
KKTRGGIIQFVLLDKIGSVRLHSFKAEEIERWLNMWRLEGDK

Sequences:

>Translated_362_residues
MKSLQIETASLSYPVFIGGGIRKNAAELLSSLNLPMTKLLLITDEEVDKRYGEELFSLLRSKWPVKKVAVPSGEQAKSID
MFMKLQTEAIQFHLDRSSCIVALGGGVVGDLAGFVASTFMRGIDYVQFPTTLLSHDSAVGGKVAINHPLGKNLIGAFHQP
KAVVYDTECLSTLPEKEMRSGLAEVIKHAFIRDESFLNELLKLDSIEAITTGQLSEMVYKGISIKAEVVSQDEREQGIRA
YLNFGHTLGHAVEAEYGYGEITHGDAVALGMQFALFVSEKVLNCPVDRTKIAAWLKNLGYPESVKREVSTEALIYRMMND
KKTRGGIIQFVLLDKIGSVRLHSFKAEEIERWLNMWRLEGDK
>Mature_362_residues
MKSLQIETASLSYPVFIGGGIRKNAAELLSSLNLPMTKLLLITDEEVDKRYGEELFSLLRSKWPVKKVAVPSGEQAKSID
MFMKLQTEAIQFHLDRSSCIVALGGGVVGDLAGFVASTFMRGIDYVQFPTTLLSHDSAVGGKVAINHPLGKNLIGAFHQP
KAVVYDTECLSTLPEKEMRSGLAEVIKHAFIRDESFLNELLKLDSIEAITTGQLSEMVYKGISIKAEVVSQDEREQGIRA
YLNFGHTLGHAVEAEYGYGEITHGDAVALGMQFALFVSEKVLNCPVDRTKIAAWLKNLGYPESVKREVSTEALIYRMMND
KKTRGGIIQFVLLDKIGSVRLHSFKAEEIERWLNMWRLEGDK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=356, Percent_Identity=41.5730337078652, Blast_Score=246, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320332, Length=355, Percent_Identity=35.4929577464789, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BACLD (Q65I29)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079569.2
- RefSeq:   YP_091978.1
- ProteinModelPortal:   Q65I29
- SMR:   Q65I29
- STRING:   Q65I29
- EnsemblBacteria:   EBBACT00000056520
- EnsemblBacteria:   EBBACT00000061235
- GeneID:   3029357
- GeneID:   3097453
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02405
- KEGG:   bli:BL02777
- NMPDR:   fig|279010.5.peg.256
- eggNOG:   COG0337
- GeneTree:   EBGT00050000002325
- HOGENOM:   HBG632303
- OMA:   YINEFAL
- ProtClustDB:   PRK00002
- BioCyc:   BLIC279010-1:BLI02405-MONOMER
- BioCyc:   BLIC279010:BL02777-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40202; Mature: 40202

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLQIETASLSYPVFIGGGIRKNAAELLSSLNLPMTKLLLITDEEVDKRYGEELFSLLR
CCCCEEEECCCCCCEEECCCCCHHHHHHHHHCCCCHHEEEEEECHHHHHHHHHHHHHHHH
SKWPVKKVAVPSGEQAKSIDMFMKLQTEAIQFHLDRSSCIVALGGGVVGDLAGFVASTFM
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHH
RGIDYVQFPTTLLSHDSAVGGKVAINHPLGKNLIGAFHQPKAVVYDTECLSTLPEKEMRS
HHCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCCCEEEEEHHHHHHCCHHHHHH
GLAEVIKHAFIRDESFLNELLKLDSIEAITTGQLSEMVYKGISIKAEVVSQDEREQGIRA
HHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHH
YLNFGHTLGHAVEAEYGYGEITHGDAVALGMQFALFVSEKVLNCPVDRTKIAAWLKNLGY
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
PESVKREVSTEALIYRMMNDKKTRGGIIQFVLLDKIGSVRLHSFKAEEIERWLNMWRLEG
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCEEECCCHHHHHHHHHHHHCCC
DK
CC
>Mature Secondary Structure
MKSLQIETASLSYPVFIGGGIRKNAAELLSSLNLPMTKLLLITDEEVDKRYGEELFSLLR
CCCCEEEECCCCCCEEECCCCCHHHHHHHHHCCCCHHEEEEEECHHHHHHHHHHHHHHHH
SKWPVKKVAVPSGEQAKSIDMFMKLQTEAIQFHLDRSSCIVALGGGVVGDLAGFVASTFM
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHH
RGIDYVQFPTTLLSHDSAVGGKVAINHPLGKNLIGAFHQPKAVVYDTECLSTLPEKEMRS
HHCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCCCEEEEEHHHHHHCCHHHHHH
GLAEVIKHAFIRDESFLNELLKLDSIEAITTGQLSEMVYKGISIKAEVVSQDEREQGIRA
HHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHH
YLNFGHTLGHAVEAEYGYGEITHGDAVALGMQFALFVSEKVLNCPVDRTKIAAWLKNLGY
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
PESVKREVSTEALIYRMMNDKKTRGGIIQFVLLDKIGSVRLHSFKAEEIERWLNMWRLEG
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCEEECCCHHHHHHHHHHHHCCC
DK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA