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The map label for this gene is trpD

Identifier: 52786146

GI number: 52786146

Start: 2345582

End: 2346598

Strand: Reverse

Name: trpD

Synonym: BLi02402

Alternate gene names: 52786146

Gene position: 2346598-2345582 (Counterclockwise)

Preceding gene: 52786147

Following gene: 52786145

Centisome position: 55.57

GC content: 52.8

Gene sequence:

>1017_bases
ATGAACGAACTGCTGAAATCATGCGTTAACGGACGGACACTGAATGAAATCGAGGCACACAGCATCATGCGCGACATGAT
GACCGGCTCGCTGAGCGCTGCGGAAATCGGAGGCCTCCTGTCCGTTCTCGCCTACAGGGGAGAAACGGCTGAAGAGATTA
CGGGATTTGTCAGAGCCATGCGGGAGCAGGCGCATACAATAGACGGACCGGAACATGTTGTTGATACGTGCGGAACCGGA
GGAGACGGAAGCTCCACCTTCAACATTTCCACAGCGGCTGCGATCATCGCTTCATCAGCCGGGGCAAAAATCGCAAAACA
CGGTAATCGATCCGTTTCTTCAAAAAGCGGGAGCGCTGACGTTCTCGAATATCTCGGCGTTTCTATTCAGACGTCGCCTG
AAGAAACGATTAAGAGCATTGAACGCCGAAATATGGGATTCCTGTATGCGCCAAGCTATCACTCTTCCATGAAGCACGTG
GCAGGCGCGAGGAAGGATCTGGCTTTTAGAACCGTATTCAATCTGCTCGGCCCGCTCAGCAACCCGATGAAGGCCAAACG
CCAGGTGATCGGCGTCTACTCGATCGAAAAAGCAAAGCTTATGGCCCGCGCTCTTGAAGCGTTTGAACCGGAGCACGTAT
TGTTTGTTTCGAGCCGGGACGGTCTTGATGAACTGTCGATCACATCGCCGACAGATGTAATTGAACTGAAAGGCGGCAAA
ACATACGAATACACCGTCGAGCCGGGCGATGTTGGACTGCCTCTCGGAAGGCTGAGAGACATTCAGGTGGCGACGCCTGA
AGAAAGCGGCCGTCTGATCGTCGATATTTTGAAAAACCGCGGTCCGGACTCGGCTGTTCATATCGCAGCGTTTAATGCCG
GAGCCGCTTTATACGTCGCAGAACAGGCAGCGGATTTAAAAGAGGGCGTTGCGCTCGCTTTAGAAGCTGTTGCTGGCGGT
GAAGCGCTCAATCAGCTGGAGCGATTAAAACAGAAAGAGGAAGAGTTGTATGCTTAA

Upstream 100 bases:

>100_bases
CCTGAAAAAGAATGGGAAGAGACCTGCAATAAAGCAGGGGCTCTGTTAAAAACGATTCAAATCGCAGAAGAAACGTTTCT
CGAAAAGGGGGAGGACGGCA

Downstream 100 bases:

>100_bases
TCAAATTATTGATAGAAAACGAGAAGACATCCTAAAGATCAAGCTGTCGGAAGATTTAAAACTGCCAAAGCGGTCATTTA
AAAAAGCGCTCCTTTCTCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAMREQAHTIDGPEHVVDTCGTG
GDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSADVLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHV
AGARKDLAFRTVFNLLGPLSNPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGK
TYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVAEQAADLKEGVALALEAVAGG
EALNQLERLKQKEEELYA

Sequences:

>Translated_338_residues
MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAMREQAHTIDGPEHVVDTCGTG
GDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSADVLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHV
AGARKDLAFRTVFNLLGPLSNPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGK
TYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVAEQAADLKEGVALALEAVAGG
EALNQLERLKQKEEELYA
>Mature_338_residues
MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAMREQAHTIDGPEHVVDTCGTG
GDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSADVLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHV
AGARKDLAFRTVFNLLGPLSNPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGK
TYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVAEQAADLKEGVALALEAVAGG
EALNQLERLKQKEEELYA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=33.9339339339339, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320561, Length=282, Percent_Identity=34.3971631205674, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACLD (Q65I32)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079566.1
- RefSeq:   YP_091975.1
- ProteinModelPortal:   Q65I32
- STRING:   Q65I32
- EnsemblBacteria:   EBBACT00000057670
- EnsemblBacteria:   EBBACT00000058978
- GeneID:   3028190
- GeneID:   3100737
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02402
- KEGG:   bli:BL02774
- NMPDR:   fig|279010.5.peg.252
- eggNOG:   COG0547
- GeneTree:   EBGT00050000002544
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   BLIC279010-1:BLI02402-MONOMER
- BioCyc:   BLIC279010:BL02774-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAM
CHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
REQAHTIDGPEHVVDTCGTGGDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSAD
HHHHHCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHH
VLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHVAGARKDLAFRTVFNLLGPLS
HHHHHCCCEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCC
TYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVA
EEEEEECCCCCCCCHHHCCEEEEECCCCCCCEEEEHHHCCCCCCEEEEEEECCCEEEEEH
EQAADLKEGVALALEAVAGGEALNQLERLKQKEEELYA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAM
CHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
REQAHTIDGPEHVVDTCGTGGDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSAD
HHHHHCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHH
VLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHVAGARKDLAFRTVFNLLGPLS
HHHHHCCCEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCC
TYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVA
EEEEEECCCCCCCCHHHCCEEEEECCCCCCCEEEEHHHCCCCCCEEEEEEECCCEEEEEH
EQAADLKEGVALALEAVAGGEALNQLERLKQKEEELYA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA